Effects of prothrombin fragments on thrombin, on thrombin formation, and separation from Ac-globulin (factor V)

Thrombosis Research

Volumn 8, Issue 1, 1976, Pages 83-97

  Seegers, Walter H ^a   Novoa, Eduardo ^a   Walz, Daniel A ^a   Andary, Thomas J ^a   Hassouna, Houria I ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 5; PROTHROMBIN; THROMBIN;

IN VITRO STUDY;

EID: 84886617528     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/0049-3848(76)90126-2     Document Type: Article

References (46)

1. Esterase and clotting activity derived from purified prothrombin
2. Further Studies of prothrombin derivatives
3. Mechanism of cyclic adenosine 3′, 5′-monophosphate regulation of platelet membrane phosphorylation-dephosphorylation, Ca binding and aggregation
4. Activation of human prothrombin by a procoagulant fraction from the venom of Echis carinatus
5. Prothrombin and thrombin: Selected aspects of thrombin formation, properties, inhibition, and immunology
6. Comments on Ac-globulin (Factor V): A source of personal rewards
7. Isolation and some properties of thrombin-E and other prothrombin derivatives
8. Purification and biochemistry of thrombin
9. Preparation of bovine prothrombin complex and purified prothrombin
10. Purification of bovine plasma Ac-globulin (Factor V)
11. Isolation and some properties of prethrombin and autoprothrombin III
12. Activation of purified prothrombin in ammonium sulfate solutions: Purification of autoprothrombin C
13. Procedures for the quantitative determination of autoprothrombin C
14. Une micro-methode de l'immuno-electrophorèse
15. Factors which influence the activity of purified thrombin
16. Two-stage procedure for the quantitative determination of prothrombin concentration
17. The conversion of prethrombin to thrombin
18. Prothrombin activation: Ac-globulin, lipid, platelet membrane, and autoprothrombin C (Factor Xa) requirements
19. A modified spectrophotometric determination of chymotrypsin trypsin and thrombin
20. Disc electrophoresis. I. Background and theory
21. Disc electrophoresis. II. Method and application to human serum proteins
22. The conversion of prothrombin to thrombin. II. Differentiation between thrombin- and Factor Xa-catalyzed proteolyses
23. Mechanism of bovine prothrombin activation by an insoluble preparation of bovine Factor Xa (thrombokinase)
24. Chemical characterization of fragments produced in the conversion of bovine prothrombin to thrombin by activated Factor X
25. The activation of prothrombin. II. Partial reactions, physical and chemical characterization of the intermediates of activation
26. Primary structure studies on thrombin and prothrombin
27. Note on the electrophoresis of thrombin
28. The primary structure of prothrombin, the role of vitamin K in blood coagulation and a thrombin-catalyzed ‘negative feed-back’ control mechanism for limiting the activation of prothrombin
29. The mode of action of vitamin K
30. Vitamin K-dependent modifications of glutamic acid residues in prothrombin
31. Primary structure of the vitamin K-dependent part of prothrombin
32. Some effects of calcium and strontium ions on three basic reactions of blood coagulation
33. The conversion of prothrombin to thrombin: The function of the propiece of prothrombin
34. Intermediates of prothrombin activation
35. The conversion of prothrombin to thrombin. V. The activation of prothrombin by Factor Xa in the presence of phospholipid
36. Ac-globulin (Factor V): Preparation of a practical product
37. Metabolic formation of a prothrombin derivative
38. Some effects of purified autoprothrombin C in blood clotting
39. Antithrombin: Inhibition of thrombin and autoprothrombin C (F-Xa) as a mutual depletion system
40. Formation of prethrombin-E, thrombin, and thrombin-E and their inhibition with antithrombin and enzyme inhibitors
41. Isolation of thrombin-E and the evolution of enzyme activity from prothrombin
42. The conversion of prothrombin to thrombin. IV. The function of the fragment 2 region during activation in the presence of Factor V
43. Prethrombin and the ultimate formation of thrombin
44. The conversion of prothrombin to thrombin. I. Characterization of the reaction products formed during the activation of bovine prothrombin