Blood neutrophil-to-lymphocyte ratio predicts survival in patients with unresectable hepatocellular carcinoma undergoing transarterial chemoembolization

Chinese Journal of Cancer Prevention and Treatment

Volumn 20, Issue 7, 2013, Pages 522-525

  Li, Jin Peng ^a,b   Hu, Shan Liang ^a,b   Chen, Hua ^a,b   Bu, Wen Zhe ^a,b   Song, Jin Long ^a  

^a SHANDONG CANCER HOSPITAL AND INSTITUTE   (China)

^b UNIVERSITY OF JINAN   (China)

Author keywords

Carcinoma, hepatocellular; Liver neoplasms; Neutrophil to lymphocyte ratio; Prognosis; Transarterial chemoembolization

Indexed keywords

ANTINEOPLASTIC AGENT;

AGE; ARTICLE; CANCER SURVIVAL; CHEMOEMBOLIZATION; CLINICAL FEATURE; CONTROLLED STUDY; HUMAN; LIVER CELL CARCINOMA; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; NEUTROPHIL; NEUTROPHIL COUNT; OVERALL SURVIVAL; PREDICTIVE VALUE; RETROSPECTIVE STUDY; TREATMENT OUTCOME;

EID: 84886925862     PISSN: 16735269     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Llovet JM, Burroughs A, Bruix J. Hepatocellular carcinoma[J]. Lancet, 2003, 362(9399): 1907-1917.
2. Rougier P, Mitry E, Barbare JC, et al. Hepatocellular carcinoma (HCC): an update[J]. Semin Oncol, 2007, 34(2): 12-20.
3. Gomez D, Farid S, Malik HZ, et al. Preoperative neutrophil-to-lympho-cyte ratio as a prognostic predictor after curative resection for hepatocellular carcinoma[J]. World J Surg, 2008, 32(8): 1757-1762.
4. Cook EJ, Walsh SR, et al. Post-operative neutrophil-lymphocyte ratio predicts complications following colorectal surgery[J]. Int J Surg, 2007, 5(1): 27-30.
5. Guo ZX, Wei W, Zhong C, et al. Correlation of preoperative neutrophil-to-lymphocyte ratio to prognosis of young patients with hepatocellular carcinoma[J]. Chin J Cancer, 2009, 28(11): 1203-1208.
6. Kishi Y, Kopetz S, Chun YS, et al. Blood neutrophil-to-lymphocyte ratio predicts survival in patients with colorectal liver metastases treated with systemic chemotherapy[J]. Ann Surg Oncol, 2009, 16(16): 614-622.
7. Kusumanto YH, Dam WA, Hospers GA, et al. Platelets and granulocytes, in particular the neutrophils, form important compartments for circulating vascular endothelial growth factor[J]. Angiogenesis, 2008, 6(4): 283-287.
8. Gong Y, Koh DR. Neutrophils promote inflammatory angiogenesis via release of preformed VEGF in an in vivo corneal model[J]. Cell Tissue Res, 2010, 339(2): 437-448.
9. Ray-Coquard I, Cropet C, Van Glabbeke M, et al. Lymphopenia as a prognostic factor for overall survival in advanced carcinomas, sarcomas, and lymphomas[J]. Cancer Res, 2009, 69(3): 5383-5391.
10. Zerbini A, Pilli M, Laccabue D, et al. Radiofrequency thermal ablation for hepatocellular carcinoma stimulates autologous NK-cell response[J]. Gastroenterology, 2010, 138(5): 1931-1942.
11. Neagoe PE, Brkovic A, Hajjar F, et al. Expression and release of angiopoietin-1 from human neutrophils: intracellular mechanisms[J]. Growth Factors, 2009, 27(6): 335-344.
12. Rashid F, Waraich N, Bhatti I, et al. A pre-operative elevated neutrophil: lymphocyte ratio does not predict survival from oesophageal cancer resection[J]. World J Surg Oncol, 2010, 8: 1.