Primary study of expression of TROP-2 in human pulmonary adenocarcinoma and cell lines

Chinese Journal of Cancer Prevention and Treatment

Volumn 20, Issue 5, 2013, Pages 342-346

  Gu, Yu Ping ^a   Zhao, Yun Gen ^b   Zhu, Yi Bei ^a   Zhang, Guang Bo ^a   Huang, Jian An ^a  

^a THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b the Second People s Hospital of Changshu   (China)

Author keywords

Flow cytometry; Immunohistochemistry; Pulmonary adenocarcinoma; RT PCR; TROP 2

Indexed keywords

MESSENGER RNA;

ARTICLE; CANCER CELL CULTURE; CANCER PATIENT; CANCER TISSUE; CLINICAL FEATURE; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA;

EID: 84886929700     PISSN: 16735269     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Trerotola M, Cantanelli P, Guerra E, et al. Upregulation of Trop-2 quantitatively stimulates human cancer growth[J]. Oncogene, 2012, 36: 1-12.
2. Wang J, Day R, Dong Y, et al. Identification of TROP-2 as an oncogene and an attractive therapeutic target in colon cancers[J]. Mol Cancer Ther, 2008, 7(2): 280-285.
3. Mühlmann G, Spizzo G, Gostner J, et al. TROP2 expression as prognostic marker for gastric carcinoma[J]. J Clin Pathol, 2009, 62(2): 152-158.
4. Neagu M, Constantin C, Tanase C, et al. Patented biomarker panels in early detection of cancer[J]. Recent Patents on Biomarkers, 2011, 1(1): 10-24.
5. Kobayashi H, Minami Y, Anami Y, et al. Expression of the GA733 gene family and its relationship to prognosis in pulmonary adenocarcinoma[J]. Virchows Arch, 2010, 457(1): 69-76.
6. Fang YJ, Lu ZH, Wang GQ, et al. Elevated expressions of MMP7, TROP2, and surviving are associated with survival, disease recurrence, and liver metastasis of colon cance[J]. Int J Colorectal Dis, 2009, 24(8): 875-884.
7. Fong D, Spizzo G, Gostner JM, et al. TROP2: a novel prognostic marker in squamous cell carcinoma of the oral cavity[J]. Mod Pathol, 2008, 21(2): 186-191.
8. Fong D, Moser P, Krammel C, et al. High expression of TROP2 correlates with poor prognosis in pancreatic cancer[J]. Br J Cancer, 2008, 99(8): 1290-1295.
9. Bignotti E, Todeschini P, Calza S, et al. Trop-2 overexpression as an independent marker for poor overall survival in ovarian carcinoma patients[J]. Eur J Cancer, 2010, 46(5): 944-953.
10. 2010, 27(9): 1272-1274.
11. Pak MG, Shin DH, Lee CH, et al. Significance of EpCAM and TROP2 expression in non-small cell lung cancer[J]. World J Surg Oncol, 2012, 10(1): 53-60.
12. 2008, 15(14): 289-292.
13. 2011, 18(4): 306-308.
14. Frederick BA, Helfrich BA, Coldren CD, et al. Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma[J]. Mol Cancer Ther, 2007, 6(6): 1683-1691.