Synthesis of combretastatin A4 analogues on steroidal framework and their anti-breast cancer activity

Journal of Steroid Biochemistry and Molecular Biology

Volumn 137, Issue , 2013, Pages 332-344

  Parihar, Swati ^a   Kumar, Amit ^b   Chaturvedi, Amit K ^a   Sachan, Naresh Kumar ^a   Luqman, Suaib ^a   Changkija, Bendangla ^b   Manohar, Murli ^b   Prakash, Om ^a   Chanda, D ^a   Khan, Feroz ^a   Chanotiya, C S ^a   Shanker, Karuna ^a   Dwivedi, Anila ^b   Konwar, Rituraj ^b   Negi, Arvind S ^a  

^a CSIR CENTRAL INSTITUTE OF MEDICINAL AND AROMATIC PLANTS   (India)

^b CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Acute oral toxicity; Antiestrogenicity; Breast cancer; Combretastatin A4; Estrogenicity; Tubulin polymerization inhibition

Indexed keywords

COMBRETASTATIN A4; GALLIC ACID; PACLITAXEL; PODOPHYLLOTOXIN; STEROID; STILBENE DERIVATIVE; TAMOXIFEN;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CELL CYCLE; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MICROTUBULE; MOUSE; NONHUMAN;

ACUTE ORAL TOXICITY; ANTIESTROGENICITY; BREAST CANCER; COMBRETASTATIN A4; ESTROGENICITY; TUBULIN POLYMERIZATION INHIBITION;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STEROIDS; STILBENES;

MUS;

EID: 84886718470     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2013.02.009     Document Type: Article

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