Silver dressings improve diabetic wound healing without reducing bioburden

Wounds

Volumn 25, Issue 10, 2013, Pages 293-301

  Finley, Phillip J ^a   Huckfeldt, Roger E ^a   Walker, Kara D ^b   Shornick, Laurie P ^c  

^a Mercy Hospital   (United States)

^b MISSOURI STATE UNIVERSITY   (United States)

^c SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

bacteria; biofilm; biology of wound healing; diabetes; silver dressings

Indexed keywords

EID: 84886881668     PISSN: 10447946     EISSN: 19432704     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Centers for Disease Control and Prevention. 2011 National Diabetes Fact Sheet. http://www.cdc.gov/diabetes/pubs/pdf/ndfs-2011.pdf. Published 2011. Accessed September 16, 2013.
2. Brem H, Tomic-Canic M. Cellular and molecular basis of wound healing in diabetes. J Clin Invest. 2007;117(5):1219-1222. (Pubitemid 46718408)
3. Lansdown AB. Silver. I: Its antibacterial properties and mechanism of action. J Wound Care. 2002;11(4):125-130.
4. Dowsett C. The use of silver-based dressings in wound care. Nurs Stand. 2004;19(7):56-60.
5. Lansdown AB. Silver in health care: antimicrobial effects and safety in use. Curr Probl Dermatol. 2006;33:17-34. (Pubitemid 44670142)
6. Lansdown AB. Silver. 2: Toxicity in mammals and how its products aid wound repair. J Wound Care. 2002;11(5):173-177.
7. Feng QL, Wu J, Chen GQ, Cui FZ, Kim TN, Kim JO. A mechanistic study of the antibacterial effect of silver ions on Escherichia coli and Staphylococcus aureus. J Biomed Mater Res. 2000;52(4):662-668.
8. Nwomeh BC, Yager DR, Cohen IK. Physiology of the chronic wound. Clin Plast Surg. 1998;25(3):341-356. (Pubitemid 28343176)
9. Armstrong DG, Jude EB. The role of matrix metalloproteinases in wound healing. J Am Podiatr Med Assoc. 2002;92(1):12-18. (Pubitemid 44383824)
10. Nadworny PL, Wang J, Tredget EE, Burrell RE. Anti-inflammatory activity of nanocrystalline silver in a porcine contact dermatitis model. Nanomedicine. 2008;4(3):241-251.
11. Warriner R, Burrell R. Infection and the chronic wound: a focus on silver. Adv Skin Wound Care. 2005;18(suppl 1):2-12.
12. Wright JB, Lam K, Buret AG, Olson ME, Burrell RE. Early healing events in a porcine model of contaminated wounds: effects of nanocrystalline silver on matrix metalloproteinases, cell apoptosis, and healing. Wound Repair Regen. 2002;10(3):141-151. (Pubitemid 34760892)
13. Bhol KC, Alroy J, Schechter PJ. Anti-inflammatory effect of topical nanocrystalline silver cream on allergic contact dermatitis in a guinea pig model. Clin Exp Dermatol. 2004;29(3):282-287. (Pubitemid 38658472)
14. Bhol KC, Schechter PJ. Topical nanocrystalline silver cream suppresses inflammatory cytokines and induces apoptosis of inflammatory cells in a murine model of allergic contact dermatitis. Br J Dermatol. 2005;152(6):1235-1242. (Pubitemid 40933423)
15. Galiano RD, Michaels J 5th, Dobryansky M, Levine JP, Gurtner GC. Quantitative and reproducible murine model of excisional wound healing. Wound Repair Regen. 2004;12(4):485-492. (Pubitemid 39007049)
16. Buchanan K, Heimbach DM, Minshew BH, Coyle MB. Comparison of quantitative and semiquantitative culture techniques for burn biopsy. J Clin Microbiol. 1986;23(2):258-261. (Pubitemid 16155284)
17. Robson MC. Wound infection. A failure of wound healing caused by an imbalance of bacteria. Surg Clin North Am. 1997;77(3):637-650. (Pubitemid 27256038)
18. Heggers JP. Assessing and controlling wound infection. Clin Plast Surg. 2003;30(1):25-35. (Pubitemid 36288298)
19. Gozalo AS, Hoffmann VJ, Brinster LR, Elkins WR, Ding L, Holland SM. Spontaneous Staphylococcus xylosus infection in mice deficient in NADPH oxidase and comparison with other laboratory mouse strains. J Am Assoc Lab Anim Sci. 2010;49(4):480-486.
20. Bradfield JF, Wagner JE, Boivin GP, Steffen EK, Russell RJ. Epizootic fatal dermatitis in athymic nude mice due to Staphylococcus xylosus. Lab Anim Sci. 1993;43(1):111-113. (Pubitemid 23075453)
21. Gjødsbøl K, Christensen JJ, Karlsmark T, Jørgensen B, Klein BM, Krogfelt KA. Multiple bacterial species reside in chronic wounds: a longitudinal study. Int Wound J. 2006;3(3):225-231.
22. Kirketerp-Møller K, Jensen PØ, Fazli M, et al. Distribution, organization, and ecology of bacteria in chronic wounds. J Clin Microbiol. 2008;46(8):2717-2722.
23. James GA, Swogger E, Wolcott R, et al. Biofilms in chronic wounds. Wound Repair Regen. 2008;16(1):37-44.
24. Wolcott RD, Rhoads DD. A study of biofilm-based wound management in subjects with critical limb ischaemia. J Wound Care. 2008;17(4):145-148, 150-152, 154-155.
25. Davis SC, Ricotti C, Cazzaniga A, Welsh E, Eaglstein WH, Mertz PM. Microscopic and physiologic evidence for biofilm-associated wound colonization in vivo. Wound Repair Regen. 2008;16(1):23-29.
26. Zhao G, Hochwalt PC, Usui ML, et al. Delayed wound healing in diabetic (db/db) mice with Pseudomonas aeruginosa biofilm challenge: a model for the study of chronic wounds. Wound Repair Regen. 2010;18(5):467-477.
27. Zhao G, Usui ML, Underwood RA, et al. Time course study of delayed wound healing in a biofilm-challenged diabetic mouse model. Wound Repair Regen. 2012;20(3):342-352.
28. Velander P, Theopold C, Hirsch T, et al. Impaired wound healing in an acute diabetic pig model and the effects of local hyperglycemia. Wound Repair Regen. 2008;16(2):288-293. (Pubitemid 351342136)
29. Pan Y, Breidt F Jr, Gorski L. Synergistic effects of sodium chloride, glucose, and temperature on biofilm formation by Listeria monocytogenes serotype 1/2a and 4b strains. Appl Environ Microbiol. 2010;76(5):1433-1441.
30. Jefferson KK. What drives bacteria to produce a biofilm? FEMS Microbiol Lett. 2004;236(2):163-173. (Pubitemid 38900921)
31. Lim Y, Jana M, Luong TT, Lee CY. Control of glucose-and NaCl-induced biofilm formation by rbf in Staphylococcus aureus. J Bacteriol. 2004;186(3):722-729. (Pubitemid 38129650)
32. Bjarnsholt T, Kirketerp-Møller K, Kristiansen S, et al. Silver against Pseudomonas aeruginosa biofilms. APMIS. 2007;115(8):921-928. (Pubitemid 47256284)