Dorsomedial hypothalamic lesions block syrian hamster testicular regression in short day lengths without diminishing increased testosterone negative-feedback sensitivity

Biology of Reproduction

Volumn 89, Issue 2, 2013, Pages

  Jarjisian, Stephan G ^a   Piekarski, David J ^a   Place, Ned J ^b   Driscoll, Joseph R ^a   Paxton, Eve G ^a   Kriegsfeld, Lance J ^a   Zucker, Irving ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Department of Obstetrics Gynecology   (United States)

Author keywords

FSH; Hypothalamus; Prolactin; Seasonal reproduction; Testosterone

Indexed keywords

FOLLITROPIN; MELATONIN; PROLACTIN; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DAY LENGTH; DORSOMEDIAL HYPOTHALAMIC NUCLEUS; GONAD FUNCTION; HISTOPATHOLOGY; HORMONE INHIBITION; HORMONE RELEASE; HORMONE SENSITIVITY; MALE; NEGATIVE FEEDBACK; NERVE CELL NETWORK; NONHUMAN; PINEAL BODY; PRIORITY JOURNAL; SEASONAL VARIATION; SYRIAN HAMSTER; TARGET ORGAN; TESTICULAR REGRESSION; TESTIS DISEASE; ANIMAL; BLOOD; FEEDBACK SYSTEM; HAMSTER; HYPOTHALAMUS; METABOLISM; PHOTOPERIODICITY; PHYSIOLOGY; SEASON; SEASONAL REPRODUCTION; SECRETION (PROCESS); TESTIS;

FSH; HYPOTHALAMUS; PROLACTIN; SEASONAL REPRODUCTION; TESTOSTERONE;

ANIMALS; CRICETINAE; DORSOMEDIAL HYPOTHALAMIC NUCLEUS; FEEDBACK, PHYSIOLOGICAL; FOLLICLE STIMULATING HORMONE; MALE; MELATONIN; MESOCRICETUS; PHOTOPERIOD; PINEAL GLAND; PROLACTIN; SEASONS; TESTIS; TESTOSTERONE;

EID: 84886880205     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.113.109587     Document Type: Article

References (39)

