Localisation and quantification of benzalkonium chloride in eye tissue by TOF-SIMS imaging and liquid chromatography mass spectrometry

Analytical and Bioanalytical Chemistry

Volumn 405, Issue 12, 2013, Pages 4039-4049

  Desbenoit, Nicolas ^a,b,c   Schmitz Afonso, Isabelle ^a   Baudouin, Christophe ^b,d,e,f   Laprévote, Olivier ^f,g   Touboul, David ^a   Brignole Baudouin, Françoise ^a,b,c,g   Brunelle, Alain ^a  

^a CNRS   (France)

^b INSERM   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d CENTRE HOSPITALIER NATIONAL D OPHTALMOLOGIE DES QUINZE VINGTS   (France)

^e LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^f ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^g FACULTÉ DES SCIENCES PHARMACEUTIQUES ET BIOLOGIQUES   (France)

Author keywords

Benzalkonium chloride .DDMAC; Glaucoma; LC MS; Mass spectrometry imaging; TOF SIMS

Indexed keywords

CHLORINE COMPOUNDS; DRUG PRODUCTS; IONS; OPHTHALMOLOGY; ORGANIC POLYMERS; SECONDARY ION MASS SPECTROMETRY;

BENZALKONIUM CHLORIDE; GLAUCOMA; LC-MS; MASS-SPECTROMETRY IMAGING; TOF SIMS;

LIQUID CHROMATOGRAPHY;

BENZALKONIUM; PRESERVATIVE;

AGED; ANIMAL; ARTICLE; CHEMISTRY; CONJUNCTIVA; ELECTROSPRAY MASS SPECTROMETRY; EYE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; MIDDLE AGED; RABBIT; REPRODUCIBILITY;

AGED; ANIMALS; BENZALKONIUM COMPOUNDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CONJUNCTIVA; EYE; HUMANS; MIDDLE AGED; PRESERVATIVES, PHARMACEUTICAL; RABBITS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROMETRY, MASS, SECONDARY ION;

EID: 84886851161     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-013-6811-7     Document Type: Article

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