Validating a widely used measure of frailty: Are all sub-components necessary? Evidence from the whitehall ii cohort study

Age

Volumn 35, Issue 4, 2013, Pages 1457-1465

  Bouillon, Kim ^a   Sabia, Severine ^a   Jokela, Markus ^a,b   Gale, Catharine R ^c,d   Singh Manoux, Archana ^a,e,f   Shipley, Martin J ^a   Kivimäki, Mika ^a,g   Batty, G David ^a,d  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e CENTRE FOR RESEARCH IN EPIDEMIOLOGY AND POPULATION HEALTH   (France)

^f ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^g FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

Author keywords

Cohort study; Frail elderly; Frailty; Hospitalization; Prediction; Validation

Indexed keywords

ADULT; AGE; AGED; ARTICLE; COHORT ANALYSIS; EXHAUSTION; FEMALE; FRAIL ELDERLY; FUNCTIONAL ASSESSMENT; GENDER; GRIP STRENGTH; HAZARD RATIO; HOSPITALIZATION; HUMAN; MALE; MEDICAL RECORD REVIEW; PHYSICAL ACTIVITY; PHYSICAL CAPACITY; PHYSICAL PERFORMANCE; VALIDATION PROCESS; WALKING SPEED; WEIGHT REDUCTION; AGING; COMPARATIVE STUDY; CONFIDENCE INTERVAL; DISABLED PERSON; EPIDEMIOLOGY; GERIATRIC ASSESSMENT; INCIDENCE; MIDDLE AGED; PHYSIOLOGY; PROCEDURES; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; SOLDIER; STATISTICS AND NUMERICAL DATA; UNITED KINGDOM; VALIDATION STUDY; VERY ELDERLY; WALKING; METHODOLOGY; STATISTICS;

ADULT; AGED; AGED, 80 AND OVER; AGING; CONFIDENCE INTERVALS; DISABLED PERSONS; FEMALE; FRAIL ELDERLY; GERIATRIC ASSESSMENT; GREAT BRITAIN; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MILITARY PERSONNEL; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; WALKING; WEIGHT LOSS;

EID: 84886785308     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-012-9446-2     Document Type: Article

References (37)

