EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis

Acta Neuropathologica

Volumn 125, Issue 5, 2013, Pages 683-698

  Talasila, Krishna M ^a   Soentgerath, Anke ^a,b   Euskirchen, Philipp ^a   Rosland, Gro V ^a   Wang, Jian ^a   Huszthy, Peter C ^a   Prestegarden, Lars ^a,c   Skaftnesmo, Kai Ove ^a   Sakariassen, Per Øystein ^a   Eskilsson, Eskil ^a   Stieber, Daniel ^d   Keunen, Olivier ^a,d   Brekka, Narve ^a   Moen, Ingrid ^a   Nigro, Janice M ^a   Vintermyr, Olav K ^e   Lund Johansen, Morten ^a,c   Niclou, Simone ^d   Mørk, Sverre J ^e   Enger, Per Øyvind ^a,c   Bjerkvig, Rolf ^a,d   Miletic, Hrvoje ^a,e   more..

^a UNIVERSITY OF BERGEN   (Norway)

^b KRANKENHAUS MERHEIM   (Germany)

^c HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^d LUXEMBOURG INSTITUTE OF HEALTH   (Luxembourg)

^e HAUKELAND UNIVERSITY HOSPITAL   (Norway)

Author keywords

EGFR amplification; Glioblastoma; Invasion

Indexed keywords

CD133 ANTIGEN; CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; NESTIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTION FACTOR TWIST; VIMENTIN; ANTINEOPLASTIC AGENT; MONOCLONAL ANTIBODY;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BIOPSY; BRAIN TISSUE; CANCER INHIBITION; CARCINOGENESIS; CELL INFILTRATION; CONTROLLED STUDY; EMBRYO; EPITHELIAL MESENCHYMAL TRANSITION; GENE ACTIVATION; GENE ACTIVITY; GENE AMPLIFICATION; GENE EXPRESSION; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRACRANIAL DRUG ADMINISTRATION; NONHUMAN; OSMOTIC MINIPUMP; PRIORITY JOURNAL; RAT; TUMOR BIOPSY; TUMOR CELL; TUMOR GROWTH; TUMOR INVASION; TUMOR XENOGRAFT; WILD TYPE; BRAIN TUMOR; CULTURE TECHNIQUE; DRUG EFFECT; DRUG SCREENING; GENETICS; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PROTO ONCOGENE; TRANSCRIPTION INITIATION; TUMOR CELL LINE;

ANTIBODIES, MONOCLONAL, HUMANIZED; ANTINEOPLASTIC AGENTS; BRAIN NEOPLASMS; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; GENE AMPLIFICATION; GENES, ERBB-1; GLIOBLASTOMA; HUMANS; NEOPLASM INVASIVENESS; NEOVASCULARIZATION, PATHOLOGIC; RECEPTOR, EPIDERMAL GROWTH FACTOR; TRANSCRIPTIONAL ACTIVATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84886649252     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-013-1101-1     Document Type: Article

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