Analytics of the therapeutic peptide aviptadil by sheathless CE-MS and comparison with nanoRP-HPLC-MS

Journal of Pharmaceutical and Biomedical Analysis

Volumn 88, Issue , 2014, Pages 477-482

  Gross, Peter C ^a   Burkart, Sonja C ^a,c   Müller, Rolf ^a,b,c  

^a PomBioTech GmbH   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

NanoLC MS; Quality control; Sheathless CE MS; Therapeutic peptides; Unspecific peptide adsorption

Indexed keywords

VASOACTIVE INTESTINAL POLYPEPTIDE;

ADSORPTION; ARTICLE; CAPILLARY ELECTROPHORESIS; COMPARATIVE STUDY; ELECTROPHORETIC MOBILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMIT OF DETECTION; MASS SPECTROMETER; MASS SPECTROMETRY; MEASUREMENT REPEATABILITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PURIFICATION; QUALITY CONTROL;

NANOLC-MS; QUALITY CONTROL; SHEATHLESS CE-MS; THERAPEUTIC PEPTIDES; UNSPECIFIC PEPTIDE ADSORPTION;

ADSORPTION; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG COMBINATIONS; ELECTROCHEMISTRY; ELECTROPHORESIS, CAPILLARY; HUMANS; LIGANDS; LIMIT OF DETECTION; LINEAR MODELS; MASS SPECTROMETRY; OXYGEN; PEPTIDES; PHENTOLAMINE; QUALITY CONTROL; REPRODUCIBILITY OF RESULTS; SILICON DIOXIDE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; VASOACTIVE INTESTINAL PEPTIDE;

EID: 84886788121     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2013.09.024     Document Type: Article

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