Arginine residues on the opposite side of the active site stimulate the catalysis of ribosome depurination by ricin A chain by interacting with the P-protein stalk

Journal of Biological Chemistry

Volumn 288, Issue 42, 2013, Pages 30270-30284

  Li, Xiao Ping ^a   Kahn, Peter C ^b   Kahn, Jennifer Nielsen ^a   Grela, Przemyslaw ^a   Tumer, Nilgun E ^a  

^a The State University of New Jersey   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ARGININE RESIDUE; DEPURINATION; P-PROTEIN; RICIN A CHAINS;

CHAINS;

ARGININE;

ALPHA SARCIN; ARGININE; GLYCINE DEHYDROGENASE (DECARBOXYLATING); RICIN; RICIN A; RICIN B; RNA; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CELL METABOLISM; CELL SURFACE; CONTROLLED STUDY; DEPURINATION; ENZYME ACTIVE SITE; GENE ACTIVITY; GENE INTERACTION; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; RESIDUE ANALYSIS; RIBOSOME; STRUCTURAL HOMOLOGY; WILD TYPE;

PROTEIN SYNTHESIS; RIBOSOMAL RNA (RRNA); RIBOSOME-INACTIVATING PROTEIN; RIBOSOMES; RICIN; RIP; TOXINS;

ADENINE; ARGININE; CATALYSIS; CATALYTIC DOMAIN; PROTEIN BINDING; RIBOSOMES; RICIN; SACCHAROMYCES CEREVISIAE;

EID: 84886884229     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.510966     Document Type: Article

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