Therapy with autologous adipose-derived regenerative cells for the care of chronic ulcer of lower limbs in patients with peripheral arterial disease

Journal of Surgical Research

Volumn 185, Issue 1, 2013, Pages 36-44

  Marino, Gerardo ^a   Moraci, Marco ^a   Armenia, Emilia ^a   Orabona, Consiglia ^a   Sergio, Renato ^a   De Sena, Gabriele ^a   Capuozzo, Vincenza ^a   Barbarisi, Manlio ^a   Rosso, Francesco ^a   Giordano, Giovanni ^a   Iovino, Francesco ^a   Barbarisi, Alfonso ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

Adipose stem cells; Arterial disease; Chronic ulcer

Indexed keywords

ADIPOSE DERIVED STEM CELL; ADULT; AGED; ANKLE BRACHIAL INDEX; ARTERY DISEASE; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; CELL REGENERATION; CELL VIABILITY; CLINICAL ARTICLE; DEBRIDEMENT; EPITHELIZATION; FEASIBILITY STUDY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; HUMAN TISSUE; LEG ULCER; MALE; MEDICAL DEVICE; PAIN; PATIENT MONITORING; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PRIORITY JOURNAL; ULCER HEALING; WOUND CARE;

ADIPOSE STEM CELLS; ARTERIAL DISEASE; CHRONIC ULCER;

ADIPOSE TISSUE; AGED; ANKLE BRACHIAL INDEX; CHRONIC DISEASE; COMBINED MODALITY THERAPY; FEMALE; FLOW CYTOMETRY; GRAFT SURVIVAL; HUMANS; HYPERBARIC OXYGENATION; LEG ULCER; MALE; MIDDLE AGED; PERIPHERAL ARTERIAL DISEASE; REGENERATION; STEM CELL TRANSPLANTATION; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME;

EID: 84886719871     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2013.05.024     Document Type: Article

References (14)

1. G.D. Gentzkow, S.D. Iwasaki, and K.S. Hershon Use of dermagraft, a cultured human dermis, to treat diabetic foot ulcers Diabetes Care 19 1996 350
2. J.R. Hanft, and M.S. Surprenant Healing of chronic foot ulcers in diabetic patients treated with a human fibroblast derived dermis J Foot Ankle Surg 41 2002 291
3. S. Akita, H. Yoshimoto, and K. Akino Early experiences with stem cells in treating chronic wounds Clin Plast Surg 39 2012 281
4. H. Mizuno, and M. Nambu Adipose-derived stem cells for skin regeneration Methods Mol Biol 702 2011 453
5. K. Lin, Y. Matsubara, and Y. Masuda Characterization of adipose tissue-derived cells isolated with the Celution system Cytotherapy 10 2008 417
6. D. Xu, L. Zou, and Y. Xing Diagnostic value of ankle-brachial index in peripheral arterial disease: a meta-analysis Can J Cardiol 29 2013 492
7. C. Alfano, M. Angelisanti, C. Calzoni, F. Somma, and S. Chiummariello Treatment of ulcer and difficult wounds of the lower limbs: our experience Ann Ital Chir 83 2012 135
8. W. Wagner, F. Wein, and A. Seckinger Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood Exp Hematol 33 2005 1402
9. J. Mitchell, K. Micintosh, and S. Zavonic Immunophenotype of human adipose-derived cells: temporal changes in stromal-associated and stem cell-associated markers Stem Cells 24 2006 376
10. S. Akita, K. Akino, A. Hirano, A. Ohtsuru, and S. Yamashita Noncultured autologous adipose-derived stem cells therapy for chronic radiation injury Stem Cells Int 2010 2010 532704
11. V. Planat-Benard, J.S. Silvestre, and B. Cousin Plasticity of human adipose lineage cells toward endothelial cells: physiological and therapeutic perspectives Circulation 109 2004 656
12. G. Marino, F. Rosso, and P. Ferdinando Growth and endothelial differentiation of adipose stem cells on polycaprolactone J Biomed Mater Res A 100 2012 543
13. G. Rigotti, A. Marchi, and M. Galiè Clinical treatment of radiotherapy tissue damage by lipoaspirate transplant: a healing process mediated by adipose-derived adult stem cells Plast Reconstr Surg 119 2007 1409
14. A.C. Boquest, A. Shahdadfar, and K. Fronsdal Isolation and transcription profiling of purified uncultured human stromal stem cells: alteration of gene expression after in vitro cell culture Mol Biol Cell 16 2005 1131