Bayesian hierarchical modeling of patient subpopulations: Efficient designs of Phase II oncology clinical trials

Clinical Trials

Volumn 10, Issue 5, 2013, Pages 720-734

  Berry, Scott M ^a   Broglio, Kristine R ^a   Groshen, Susan ^b   Berry, Donald A ^a,c  

^a LLC   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTICAL ERROR; BAYES THEOREM; CONFERENCE PAPER; HUMAN; HYPOTHESIS; MATHEMATICAL MODEL; NEOPLASM; PHASE 2 CLINICAL TRIAL (TOPIC); POPULATION; PRIORITY JOURNAL; SAMPLE SIZE; SIMULATION; STUDY DESIGN;

BAYES THEOREM; CLINICAL TRIALS, PHASE II AS TOPIC; COMPUTER SIMULATION; DATA INTERPRETATION, STATISTICAL; HUMANS; MEDICAL ONCOLOGY; ROC CURVE; SAMPLE SIZE;

EID: 84886896973     PISSN: 17407745     EISSN: 17407753     Source Type: Journal    
DOI: 10.1177/1740774513497539     Document Type: Conference Paper

References (25)

1. Hamburg MA, Collins FS. The path to personalized medicine. N Engl J Med. 2010 ; 363 (4). 301-04
2. Simon R. Clinical trials for predictive medicine: New challenges and paradigms. Clin Trials. 2010 ; 7 (5). 516-24
3. Berry SM, Carlin BP, Lee JJ, Muller P Bayesian Adaptive Methods for Clinical Trials. Boca Raton, FL: CRC Press ; 2011:
4. Berry DA. Bayesian clinical trials. Nat Rev Drug Discov. 2006 ; 5 (1). 27-36
5. Stein C. Inadmissibility of the usual estimator for the mean of a multivariate normal distribution. Proc Third Berkeley Symp Math Stat Probab. 1956 ; 1: 197-206
6. James W, Stein C. Estimation with quadratic loss. Proc Fourth Berkeley Symp Math Stat Probab. 1961 ; 1: 361-79
7. Bernardo JM, Smith AFM Bayesian Theory. New York: Wiley, Chichester ; 1994:
8. Berry DA. Bayesian approaches for comparative effectiveness research. Clin Trials. 2012 ; 9 (1). 37-47
9. Berry SM, Berry DA. Accounting for multiplicities in assessing drug safety: A three-level hierarchical mixture model. Biometrics. 2004 ; 60 (2). 418-26
10. Berry SM, Berry DA, Natarajan K, et al. Bayesian survival analysis with nonproportional hazards: Metanalysis of combination pravastatin-aspirin. J Am Stat Assoc. 2004 ; 99 (465). 36-44
11. Berry SM, Ishak KJ, Luce BR, Berry DA. Bayesian meta-analysis for comparative effectiveness and informing coverage decisions. Med Care. 2010 ; 48 (6). S137-44
12. Berry DA, Stangl D Bayesian Biostatistics. New York: Marcel Dekker ; 1996:
13. Brown ER, Ibrahim JG. A Bayesian semiparametric joint hierarchical model for longitudinal and survival data. Biometrics. 2003 ; 59 (2). 221-28
14. Carlin BP, Louis TA Bayes and Empirical Bayes Methods for Data Analysis. Boca Raton, FL: Chapman & Hall/CRC ; 2000:
15. Davis C, Leffingwell D. Empirical Bayes estimates of subgroup effects in clinical trials. Control Clin Trials. 1990 ; 11: 37-42
16. Dixon DO, Simon R. Bayesian subset analysis. Biometrics. 1991 ; 47: 871-81
17. Jones H, Ohlssen D, Neuenschwander B, Racine A, Branson M. Bayesian models for subgroup analysis in clinical trials. Clin Trials. 2011 ; 8 (2). 129-43
18. Louis TA. Estimating a population of parameter values using Bayes and empirical Bayes methods. J Am Stat Assoc. 1984 ; 79 (386). 393-98
19. Simon R. Bayesian subset analysis: Application to studying treatment-by-gender interactions. Stat Med. 2002 ; 21: 2909-16
20. Skene AM, Wakefield JC. Hierarchical models for multicentre binary response studies. Stat Med. 1990 ; 9 (8). 919-29
21. Stangl DK. Prediction and decision making using Bayesian hierarchical models. Stat Med. 1995 ; 14 (20). 2173-90
22. Thall PF, Wathen JK, Bekele BN, et al. Hierarchical Bayesian approaches to phase II trials in diseases with multiple subtypes. Stat Med. 2003 ; 22 (5). 763-80
23. Chugh R, Wathen JK, Maki RG, et al. Phase II multicenter trial of imatinib in 10 histologic subtypes of sarcoma using a Bayesian hierarchical statistical model. J Clin Oncol. 2009 ; 27 (19). 3148-53
24. Simon R. Optimal two-stage designs for phase II clinical trials. Control Clin Trials. 1989 ; 10 (1). 1-10
25. Gelman A. Prior distributions for variance parameters in hierarchical models. Bayesian Anal. 2006 ; 1 (3). 515-34