No association of the SLC1A2 rs3794087 allele with risk for essential tremor in the Spanish population

Pharmacogenetics and Genomics

Volumn 23, Issue 11, 2013, Pages 587-590

  García Martín, Elena ^a   Martínez, Carmen ^a   Alonso Navarro, Hortensia ^b,c   Benito León, Julián ^d,e   Lorenzo Betancor, Oswaldo ^f,g   Pastor, Pau ^e,f,g   Ortega Cubero, Sara ^e,f,g   López Alburquerque, Tomás ^h   Agúndez, José A G ^a   Jiménez Jiménez, Félix J ^b,c  

^a UNIVERSITY OF EXTREMADURA   (Spain)

^b Section of Neurology   (Japan)

^c UNIVERSITY OF ALCALÁ   (Spain)

^d UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^e INSTITUTO DE SALUD CARLOS III   (Spain)

^f Center for Applied Medical Research   (Spain)

^g UNIVERSITY CLINIC OF NAVARRA   (Spain)

^h HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

Author keywords

Essential tremor; Genetics; Polymorphisms; Risk factors; SLC1A2 gene

Indexed keywords

ADULT; AGED; ALLELE; ARTICLE; CONTROLLED STUDY; ESSENTIAL TREMOR; FAMILY HISTORY; FEMALE; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; ONSET AGE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RISK FACTOR; SEX; SOLUTE CARRIER FAMILY 1 GLIAL AFFINITY GLUTAMATE TRANSPORTER MEMBER 2 GENE;

ADULT; AGE OF ONSET; AGED; ALLELES; CASE-CONTROL STUDIES; ESSENTIAL TREMOR; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; GLUTAMATE PLASMA MEMBRANE TRANSPORT PROTEINS; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SPAIN;

EID: 84886599936     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0b013e328364db9d     Document Type: Article

References (19)

1. Jiménez-Jiménez FJ, Alonso-Navarro H, García- Martín E, Lorenzo-Betancor O, Pastor P, Agúndez JAG. Update on genetics of essential tremor. Acta Neurol Scand 2013. doi:10.1111/ane.12148. [Epub ahead of print].
2. Merner ND, Girard SL, Catoire H, Bourassa CV, Belzil VV, Riviè re JB, et al. Exome sequencing identifies FUS mutations as a cause of essential tremor. Am J Hum Genet 2012; 91: 313-319.
3. Parmalee N, Mirzozoda K, Kisselev S, Merner N, Dion P, Rouleau G, et al. Genetic analysis of the FUS/TLS gene in essential tremor. Eur J Neurol 2013; 20: 534-539.
4. Zheng W, Deng X, Liang H, Song Z, Gao K, Yang Y, Deng H. Genetic analysis of the fused in sarcoma gene in Chinese Han patients with essential tremor. Neurobiol Aging 2013; 34:e3-e4.
5. Labbé C, Soto-Ortolaza AI, Rayaprolu S, Harriott AM, Strongosky AJ, Uitti RJ, et al. Investigating the role of FUS exonic variants in essential tremor. Parkinsonism Relat Disord 2013; 19: 755-757.
6. Hedera P, Davis TL, Phibbs FT, Charles PD, Ledoux MS. FUS in familial essential tremor - the search for common causes is still on. Parkinsonism Relat Disord 2013. doi:pii: S1353-8020(13)00154-5. 10.1016/j. parkreldis.2013.04.009. [Epub ahead of print].
7. Ortega-Cubero S, Lorenzo-Betancor O, Lorenzo E, Alonso E, Coria F, Pastor MA, et al. Fused in sarcoma (FUS) gene mutations are not a frequent cause of essential tremor in Europeans. Neurobiol Aging 2013; 34: 2441.e9-2441.e11. [Epub ahead of print].
8. Kim K, Lee SG, Kegelman TP, Su ZZ, Das SK, Dash R, et al. Role of excitatory amino acid transporter-2 (EAAT2) and glutamate in neurodegeneration: opportunities for developing novel therapeutics. J Cell Physiol 2011; 226: 2484-2493.
9. De Felice B, Guida M, Guida M, Coppola C, De Mieri G, Cotrufo R. A miRNA signature in leukocytes from sporadic amyotrophic lateral sclerosis. Gene 2012; 508: 35-40.
10. Thier S, Lorenz D, Nothnagel M, Poremba C, Papengut F, Appenzeller S, et al. Polymorphisms in the glial glutamate transporter SLC1A2 are associated with essential tremor. Neurology 2012; 79: 243-248.
11. Tan EK, Foo JN, Tan L, Au WL, Prakash KM, Ng E, et al. SLC1A2 variant associated with essential tremor but not Parkinson disease in Chinese subjects. Neurology 2013; 80: 1618-1619.
12. Deuschl G, Bain P, Brin M. Consensus statement of the Movement Disorder Society on Tremor. Ad Hoc Scientific Committee. Mov Disord 1998; 13 (Suppl 3): 2-23.
13. Benito-Leó n J, Bemejo-Pareja F, Morales JM, Vega S, Molina JA. Prevalence of essential tremor in three elderly populations of Central Spain. Mov Disord 2003; 18: 389-394.
14. Stefansson H, Steinberg S, Petursson H, Gustafsson O, Gudjonsdottir IH, Jonsdottir GA, et al. Variant in the sequence of the LINGO1 gene confers risk of essential tremor. Nat Genet 2009; 41: 277-279.
15. Jimé nez-Jiménez FJ, García-Martín E, Lorenzo-Betancor O, Pastor P, Alonso- Navarro H, Agúndez JAG. LINGO1 and risk for essential tremor: results of a meta-analysis of rs9652490 and rs11856808. J Neurol Sci 2012; 317: 52-57.
16. Mally J, Baranyi M, Vizi ES. Change in the concentrations of amino acids in CSF and serum of patients with essential tremor. J Neural Transm 1996; 103: 555-560.
17. Manto M, Laute MA. A possible mechanism for the beneficial effect of ethanol in essential tremor. Eur J Neurol 2008; 15: 697-705.
18. Paterson NE, Malekiani SA, Foreman MM, Olivier B, Hanania T. Pharmacological characterization of harmaline-induced tremor activity in mice. Eur J Pharmacol 2009; 616: 73-80.
19. Rahimi Shourmasti F, Goudarzi I, Lashkarbolouki T, Abrari K, Elahdadi Salmani M, Goudarzi A. Effects of riluzole on harmaline induced tremor and ataxia in rats: biochemical, histological and behavioral studies. Eur J Pharmacol 2012; 695: 40-47.