1. Ainsworth BE, Haskell WL, Leon AS, Jacobs DR Jr, Montoye HJ, Sallis JF, Paffenbarger RS Jr (1993) Compendium of physical activities: classification of energy costs of human physical activities. Med Sci Sports Exerc 25:71-80
2. Al Snih S, Graham JE, Ray LA, Samper-Ternent R, Markides KS, Ottenbacher KJ (2009) Frailty and incidence of activities of daily living disability among older Mexican Americans. J Rehabil Med 41:892-897
3. Avila-Funes JA, Helmer C, Amieva H, Barberger-Gateau P, Le Goff M, Ritchie K, Portet F, Carriere I, Tavernier B, Gutierrez-Robledo LM, Dartigues JF (2008) Frailty among community-dwelling elderly people in France: the threecity study. J Gerontol A Biol Sci Med Sci 63:1089-1096
4. Bandeen-Roche K, Xue QL, Ferrucci L, Walston J, Guralnik JM, Chaves P, Zeger SL, Fried LP (2006) Phenotype of frailty: characterization in the women's health and aging studies. J Gerontol A Biol Sci Med Sci 61:262-266
5. Boyd CM, Xue QL, Simpson CF, Guralnik JM, Fried LP (2005) Frailty, hospitalization, and progression of disability in a cohort of disabled older women. Am J Med 118:1225-1231
6. Boyd CM, Ricks M, Fried LP, Guralnik JM, Xue QL, Xia J, Bandeen-Roche K (2009) Functional decline and recovery of activities of daily living in hospitalized, disabled older women: the Women's Health and Aging Study I. J Am Geriatr Soc 57:1757-1766
7. Cawthon PM, Marshall LM, Michael Y, Dam TT, Ensrud KE, Barrett-Connor E, Orwoll ES, Osteoporotic Fractures in Men Research Group (2007) Frailty in older men: prevalence, progression, and relationship with mortality. J Am Geriatr Soc 55:1216-1223
8. Cox DR (1972) Regression models and life-tables. J R Stat Soc Ser B (Methodol) 34:187-220
9. de Vries NM, Staal JB, van Ravensberg CD, Hobbelen JS, Olde Rikkert MG, Nijhuis-van der Sanden MW (2011) Outcome instruments to measure frailty: a systematic review. [Review]. Ageing Res Rev 10:104-114
10. Ensrud KE, Ewing SK, Taylor BC, Fink HA, Stone KL, Cauley JA, Tracy JK, Hochberg MC, Rodondi N, Cawthon PM, for the Study of Osteoporotic Fractures Research Group (2007) Frailty and risk of falls, fracture, and mortality in older women: the study of osteoporotic fractures. J Gerontol A Biol Sci Med Sci 62:744-751
11. Ensrud KE, Ewing SK, Taylor BC, Fink HA, Cawthon PM, Stone KL, Hillier TA, Cauley JA, Hochberg MC, Rodondi N, Tracy JK, Cummings SR (2008) Comparison of 2 frailty indexes for prediction of falls, disability, fractures, and death in older women. Arch Intern Med 168:382-389
12. Faber MJ, Bosscher RJ, Chin APM, van Wieringen PC (2006) Effects of exercise programs on falls and mobility in frail and pre-frail older adults: a multicenter randomized controlled trial. Arch Phys Med Rehabil 87:885-896
13. Fairhall N, Sherrington C, Kurrle SE, Lord SR, Cameron ID (2011) ICF participation restriction is common in frail, community-dwelling older people: an observational crosssectional study. Physiotherapy 97:26-32
14. Folsom AR, Caspersen CJ, Taylor HL, Jacobs DR Jr, Luepker RV, Gomez-Marin O, Gillum RF, Blackburn H (1985) Leisure time physical activity and its relationship to coronary risk factors in a population-based sample. The Minnesota Heart Survey. Am J Epidemiol 121:570-579
15. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G, McBurnie MA, Cardiovascular Health Study Collaborative Research Group (2001) Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 56:M146-M156
16. Harrell FE Jr, Lee KL, Mark DB (1996) Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med 15:361-387
17. Kaplan EL, Meier P (1958) Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481
18. Kenny AM, Boxer RS, Kleppinger A, Brindisi J, Feinn R, Burleson JA (2010) Dehydroepiandrosterone combined with exercise improves muscle strength and physical function in frail older women. J Am Geriatr Soc 58:1707-1714
19. Kiely DK, Cupples LA, Lipsitz LA (2009) Validation and comparison of two frailty indexes: the MOBILIZE Boston study. J Am Geriatr Soc 57:1532-1539
20. Kulminski AM, Ukraintseva SV, Kulminskaya IV, Arbeev KG, Land K, Yashin AI (2008) Cumulative deficits better characterize susceptibility to death in elderly people than phenotypic frailty: lessons from the Cardiovascular Health Study. J Am Geriatr Soc 56:898-903
21. Marmot M, Brunner E (2005) Cohort Profile: the Whitehall II study. Int J Epidemiol 34:251-256
22. Newson RB (2010) Comparing the predictive power of survival models using Harrell's c or Sommers' D. Stata J 10:339-358
23. Peterson MJ, Sloane R, Cohen HJ, Crowley GM, Pieper CF, Morey MC (2007) Effect of telephone exercise counseling on frailty in older veterans: project LIFE. Am J Mens Health 1:326-334
24. Peto R, Peto J (1972) Asymptotically efficient rank invariant test procedures. J R Stat Soc Ser A (Gen) 135:185-207
25. Radloff LS (1977) The CES-D Scale. Appl Psychol Meas 1:385-401
26. Rochat S, Cumming RG, Blyth F, Creasey H, Handelsman D, Le Couteur DG, Naganathan V, Sambrook PN, Seibel MJ, Waite L (2010) Frailty and use of health and community services by community-dwelling older men: the Concord Health and Ageing in Men Project. Age Ageing 39:228-233
27. Rockwood K (2005) What would make a definition of frailty successful? Age Ageing 34:432-434
28. Romero-Ortuno R, Walsh CD, Lawlor BA, Kenny RA (2010) A frailty instrument for primary care: findings from the Survey of Health, Ageing and Retirement in Europe (SHARE). BMC Geriatr 10:57
29. Rothman MD, Leo-Summers L, Gill TM (2008) Prognostic significance of potential frailty criteria. J Am Geriatr Soc 56:2211-2216
30. Seematter-Bagnoud L, Santos-Eggimann B, Rochat S, Martin E, Karmaniola A, Aminian K, Piot-Ziegler C, Bula CJ (2010) Vulnerability in high-functioning persons aged 65 to 70 years: the importance of the fear factor. Aging Clin Exp Res 22:212-218
31. Singh-Manoux A, Hillsdon M, Brunner E, Marmot M (2005) Effects of physical activity on cognitive functioning in middle age: evidence from the Whitehall II prospective cohort study. Am J Public Health 95:2252-2258
32. Srinivas-Shankar U, Roberts SA, Connolly MJ, O'Connell MD, Adams JE, Oldham JA, Wu FC (2010) Effects of testosterone on muscle strength, physical function, body composition, and quality of life in intermediate-frail and frail elderly men: a randomized, double-blind, placebocontrolled study. J Clin Endocrinol Metab 95:639-650
33. Sternberg SA, Wershof SA, Karunananthan S, Bergman H, Clarfield AM (2011) The identification of frailty: a systematic literature review. [Review]. J Am Geriatr Soc 59:2129-2138
34. Tan EJ, Rebok GW, Yu Q, Frangakis CE, Carlson MC, Wang T, Ricks M, Tanner EK, McGill S, Fried LP (2009) The longterm relationship between high-intensity volunteering and physical activity in older African American women. J Gerontol B Psychol Sci Soc Sci 64:304-311
35. The NHS Information Centre for health and social care (2011) Hospital Episode Statistics (HES) http://www.hesonli ne.nhs.uk. Accessed 25 January 2011
36. Wong CH, Weiss D, Sourial N, Karunananthan S, Quail JM, Wolfson C, Bergman H (2010) Frailty and its association with disability and comorbidity in a community-dwelling sample of seniors in Montreal: a cross-sectional study. Aging Clin Exp Res 22:54-62
37. Woods NF, LaCroix AZ, Gray SL, Aragaki A, Cochrane BB, Brunner RL, Masaki K, Murray A, Newman AB, Women's Health Initiative (2005) Frailty: emergence and consequences in women aged 65 and older in the Women's Health Initiative Observational Study. J Am Geriatr Soc 53:1321-1330