1. Goldman BD. Mammalian photoperiodic system: formal properties and neuroendocrine mechanisms of photoperiodic time measurement. J Biol Rhythms 2001; 16:283-301.
2. Paul MJ, Zucker I, Schwartz WJ. Tracking the seasons: the internal calendars of vertebrates. Philos Trans R Soc Lond B Biol Sci 2008; 363: 341-361.
3. Prendergast BJ, Nelson RJ, Zucker I. Mammalian seasonal rhythms: Behavior and neuroendocrine substrates In: Pfaff D, Arnold A, Etgen A, Fahrbach S, Moss R, Rubin R (eds.), Hormones, Brain, and Behavior, vol. 2. San Diego: Elsevier Science Press; 2002:93-156.
4. Beery AK, Trumbull JJ, Tsao JM, Costantini RM, Zucker I. Sex differences in the onset of seasonal reproductive quiescence in hamsters. Proc Biol Sci 2007; 274:281-286.
5. Butler MP, Turner KW, Park JH, Schoomer EE, Zucker I, Gorman MR. Seasonal regulation of reproduction: altered role of melatonin under naturalistic conditions in hamsters. Proc Biol Sci 2010; 277:2867-2874.
6. Reiter RJ. Th e pineal and its hormones in the control of reproduction in mammals. Endocr Rev 1980; 1:109-131.
7. Seegal RF, Goldman BD. Effects of photoperiod on cyclicity and serum gonadotropins in the Syrian hamster. Biol Reprod 1975; 12:223-231.
8. Bartness TJ , Powers JB, Hastings MH, Bittman EL, Goldman BD. The timed infusion paradigm for melatonin delivery: what has it taught us about the melatonin signal, its reception, and the photoperiodic control of seasonal responses? J Pineal Res 1993; 15:161-190.
9. Bittman EL, Dempsey RJ, Karsch FJ. Pineal melatonin secretion drives the reproductive response to daylength in the ewe. Endocrinology 1983; 113: 2276-2283.
10. Carter DS, Goldman BD. Antigonadal effects of timed melatonin infusion in pinealectomized male Djungarian hamsters (Phodopus sungorus sungorus): duration is the critical parameter. Endocrinology 1983; 113: 1261-267.
11. Darrow JM, G oldman BD. Circadian regulation of pineal melatonin and reproduction in the Djungarian hamster. J Biol Rhythms 1986; 1:39-54.
12. Kriegsfeld LJ, Bittman EL. Photoperiodism and reproduction in mammals In: Nelson RJ, Denlinger DL (eds.), Photoperiodism: the Biological Calendar. NY: Oxford University Press; 2010;503-542.
13. Prendergast BJ. MT1 melatonin receptors mediate somatic, behavioral, and reproductive neuroendocrine responses to photoperiod and melatonin in Siberian hamsters (Phodopus sungorus). Endocrinology 2010; 151: 714-721.
14. Freeman DA, Zucker I. Refractoriness to melatonin occurs independently at multiple brain sites in Siberian hamsters. Proc Natl Acad Sci U S A 2001; 98:6447-6452.
15. Badura LL, Goldman BD. Central sites mediating reproductive responses to melatonin in juvenile male Siberian hamsters. Brain Res 1992; 598: 98-106.
16. Maywood ES , Hastings MH. Lesions of the iodomelatonin-binding sites of the mediobasal hypothalamus spare the lactotropic, but block the gonadotropic response of male Syrian hamsters to short photoperiod and to melatonin. Endocrinology 1995; 136:144-153.
17. Maywood ES , Bittman EL, Hastings MH. Lesions of the melatonin- and androgen-responsive tissue of the dorsomedial nucleus of the hypothalamus block the gonadal response of male Syrian hamsters to programmed infusions of melatonin. Biol Reprod 1996; 54:470-477.
18. Raitiere M N, Garyfallou VT, Urbanski HF. Lesions in the anterior bed nucleus of the stria terminalis in Syrian hamsters block short-photoperiodinduced testicular regression. Biol Reprod 1997; 57:796-806.
19. Bittman EL , Crandell RG, Lehman MN. Influences of the paraventricular and suprachiasmatic nuclei and olfactory bulbs on melatonin responses in the golden hamster. Biol Reprod 1989; 40:118-126.
20. Bittman EL , Goldman BD, Zucker I. Testicular responses to melatonin are altered by lesions of the suprachiasmatic nuclei in golden hamsters Biol Reprod 1979; 21:647-656.
21. Leitner C, Bartness TJ. An intact dorsomedial hypothalamic nucleus, but not the subzona incerta or reuniens nucleus, is necessary for short-day melatonin signal-induced responses in Siberian hamsters. Neuroendocrinology 2011; 93:29-39.
22. Bae HH, Mangels RA, Cho BS, Dark J, Yellon SM, Zucker I. Ventromedial hypothalamic mediation of photoperiodic gonadal responses in male Syrian hamsters. J Biol Rhythms 1999; 14:391-401.
23. Lewis D, Freeman DA, Dark J, Wynne-Edwards KE, Zucker I. Photoperiodic control of oestrous cycles in Syrian hamsters: mediation by the mediobasal hypothalamus. J Neuroendocrinol 2002; 14:294-299.
24. Ellis GB, Turek FW. Time course of the photoperiod-induced change in sensitivity of the hypothalamic-pituitary axis to testosterone feedback in castrated male hamsters. Endocrinology 1979; 104:625-630.
25. Arteaga-Si lva M, Márquez-Villanueva Y, Martínez-García R, Hernández-González M, Bonilla-Jaime H, Retana-Márquez S. Effects of hormonal replacement with androgens and estrogens on male sexual behavior and plasma levels of these steroids in gonadectomized golden hamsters (Mesocricetus auratus). Physiol Behav 2005; 85:571-580.
26. Campbell C S, Finkelstein JS, Turek FW. The interaction of photoperiod and testosterone on the development of copulatory behavior in castrated male hamsters. Physiol Behav 1978; 21:409-415.
27. Park JH, Spencer EM, Place NJ, Jordan CL, Zucker I. Seasonal control of penile development of Siberian hamsters (Phodopus sungorus) by daylength and testicular hormones. Reproduction 2003; 125:397-407.
28. Mason AO, Duffy S, Zhao S, Ubuka T, Bentley GE, Tsutsui K, Silver R, Kriegsfeld LJ. Photoperiod and reproductive condition are associated with changes in RFamide-related peptide (RFRP) expression in Syrian hamsters (Mesocricetus auratus). J Biol Rhythms 2010; 25:176-185.
29. Ancel C, Bentsen AH, Sébert ME, Tena-Sempere M, Mikkelsen JD, Simonneaux V. Stimulatory effect of RFRP-3 on the gonadotrophic axis in the male Syrian hamster: the exception proves the rule. Endocrinology 2012; 153:1352-1363.
30. Watson-Whitmyre M, Stetson MH. A mathematical method for estimating paired testes weight from in situ testicular measurements in three species of hamster. Anat Rec 1985; 213:473-476.
31. Bast JD, Greenwald GS. Serum profiles of follicle-stimulating hormone, luteinizing hormone and prolactin during the estrous cycle of the hamster. Endocrinology 1974; 94:1295-1299.
32. Soares MJ, Colosi P, Talamantes F. Development of a homologous radioimmunoassay for secreted hamster prolactin. Proc Soc Exp Biol Med 1983; 172:379-381.
33. Leitner C, Bartness TJ. Distributed forebrain sites mediate melatonininduced short-day responses in Siberian hamsters. Endocrinology 2010; 151:3133-3140.
34. Hileman SM, McManus CJ, Goodman RL, Jansen HT. Neurons of the lateral preoptic area/rostral anterior hypothalamic area are required for photoperiodic inhibition of estrous cyclicity in sheep. Biol Reprod 2011; 85:1057-1065.
35. Bi S, Kim YJ , Zheng F. Dorsomedial hypothalamic NPY and energy balance control. Neuropeptides 2012; 46:309-314.
36. Woller MJ, Campbell GT, Blake CA. Neuropeptide Y and luteinizing hormone releasing hormone synergize to stimulate the development of cellular follicle-stimulating hormone in the hamster adenohypophysis. J Neuroendocrinol 1995; 7:733-736.
37. Revel FG, Saboureau M, Pévet P, Simonneaux V, Mikkelsen JD. RFamide-related peptide gene is a melatonin-driven photoperiodic gene. Endocrinology 2008; 149:902-912.
38. Tsutsui K, Ubuka T, Bentley GE, Kriegsfeld LJ. Gonadotropin-inhibitory hormone (GnIH): discovery, progress and prospect. Gen Comp Endocrinol 2012; 177:305-314.
39. Kriegsfeld LJ, Mei DF, Bentley GE, Ubuka T, Mason AO, Inoue K, Ukena K, Tsutsui K, Silver R. Identification and characterization of a gonadotropin-inhibitory system in the brains of mammals. Proc Natl Acad Sci U S A 2006; 103:2410-2415.