메뉴 건너뛰기




Volumn 405, Issue 12, 2013, Pages 4077-4088

Metabolism of levamisole and kinetics of levamisole and aminorex in urine by means of LC-QTOF-HRMS and LC-QqQ-MS

Author keywords

Aminorex; LC MS; LC QTOF HRMS; Levamisole; Metabolism

Indexed keywords

BIOMOLECULES; CALIBRATION; ISOMERS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; ORGANIC POLYMERS; SULFUR COMPOUNDS;

EID: 84886867131     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-013-6829-x     Document Type: Article
Times cited : (39)

References (30)
  • 2
    • 80052317838 scopus 로고    scopus 로고
    • Analysis of illicit cocaine and heroin samples seized in Luxembourg from 2005-2010
    • Schneider S, Meys F (2011) Analysis of illicit cocaine and heroin samples seized in Luxembourg from 2005-2010. Forensic Sci Int 212:242-246
    • (2011) Forensic Sci Int , vol.212 , pp. 242-246
    • Schneider, S.1    Meys, F.2
  • 3
    • 84859124867 scopus 로고    scopus 로고
    • Levamisole in cocaine: Unexpected news from an old acquaintance
    • Larocque A, Hoffman RS (2012) Levamisole in cocaine: unexpected news from an old acquaintance. Clin Toxicol (Phila) 50:231-241
    • (2012) Clin Toxicol (Phila) , vol.50 , pp. 231-241
    • Larocque, A.1    Hoffman, R.S.2
  • 5
    • 61949464329 scopus 로고    scopus 로고
    • Aminorex and rexamino as metabolites of levamisole in the horse
    • Ho EN, Leung DK, Leung GN et al (2009) Aminorex and rexamino as metabolites of levamisole in the horse. Anal Chim Acta 638:58-68
    • (2009) Anal Chim Acta , vol.638 , pp. 58-68
    • Ho, E.N.1    Leung, D.K.2    Leung, G.N.3
  • 7
    • 60849110287 scopus 로고    scopus 로고
    • Agranulocytosis after consumption of cocaine adulterated with levamisole
    • Zhu NY, Legatt DF, Turner AR (2009) Agranulocytosis after consumption of cocaine adulterated with levamisole. Ann Intern Med 150:287-289
    • (2009) Ann Intern Med , vol.150 , pp. 287-289
    • Zhu, N.Y.1    Legatt, D.F.2    Turner, A.R.3
  • 8
    • 84862104673 scopus 로고    scopus 로고
    • Immune-mediated agranulocytosis caused by the cocaine adulterant levamisole: A case for reactive metabolite(s) involvement
    • Wolford A, McDonald TS, Eng H et al (2012) Immune-mediated agranulocytosis caused by the cocaine adulterant levamisole: a case for reactive metabolite(s) involvement. Drug Metab Dispos 40:1067-1075
    • (2012) Drug Metab Dispos , vol.40 , pp. 1067-1075
    • Wolford, A.1    McDonald, T.S.2    Eng, H.3
  • 9
    • 84856387601 scopus 로고    scopus 로고
    • Agranulocytosis and other consequences due to use of illicit cocaine contaminated with levamisole
    • Buchanan JA, Lavonas EJ (2012) Agranulocytosis and other consequences due to use of illicit cocaine contaminated with levamisole. Curr Opin Hematol 19:27-31
    • (2012) Curr Opin Hematol , vol.19 , pp. 27-31
    • Buchanan, J.A.1    Lavonas, E.J.2
  • 10
    • 78449287586 scopus 로고    scopus 로고
    • Cocaine-related retiform purpura: Evidence to incriminate the adulterant, levamisole
    • Walsh NM, Green PJ, Burlingame RW, Pasternak S, Hanly JG (2010) Cocaine-related retiform purpura: evidence to incriminate the adulterant, levamisole. J Cutan Pathol 37:1212-1219
    • (2010) J Cutan Pathol , vol.37 , pp. 1212-1219
    • Walsh, N.M.1    Green, P.J.2    Burlingame, R.W.3    Pasternak, S.4    Hanly, J.G.5
  • 12
    • 84862104673 scopus 로고    scopus 로고
    • Immune-mediated agranulocytosis caused by the cocaine adulterant levamisole: A case for reactive metabolite(s) involvement
    • Wolford A, McDonald TS, Eng H et al (2012) Immune-mediated agranulocytosis caused by the cocaine adulterant levamisole: a case for reactive metabolite(s) involvement. Drug Metab Dispos 40:1067-1075
    • (2012) Drug Metab Dispos , vol.40 , pp. 1067-1075
    • Wolford, A.1    McDonald, T.S.2    Eng, H.3
  • 14
    • 61949464329 scopus 로고    scopus 로고
    • Aminorex and rexamino as metabolites of levamisole in the horse
    • Ho EN, Leung DK, Leung GN et al (2009) Aminorex and rexamino as metabolites of levamisole in the horse. Anal Chim Acta 638:58-68
    • (2009) Anal Chim Acta , vol.638 , pp. 58-68
    • Ho, E.N.1    Leung, D.K.2    Leung, G.N.3
  • 15
    • 79954589307 scopus 로고    scopus 로고
    • Detection of levamisole exposure in cocaine users by liquid chromatographytandem mass spectrometry
    • Lynch KL, Dominy SS, Graf J, Kral AH (2011) Detection of levamisole exposure in cocaine users by liquid chromatographytandem mass spectrometry. J Anal Toxicol 35:176-178
    • (2011) J Anal Toxicol , vol.35 , pp. 176-178
