Mycobacterium tuberculosis infection in rhesus monkeys (Macaca mulatta) and evaluation of ESAT-6 and CFP10 as immunodiagnostic antigens

Experimental Animals

Volumn 62, Issue 4, 2013, Pages 281-293

  Min, Fangui ^a   Zhang, Yu ^a   Pan, Jinchun ^a   Wang, Jing ^a   Yuan, Wen ^a  

^a Guangdong Laboratory Animals Monitoring Institute   (China)

Author keywords

Infection; Mycobacterium tuberculosis; Rhesus monkeys (Macaca mulatta); Serodiagnostic antigen

Indexed keywords

CULTURE FILTRATE PROTEIN 10; EARLY SECRETORY ANTIGENIC TARGET 6; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12P40; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; COLONY FORMING UNIT; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; DISEASE MODEL; EVALUATION RESEARCH; EXPERIMENTAL MONKEY; HISTOPATHOLOGY; IMMUNE RESPONSE; LEUKOCYTE COUNT; NONHUMAN; OBSERVATIONAL STUDY; PROTEIN BLOOD LEVEL; RHESUS MONKEY; SERODIAGNOSIS; TUBERCULIN TEST; TUBERCULOSIS;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BIOLOGICAL MARKERS; DISEASE MODELS, ANIMAL; HUMANS; MACACA MULATTA; MONKEY DISEASES; MYCOBACTERIUM TUBERCULOSIS; PEPTIDE FRAGMENTS; RECOMBINANT FUSION PROTEINS; SEROLOGIC TESTS; TUBERCULOSIS;

EID: 84886849079     PISSN: 13411357     EISSN: None     Source Type: Journal    
DOI: 10.1538/expanim.62.281     Document Type: Article

References (25)

