Efficacy and safety of rotigotine in Japanese patients with restless legs syndrome: A phase 3, multicenter, randomized, placebo-controlled, double-blind, parallel-group study

Sleep Medicine

Volumn 14, Issue 11, 2013, Pages 1085-1091

  Inoue, Yuichi ^a   Shimizu, Tetsuo ^b   Hirata, Koichi ^c   Uchimura, Naohisa ^d   Ishigooka, Jun ^e   Oka, Yasunori ^f   Ikeda, Junji ^g   Tomida, Takayuki ^g   Hattori, Nobutaka ^h   Kousaka, Masako ⁱ   Kanno, Osamu ⁱ   Kanbayashi, Takashi ⁱ   Kaneko, Yasuyuki ⁱ   Katayama, Souichi ⁱ   Hatano, Taku ⁱ   Murata, Miho ⁱ   Nakajima, Tohru ⁱ   Endo, Takurou ⁱ   Shibui, Kayo ⁱ   Hayashida, Kenichi ⁱ   Tada, Kouji ⁱ   Komagamine, Masazumi ⁱ   Muraoka, Hideo ⁱ   Miki, Kazuhira ⁱ   Sasaki, Mitsuo ⁱ   Tanaka, Haruhito ⁱ   Sasanabe, Ryuujiro ⁱ   Kume, Akito ⁱ   Koike, Shigefumi ⁱ   Yamada, Naoto ⁱ   Tanaka, Toshihiko ⁱ   Emura, Narutsugu ⁱ   Egawa, Isao ⁱ   Kuroda, Kenji ⁱ   Kodama, Mitsuo ⁱ   Taniguchi, Mitsutaka ⁱ   Kyoutani, Kyouko ⁱ   Hiwatani, Yasuhiro ⁱ   Nomoto, Masahiro ⁱ   Kawada, Seiichi ⁱ   Hashidume, Yuuji ⁱ   Sasagasako, Naokazu ⁱ   Ariyoshi, You ⁱ   Yamaguchi, Yuji ⁱ   Tsuda, Tohru ⁱ   Ikegami, Azusa ⁱ   Tsuruta, Kazuhito ⁱ   Takaoka, Toshio ⁱ   Touyama, Kazuyo ⁱ   more..

^a TOKYO MEDICAL UNIVERSITY   (Japan)

^b AKITA UNIVERSITY   (Japan)

^c DOKKYO MEDICAL UNIVERSITY   (Japan)

^d KURUME UNIVERSITY   (Japan)

^e TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^f EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^h JUNTENDO UNIVERSITY HOSPITAL   (Japan)

ⁱ NONE

Author keywords

Clinical trial; International Restless Legs Study Group rating scale; Japan; Pittsburgh Sleep Quality Index; Restless legs syndrome; Rotigotine

Indexed keywords

PLACEBO; ROTIGOTINE;

APPLICATION SITE REACTION; ARTICLE; CLINICAL EFFECTIVENESS; CLINICAL SKIN REACTION; CONTROLLED STUDY; CONTUSION; DISEASE SEVERITY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; EDEMA; ERYTHEMA; FEMALE; GASTRITIS; HEADACHE; HUMAN; IDIOPATHIC DISEASE; INSOMNIA; INTERNATIONAL RESTLESS LEGS SYNDROME STUDY GROUP RATING SCALE; JAPANESE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; OUTCOME ASSESSMENT; PAPULE; PHASE 3 CLINICAL TRIAL; PITTSBURGH SLEEP QUALITY INDEX; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; RESTLESS LEGS SYNDROME; RHINOPHARYNGITIS; SEROPAPULE; SKIN IRRITATION; SOMNOLENCE; VOMITING;

CLINICAL TRIAL; INTERNATIONAL RESTLESS LEGS STUDY GROUP RATING SCALE; JAPAN; PITTSBURGH SLEEP QUALITY INDEX; RESTLESS LEGS SYNDROME; ROTIGOTINE;

AGED; ASIAN CONTINENTAL ANCESTRY GROUP; DOPAMINE AGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MIDDLE AGED; PLACEBOS; RESTLESS LEGS SYNDROME; SEVERITY OF ILLNESS INDEX; SLEEP; SLEEP INITIATION AND MAINTENANCE DISORDERS; TETRAHYDRONAPHTHALENES; THIOPHENES;

EID: 84886774958     PISSN: 13899457     EISSN: 18785506     Source Type: Journal    
DOI: 10.1016/j.sleep.2013.07.007     Document Type: Article

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