    • Lynch, K.L.1    Dominy, S.S.2    Graf, J.3    Kral, A.H.4
  • 17
    • 61949464329 scopus 로고    scopus 로고
    • Aminorex and rexamino as metabolites of levamisole in the horse
    • Ho EN, Leung DK, Leung GN et al (2009) Aminorex and rexamino as metabolites of levamisole in the horse. Anal Chim Acta 638:58-68
    • (2009) Anal Chim Acta , vol.638 , pp. 58-68
    • Ho, E.N.1    Leung, D.K.2    Leung, G.N.3
  • 18
    • 82855181645 scopus 로고    scopus 로고
    • Determination of levamisole in urine by gas chromatography-mass spectrometry
    • Trehy ML, Brown DJ, Woodruff JT et al (2011) Determination of levamisole in urine by gas chromatography-mass spectrometry. J Anal Toxicol 35:545-550
    • (2011) J Anal Toxicol , vol.35 , pp. 545-550
    • Trehy, M.L.1    Brown, D.J.2    Woodruff, J.T.3
  • 19
    • 0019726264 scopus 로고
    • Determination of levamisole in plasma and animal tissues by gas chromatography with thermionic specific detection
    • Woestenborghs R, Michielsen L, Heykants J (1981) Determination of levamisole in plasma and animal tissues by gas chromatography with thermionic specific detection. J Chromatogr 224:25-32
    • (1981) J Chromatogr , vol.224 , pp. 25-32
    • Woestenborghs, R.1    Michielsen, L.2    Heykants, J.3
  • 20
    • 0022620425 scopus 로고
    • Novel assay and pharmacokinetics of levamisole and p-hydroxylevamisole in human plasma and urine
    • Kouassi E, Caille G, Lery L, Lariviere L, Vezina M (1986) Novel assay and pharmacokinetics of levamisole and p-hydroxylevamisole in human plasma and urine. Biopharm Drug Dispos 7:71-89
    • (1986) Biopharm Drug Dispos , vol.7 , pp. 71-89
    • Kouassi, E.1    Caille, G.2    Lery, L.3    Lariviere, L.4    Vezina, M.5
  • 21
    • 84892985151 scopus 로고    scopus 로고
    • Bioanalytical methods for quantitation of levamisole, a widespread cocaine adulterant
    • Shea JL (2012) Bioanalytical methods for quantitation of levamisole, a widespread cocaine adulterant. Clin Chem Lab Med 1-8
    • (2012) Clin Chem Lab Med , pp. 1-8
    • Shea, J.L.1
  • 22
    • 61949464329 scopus 로고    scopus 로고
    • Aminorex and rexamino as metabolites of levamisole in the horse
    • Ho EN, Leung DK, Leung GN et al (2009) Aminorex and rexamino as metabolites of levamisole in the horse. Anal Chim Acta 638:58-68
    • (2009) Anal Chim Acta , vol.638 , pp. 58-68
    • Ho, E.N.1    Leung, D.K.2    Leung, G.N.3
  • 24
    • 79954441243 scopus 로고    scopus 로고
    • Development and practical application of a library of CID accurate mass spectra of more than 2,500 toxic compounds for systematic toxicological analysis by LC-QTOF-MS with data-dependent acquisition
    • Broecker S, Herre S, Wust B, Zweigenbaum J, Pragst F (2011) Development and practical application of a library of CID accurate mass spectra of more than 2,500 toxic compounds for systematic toxicological analysis by LC-QTOF-MS with data-dependent acquisition. Anal Bioanal Chem 400:101-117
    • (2011) Anal Bioanal Chem , vol.400 , pp. 101-117
    • Broecker, S.1    Herre, S.2    Wust, B.3    Zweigenbaum, J.4    Pragst, F.5
  • 25
    • 84860241800 scopus 로고    scopus 로고
    • Detection of metabolites in the general unknown screening of hair by LC-QTOF-MS
    • Broecker S, Koch M, Pragst F (2011) Detection of metabolites in the general unknown screening of hair by LC-QTOF-MS. Ann Tox Anal 23:S1-S12
    • (2011) Ann Tox Anal , vol.23
    • Broecker, S.1    Koch, M.2    Pragst, F.3
  • 27
    • 0032011562 scopus 로고    scopus 로고
    • Matrix effect in quantitative LC/MS/MS analyses of biological fluids: A method for determination of finasteride in human plasma at picogram per milliliter concentrations
    • Matuszewski BK, Constanzer ML, Chavez-Eng CM (1998) Matrix effect in quantitative LC/MS/MS analyses of biological fluids: A method for determination of finasteride in human plasma at picogram per milliliter concentrations. Anal Chem 70:882-889
    • (1998) Anal Chem , vol.70 , pp. 882-889
    • Matuszewski, B.K.1    Constanzer, M.L.2    Chavez-Eng, C.M.3
  • 29
    • 79954589307 scopus 로고    scopus 로고
    • Detection of levamisole exposure in cocaine users by liquid chromatographytandem mass spectrometry
    • Lynch KL, Dominy SS, Graf J, Kral AH (2011) Detection of levamisole exposure in cocaine users by liquid chromatographytandem mass spectrometry. J Anal Toxicol 35:176-178
    • (2011) J Anal Toxicol , vol.35 , pp. 176-178
    • Lynch, K.L.1    Dominy, S.S.2    Graf, J.3    Kral, A.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.