1. Anacker, R.L., Brehmer, W., Barclay, W.R., Leif, W.R., Ribi, E., Simmons, J.H., and Smith, A.W. 1972. Superiority of intravenously administered BCg and BCg cell walls in protecting rhesus monkeys (Macaca mulatta) against airborne tuberculosis. Z. Immunitatsforsch. Exp. Klin. Immunol. 143: 363-376.
2. Barclay, W.R., Busey, W.M., Dalgard, D.W., good, R.C., Janicki, B.W., Kasik, J.E., Ribi, E., Ulrich, C.E., and Wo-linsky, E. 1973. Protection of monkeys against airborne tuberculosis by aerosol vaccination with Bacillus Calmette-guerin. Am. Rev. Respir. Dis. 107: 351-358.
3. Brusasca, P.N., Peters, R.L., Motzel, S.L., Klein, H.J., and Gennaro, M.L. 2003. Antigen recognition by serum antibodies in non-human primates experimentally infected with Mycobacterium tuberculosis. Comp. Med. 53: 165-172.
4. Capuano, S.V., Croix, D.A., Pawar, S., Zinovik, A., Myers, A., Lin, P.L., Bissel, S., Fuhrman, C., Klein, E., and Flynn, J.L. 2003. Experimental Mycobacterium tuberculosis infection of cynomolgus macaques closely resembles the various manifestations of human M. tuberculosis infection. Infect. Immun. 71: 5831-5844.
5. CDC. 1991. Update: nonhuman primate importation. MMWR 40: 684-685, 691.
6. CDC. 1993. Tuberculosis in imported nonhuman primates: united States, June 1990-May 1993. MMWR 42: 572-576.
7. Chen, C.Y., huang, D., Wang, R.C., Shen, L., Zeng, G., Yao, S., Shen, Y., Halliday, L., Fortman, J., Mcallister, M., Estep, J., Hunt, R., Vasconcelos, D., Du, G., Porcelli, S.A., Larsen, M.H., Jacobs, W.R. Jr., haynes, B.F., Letvin, N.L., and Chen, Z.W. 2009. A Critical Role for CD8 T Cells in a nonhuman Primate Model of Tuberculosis. PLoS Pathog. 5: e1000392.
8. Cole, S.T., Brosch, R., Parkhill, J., garnier, T., Churcher, C., Harris, D., Gordon, S.V., Eiglmeier, K., Gas, S., Barry, C.E., Tekaia, F., Badcock, K., Basham, D., Brown, D., Chill-ingworth, T., Connor, R., Davies, R., Devlin, K., Feltwell, T., gentles, S., hamlin, n., holroyd, S., hornsby, T., Jagels, K., Krogh, A., McLean, J., Moule, S., Murphy, L., Oliver, K., Osborne, J., Quail, M.a., Rajandream, M.A., Rogers, J., Rutter, S., Seeger, K., Skelton, J., Squares, R., Squares, S., Sulston, J.E., Taylor, K., Whitehead, S., and Barrell, B.G. 1998. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393: 537-544.
9. Corcoran, K.D. and Thoen, C.O. 1991. Application of an enzyme immunoassay for detecting antibodies in sera of Macaca fascicularis naturally exposed to Mycobacterium tuberculosis. J. Med. Primatol. 20: 404-408.
10. Garcia, M.A., Bouley, D.M., Larson, M.J., Lifand, B., Moorhead, R., Simkins, M.D., Borie, D.C., Tolwani, R., and Otto, G. 2004. Outbreak of Mycobacterium bovis in a conditioned colony of rhesus (Macaca mulatta) and cynomolgus (Macaca fascicularis) macaques. Comp. Med. 54: 578-584.
11. Garcia, M.A., Yee, J., Bouley, D.M., Moorhead, R., and Le-rche, N.W. 2004. Diagnosis of tuberculosis in macaques, using whole-blood in vitro interferon-gamma (PRiMagaM) testing. Comp. Med. 54: 86-92.
12. Garnier, T., Eiglmeier, K., Camus, J.C., Medina, N., Man-soor, h., Pryor, M., Duthoy, S., grondin, S., Lacroix, C., Monsempe, C., Simon, S., harris, B., atkin, R., Doggett, J., Mayes, R., Keating, L., Wheeler, P.R., Parkhill, J., Barrell, B.G., Cole, S.T., Gordon, S.V., and Hewinson, R.G. 2003. The complete genome sequence of Mycobacterium bovis. Proc. Natl. Acad. Sci. U.S.A. 100: 7877-7882.
13. Gormus, B.J., Blanchard, J.L., Alvarez, X.H., and Didier, P.J. 2004. Evidence for a rhesus monkey model of asymptomatic tuberculosis. J. Med. Primatol. 33: 134-145.
14. Gupta, U.D. and Katoch, V.M. 2005. Animal models of tuberculosis. Tuberculosis (Edinb) 85: 277-293.
15. Kanaujia, G.V., Motzel, S., Garcia, M.A., Andersen, P., and Gennaro, M.L. 2004. Recognition of ESAT-6 sequences by antibodies in sera of tuberculous nonhuman primates. Clin. Diagn. Lab. Immunol. 11: 222-226.
16. Kaufmann, A.F. 1971. A program for surveillance of nonhu-man primate disease. Lab. Anim. Sci. 21: 1061-1067.
17. Kunnath-Velayudhan, S., Davidow, A.L., Wang, H.Y., Molina, D.M., Huynh, V.T., Salamon, H., Pine, R., Michel, G., Perkins, M.D., Xiaowu, L., Felgner, P.L., Flynn, J.L., Catan-zaro, A., and Gennaro, M.L. 2012. Proteome-scale antibody responses and outcome of mycobacterium tuberculosis infection in nonhuman primates and in tuberculosis patients. J. Infect. Dis. 206: 697-705.
18. Langermans, J.A.M., Doherty, T.M., Vervenne, R.A.W., van der Laan, T., Lyashchenko, K., Greenwald, R., Agger, E.M., Aagaard, C., Weiler, H., van Soolingen, D., Dalemans, W., Thomas, A.W., and Andersen, P. 2005. Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6. Vaccine 23: 2740-2750.
19. National Research Council. 2010. Guide for the Care and use of Laboratory animals, 8th national academy Press, Washington, DC.
20. O'Reilly, L.M. 1995. Tuberculin skin tests: sensitivity and specifcity, pp. 85-91. In: Mycobacterium bovis infection in animals and humans. (Thoen, C.O., and Steele, J.h., eds.), iowa State university Press, ames.
21. Smithburn, K.C., Sabin, F.R., and Hummel, L.E. 1937. Hae-matological studies in experimental tuberculosis: variations in the blood cells of rabbits inoculated with cultures differing in virulence. Am. Rev. Tuberc. 36: 673-691.
22. Sugawara, I., Li, Z., Sun, L., Udagawa, T., and Taniyama, T. 2007. Recombinant BCg Tokyo (ag85a) protects cynomol-gus monkeys (Macaca fascicularis) infected with h37Rv Mycobacterium tuberculosis. Tuberculosis (Edinb) 87: 518-525.
23. Sugawara, I., Sun, L., Mizuno, S., and Taniyama, T. 2009. Protective efficacy of recombinant BCG Tokyo (Ag85A) in rhesus monkeys (Macaca mulatta) infected intratracheally with h37Rv Mycobacterium tuberculosis. Tuberculosis (Ed-inb) 89: 62-67.
24. Walsh, G.P., Tan, E.V., Dela Cruz, E.C., Abalos, R.M., Vil-lahermosa, L.G., Young, L.J., Cellona, R.V., Nazareno, J.B., and Horwitz, M.A. 1996. The Philippine cynomolgus monkey (Macaca fascicularis) provides a new nonhuman primate model of tuberculosis that resembles human disease. Nat. Med. 2: 430-436.
25. Zhang, J., Ye, Y.Q., Wang, Y., Mo, P.Z., Xian, Q.Y., Rao, Y., Bao, R., Dai, M., Liu, J.Y., Guo, M., Wang, X., huang, Z.X., Sun, L.H., Tang, Z.J., and Ho, W.Z. 2011. M. tuberculosis h37Rv infection of Chinese Rhesus Macaques. J. Neuroim-mune. Pharmacol. 6: 362-370.