A new bioactive diterpene glycoside from Molinaea retusa from the Madagascar dry forest

Natural Product Communications

Volumn 8, Issue 9, 2013, Pages 1201-1203

  Eaton, Alexander L ^a   Harinantenaina, Liva ^a   Brodie, Peggy J ^a   Cassera, Maria B ^a   Bowman, Jessica D ^a   Callmander, Martin W ^b   Randrianaivo, Richard ^b   Rakotondrajaona, Roland ^c   Rakotobe, Etienne ^c   Rasamison, Vincent F ^c   Kingston, David G I ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^b MISSOURI BOTANICAL GARDEN   (Madagascar)

^c Centre National d'Application des Recherches Pharmaceutiques   (Madagascar)

Author keywords

Antiplasmodial; Antiproliferative; Diterpene; Molinaea retusa; Saponin

Indexed keywords

2'',3'',4'',6' DE O ACETYLCUPACINOSIDE; 6 DE O ACETYLCUPACINOSIDE; ANTIMALARIAL AGENT; ANTINEOPLASTIC AGENT; ANTISPOROZOAL AGENT; CUPACINOSIDE; CYTOTOXIC AGENT; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL LINE; COLUMN CHROMATOGRAPHY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG MECHANISM; DRUG STRUCTURE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIQUID LIQUID EXTRACTION; MEDICINAL PLANT; MOLINAEA RETUSA; NONHUMAN; PLASMODIUM FALCIPARUM;

PLASMODIUM FALCIPARUM; RETUSA; SAPINDACEAE;

EID: 84886811994     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: 10.1177/1934578x1300800903     Document Type: Article

References (14)

1. Biodiversity Conservation and Drug Discovery in Madagascar, Part 57. For Part 56, see Liu Y, Harinantenaina L, Brodie PJ, Slebodnick C, Callmander MW, Rakotondrajaona R, Rakotobe E, Rasamison VE, TenDyke K, Shen Y, Kingston DGI. (2013) Structure elucidation of antiproliferative bisbenzylisoquinoline alkaloids from Anisocycla groodidieri from the Madagascar dry forest. Magnetic Resonance in Chemistry, in press.
2. Mabberley DJ. (1997) The Ploot-book: a Portable Dictionary of the Vascular Plants. 2nd edition, Cambridge, Cambridge University Press.
3. (a) Gachet MS, Kunert O, Kaiser M, Brun R, Zehl M, Keller W, Munoz RA, Bauer R, Schuchly W. (2011) Antiparasitic compounds from Cupania cinerea with activities against Plasmodium falciparum and Trypanosoma brucei rhodesiense. Journal of Natural Products, 74, 559-566;
4. (b) Cao S, Brodie P, Callmander M, Randrianaivo R, Razafitsalama J, Rakotobe E, Rasamison VE, TenDyke K, Shen Y, Suh EM, Kingston DGI. (2009) Antiproliferative triterpenoid saponins of Dodonaea viscosa from the Madagascar dry forest. Journal of Natural Products, 72, 1705-1707;
5. (c) Cavalcanti SBT, Teles HL, Silva DHS, Furlan M, Young MCM, Bolzani VS. (2001) New tetra-acetylated oligosaccharide diterpene from Cupania vernalis. Journal of the Brazilian Chemical Society, 12, 413-416;
6. (d) Fu H, Quo Y, Li W, Dou D, Kang T, Koike K. (2010) A new angeloylated triterpenoid saponin from the husks of Xanthoceras sorbifolia Bunge. Journal of Natural Medicines, 64, 80-84;
7. (e) Ito A, Chai HB, Kardono LB, Setowati FM, Afriastini JJ, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. (2004) Saponins from the bark of Nephelium maingayi. Journal of Natural Products, 67, 201-205;
8. (f) de Oliveira SQ, de Almeida MTR, Maraslis F, Silva IT, Sincero TCM, Palermo JA, Cabrera GM, Caro MSB, Simões CMO, Schenkel EP. (2012) Isolation of three new ent-labdane diterpenes from Dodonaea viscosa Jacquin (Sapindaceae): Preliminary evaluation of antiherpes activity. Phytochemistry Letters, 5, 500-505;
9. (g) Tantangmo F, Lenta BN, Ngouela S, Kamdem LM, Weniger B, Tsamo E, Lobstein A, Vonthron-Senecheau C. (2010) New sphingolipids and other constituents of Pancovia laurentii. Helvetica Chimica Acta, 93, 2210-2217;
10. (h) Zhang LB, Ji J, Lei C, Wang HY, Zhao QS, Hou AJ. (2012) Isoprenylated flavonoid and adipogenesis-promoting constituents of Dodonaea viscosa. Journal of Natural Products, 75, 699-706.
11. Eberhard B, Voelter W. (1987) Carbon-13 NMR Spectroscopy: High Resolution Methods andApplications in Organic Chemistry and Biochemistry. 3rd edition, Weinheim, FRG, VCH Publishers.
12. Cao S, Brodie PJ, Miller JS, Randrianaivo R, Ratovoson F, Birkinshaw C, Andriantsiferana R, Rasamison VE, Kingston DGI. (2007) Antiproliferative xanthones of Terminalia calcicola from the Madagascar rain forest. Journal of Natural Products, 70, 679-681.
13. Louie KG, Bebrens BC, Kinsella TJ, Hamilton TC, Grotzinger KR, McKoy WM, Winker MA, Ozols RF. (1985) Radiation survival parameters of antineoplastic drug-sensitive and -resistant human ovarian cancer cell lines and their modification by buthionine sulfoximine. Cancer Research, 45, 2110-2115.
14. Harinantenaina L, Bowman JD, Brodie PJ, Slebodnick C, Callmander MW, Rakotobe E, Randrianaivo R, Rasamison VE, Gorka A, Roepe PD, Cassera MB, Kingston DG. (2013) Antiproliferative and antiplasmodial dimeric phloroglucinols from Mallotus oppositifolius from the Madagascar dry forest. Journal of Natural Products, 76, 388-393.