Does EU legislation allow the use of the Benchmark dose (BMD) approach for risk assessment?

Regulatory Toxicology and Pharmacology

Volumn 67, Issue 2, 2013, Pages 182-188

  Brandon, E F A ^a   Bulder, A S ^a   van Engelen, J G M ^a   Mahieu, C M ^a   Mennes, W C ^a   Pronk, M E J ^a   Rietveld, A G ^a   van de Ven, B M ^a   ten Voorde, S E C G ^a   Wolterink, G ^a   Slob, W ^a   Zeilmaker, M J ^a   Bessems, J G M ^a  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

BMD; EU; Guidance; NOAEL; Regulation

Indexed keywords

BIOCIDE; COSMETIC; DRINKING WATER; FOOD ADDITIVE; PESTICIDE;

ANALYTICAL PARAMETERS; ARTICLE; BENCHMARK DOSE; BENCHMARK RESPONSE; CONSUMER ADVOCACY; EFFECT SIZE; ENVIRONMENTAL EXPOSURE; EUROPEAN UNION; FOOD CONTAMINATION; FOOD SAFETY; HAZARD ASSESSMENT; HUMAN; LAW; LC 50; LD 50; LOWEST OBSERVED ADVERSE EFFECT LEVEL; NO OBSERVED ADVERSE EFFECT LEVEL; PRACTICE GUIDELINE; PRIORITY JOURNAL; QUALITY CONTROL; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; RISK ASSESSMENT; VETERINARY MEDICINE;

ACCEPTABLE DAILY INTAKE; ACCEPTABLE OPERATOR EXPOSURE LEVEL; ACUTE REFERENCE DOSE; ADI; ADVERSE EFFECT LEVEL; AEL; AOEL; ARFD; BENCHMARK DOSE; BENCHMARK DOSE LOWER CONFIDENCE BOUND; BMD; BMDL; DERIVED NO EFFECT LEVEL; DG SANCO; DNEL; EFSA; EFSA CONTAM; EFSA SCIENTIFIC PANEL ON CONTAMINANTS IN THE FOOD CHAIN; EU; EU DIRECTORATE GENERAL FOR HEALTH AND CONSUMER AFFAIRS; EU SCIENTIFIC COMMITTEE ON CONSUMER SAFETY; EUROPEAN FOOD SAFETY AUTHORITY; GUIDANCE; INTERNATIONAL PROGRAMME ON CHEMICAL SAFETY; IPCS; JECFA; JOINT FAO/WHO EXPERT COMMITTEE ON FOOD ADDITIVES; LO(A)EL; LOWEST-OBSERVED-(ADVERSE)-EFFECT LEVEL; MAXIMUM RESIDUE LEVEL; MRL; NO(A)EL; NO-OBSERVED-(ADVERSE)-EFFECT LEVEL; NOAEL; POD; POINT OF DEPARTURE; REGULATION; SCCS;

ANIMALS; COSMETICS; DISINFECTANTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EUROPEAN UNION; FOOD ADDITIVES; GOVERNMENT REGULATION; NO-OBSERVED-ADVERSE-EFFECT LEVEL; PESTICIDES; RISK ASSESSMENT; VETERINARY DRUGS;

EID: 84886596623     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2013.07.005     Document Type: Article

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