Early fetal gender determination using real-time PCR analysis of cell-free fetal DNA during 6th-10th weeks of gestation

Acta Medica Iranica

Volumn 51, Issue 4, 2013, Pages 209-214

  Khorram Khorshid, Hamid Reza ^a   Zargari, Maryam ^b,c   Sadeghi, Mohammad Reza ^c   Edallatkhah, Haleh ^c   Shahhosseiny, Mohammad Hassan ^d   Kamali, Koorosh ^c  

^a UNIVERSITY OF SOCIAL WELFARE AND REHABILITATION SCIENCES   (Iran)

^b ISLAMIC AZAD UNIVERSITY   (Iran)

^c AVICENNA RESEARCH INSTITUTE   (Iran)

^d ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Cell free fetal DNA; Fetal sex determination; Human Y chromosome; Prenatal diagnosis

Indexed keywords

CELL FREE FETAL DNA; DNA; UNCLASSIFIED DRUG; DAZ1 PROTEIN, HUMAN; RNA BINDING PROTEIN;

ADULT; ARTICLE; CELL FREE SYSTEM; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DNA EXTRACTION; FEMALE; FETUS; FIRST TRIMESTER PREGNANCY; GENE SEQUENCE; GENETIC DISORDER; GESTATIONAL AGE; HUMAN; MALE; MIDDLE AGED; PREDICTIVE VALUE; PREGNANCY; PRENATAL DIAGNOSIS; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SEX DETERMINATION; SRY GENE; Y CHROMOSOME; ADOLESCENT; BLOOD; GENETICS;

ADOLESCENT; ADULT; CHROMOSOMES, HUMAN, Y; DNA; FEMALE; FETUS; GENES, SRY; GESTATIONAL AGE; HUMANS; MALE; MIDDLE AGED; PREGNANCY; PRENATAL DIAGNOSIS; REAL-TIME POLYMERASE CHAIN REACTION; RNA-BINDING PROTEINS; SENSITIVITY AND SPECIFICITY; SEX DETERMINATION ANALYSIS; YOUNG ADULT;

EID: 84886857468     PISSN: 00446025     EISSN: 17359694     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Bischoff FZ, Lewis DE, Simpson JL. Cell-free fetal DNA in maternal blood: kinetics, source and structure. Human reproduction update 2005;11(1):59-67.
2. Shulman LP, Elias S. Amniocentesis and chorionic villus sampling. The Western Journal of Medicine 1993;159(3):260-8.
3. Lo YM, Corbetta N, Chamberlain PF, Rai V, Sargent IL, Redman CW, Wainscoat JS. Presence of fetal DNA in maternal plasma and serum. Lancet 1997;350(9076):485-7.
4. Alberry M, Maddocks D, Jones M, Abdel Hadi M, Abdel-Fattah S, Avent N, Soothill PW. Free fetal DNA in maternal plasma in anembryonic pregnancies: confirmation that the origin is the trophoblast. Prenatal Diagnosis 2007;27(5):415-8.
5. Lo YM, Tein MS, Lau TK, Haines CJ, Leung TN, Poon PM, Wainscoat JS, Johnson PJ, Chang AM, Hjelm NM. Quantitative analysis of fetal DNA in maternal plasma and serum: implications for non invasive prenatal diagnosis. American Journal of Human Genetics 1998;62(4):768-75.
6. Angert RM, LeShane ES, Lo YM, Chan LY, Delli-Bovi LC and Bianchi DW. Fetal cell-free plasma DNA concentrations in maternal blood are stable 24 hours after collection: analysis of first-and third trimester samples. Clin Chem 2003;49(1):195-8.
7. Lo YM, Zhang J, Leung TN, Lau TK, Chang AM, Hjelm NM. Rapid clearance of fetal DNA from maternal plasma. American Journal of Human Genetics 1999;64(1):218-24.
8. Wright CF, Burton H. The use of cell-free fetal nucleic acids in maternal blood for non-invasive prenatal diagnosis. Human reproduction update 2009;15(1):139-51.
9. Lo YM, Corbetta N, Chamberlain PF, Rai V, Sargent IL, Redman CW, Wainscoat JS. Presence of fetal DNA in maternal plasma and serum. Lancet 1997;350(9076):485-7.
10. Picchiassi E, Coata G, Fanetti A, Centra M, Pennacchi L, Di Renzo GC. The best approach for early prediction of fetal gender by using free fetal DNA from maternal plasma. Prenatal Diagnosis 2008;28(6):525-30.
11. Hwa HL, Ko TM, Yen ML, Chiang YL. Fetal gender determination using real-time quantitative polymerase chain reaction analysis of maternal plasma. Journal of the Formosan Medical Association-Taiwan Yi Zhi 2004;103(5):364-8.
12. Davalieva K, Dimcev P, Efremov GD, Plaseska-Karanfilska D. Non-invasive fetal sex determination using real-time PCR. J Matern Fetal Neonatal Med 2006;19(6):337-42.
13. Rijnders RJ, van der Schoot CE, Bossers B, de Vroede MA, Christiaens GC. Fetal sex determination from maternal plasma in pregnancies at risk for congenital adrenal hyperplasia. Obstetrics and Gynecology 2001;98(3):374-8.
14. Horinek A, Korabecna M, Panczak A, Ulcova Gallova Z, Nouzova K, Calda P, Hancarova M. Cell-free fetal DNA in maternal plasma during physiological single male pregnancies: Methodology issues and kinetics. Fetal Diagnosis and Therapy 2008;24(1):15-21.
15. Landy HJ, Keith LG. The vanishing twin: a review. Human reproduction update 1998;4(2):177-83.
16. Stanghellini I, Bertorelli R, Capone L, Mazza V, Neri C, Percesepe A, Forabosco A. Quantitation of fetal DNA in maternal serum during the first trimester of pregnancy by the use of a DAZ repetitive probe. Molecular Human Reproduction 2006;12(9):587-91.
17. Zimmermann B, El-Sheikhah A, Nicolaides K, Holzgreve W, Hahn S. Optimized real-time quantitative PCR measurement of male fetal DNA in maternal plasma. Clinical Chemistry 2005;51(9):1598-604.
18. Viera AJ, Garrett JM. Understanding interobserver agreement: the kappa statistic. Family Medicine 2005;37(5):360-3.