BMP4 is increased in the aortas of diabetic ApoE knockout mice and enhances uptake of oxidized low density lipoprotein into peritoneal macrophages

Journal of Inflammation (United Kingdom)

Volumn 10, Issue 1, 2013, Pages

  Koga, Mitsuhisa ^a   Yamauchi, Atsushi ^a   Kanaoka, Yuki ^a   Jige, Ryusuke ^a   Tsukamoto, Anna ^a   Teshima, Nao ^a   Nishioku, Tsuyoshi ^a   Kataoka, Yasufumi ^a  

^a FUKUOKA UNIVERSITY   (Japan)

Author keywords

Atherosclerosis; BMP4; Diabetes; Macrophage; Oxidized low density lipoproteins

Indexed keywords

APOLIPOPROTEIN E; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 4; OXIDIZED LOW DENSITY LIPOPROTEIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; STREPTOZOCIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; AORTA; ARTICLE; CONTROLLED STUDY; IMMUNOFLUORESCENCE; IN VITRO STUDY; LIPID DIET; LIPOPROTEIN BLOOD LEVEL; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PROTEIN EXPRESSION; STREPTOZOCIN DIABETES; UPREGULATION; WESTERN BLOTTING; WILD TYPE;

EID: 84886530065     PISSN: None     EISSN: 14769255     Source Type: Journal    
DOI: 10.1186/1476-9255-10-32     Document Type: Article

References (35)

1. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. Haffner SM, Lehto S, Ronnemaa T, Pyorala K, Laakso M, N Engl J Med 1998 339 229 234 10.1056/NEJM199807233390404 9673301 (Pubitemid 28350165)
2. Oxidized LDL, LOX-1 and atherosclerosis. Mitra S, Goyal T, Mehta JL, Cardiovasc Drugs Ther 2011 25 419 429 10.1007/s10557-011-6341-5 21947818
3. Macrophages and oxidized low density lipoproteins in the pathogenesis of atherosclerosis. Yla-Herttuala S, Ann Med 1991 23 561 567 10.3109/ 07853899109150518 1721825
4. The role of oxidized low density lipoprotein in atherogenesis. Jialal I, Devaraj S, J Nutr 1996 126 1053S 1057S 8642431 (Pubitemid 26105633)
5. Oxidized low density lipoprotein induces differentiation and adhesion of human monocytes and the monocytic cell line U937. Frostegard J, Nilsson J, Haegerstrand A, Hamsten A, Wigzell H, Gidlund M, Proc Natl Acad Sci U S A 1990 87 904 908 10.1073/pnas.87.3.904 2300583
6. Induction of T-cell activation by oxidized low density lipoprotein. Frostegard J, Wu R, Giscombe R, Holm G, Lefvert AK, Nilsson J, Arterioscler Thromb 1992 12 461 467 10.1161/01.ATV.12.4.461 1558837
7. Bone morphogenetic proteins. Chen D, Zhao M, Mundy GR, Growth Factors 2004 22 233 241 10.1080/08977190412331279890 15621726 (Pubitemid 40136452)
8. Controlling TGF-beta signaling. Massague J, Chen YG, Genes Dev 2000 14 627 644 10733523
9. Bone morphogenetic proteins and their receptors: potential functions in the brain. Ebendal T, Bengtsson H, Soderstrom S, J Neurosci Res 1998 51 139 146 10.1002/(SICI)1097-4547(19980115)51:2<139::AID-JNR2>3.0.CO;2-E 9469567 (Pubitemid 28073021)
10. Embryonic patterning: to BMP or not to BMP, that is the question. Graff JM, Cell 1997 89 171 174 10.1016/S0092-8674(00)80196-8 9108472 (Pubitemid 27199889)
11. Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Hogan BL, Genes Dev 1996 10 1580 1594 10.1101/gad.10.13.1580 8682290 (Pubitemid 26268864)
12. Bone morphogenetic protein 4 mediates apoptosis of capillary endothelial cells during rat pupillary membrane regression. Kiyono M, Shibuya M, Mol Cell Biol 2003 23 4627 4636 10.1128/MCB.23.13.4627-4636.2003 12808102 (Pubitemid 36734751)
13. Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair. Wozney JM, Rosen V, Clin Orthop Relat Res 1998 346 26 37 9577407 (Pubitemid 28046864)
14. Inhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis. Derwall M, Malhotra R, Lai CS, Beppu Y, Aikawa E, Seehra JS, Zapol WM, Bloch KD, Yu PB, Arterioscler Thromb Vasc Biol 2012 32 613 622 10.1161/ATVBAHA.111.242594 22223731
15. Reactive oxygen species-selective regulation of aortic inflammatory gene expression in Type 2 diabetes. San Martin A, Du P, Dikalova A, Lassegue B, Aleman M, Gongora MC, Brown K, Joseph G, Harrison DG, Taylor WR, et al. Am J Physiol Heart Circ Physiol 2007 292 2073 H2082 10.1152/ajpheart.00943.2006 17237245 (Pubitemid 47084581)
16. Molecular mechanisms of vascular calcification: lessons learned from the aorta. Shao JS, Cai J, Towler DA, Arterioscler Thromb Vasc Biol 2006 26 1423 1430 10.1161/01.ATV.0000220441.42041.20 16601233 (Pubitemid 44288965)
17. Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress stimulates an inflammatory response. Sorescu GP, Sykes M, Weiss D, Platt MO, Saha A, Hwang J, Boyd N, Boo YC, Vega JD, Taylor WR, Jo H, J Biol Chem 2003 278 31128 31135 10.1074/jbc.M300703200 12766166 (Pubitemid 36994628)
18. Differential expression of bone matrix regulatory proteins in human atherosclerotic plaques. Dhore CR, Cleutjens JP, Lutgens E, Cleutjens KB, Geusens PP, Kitslaar PJ, Tordoir JH, Spronk HM, Vermeer C, Daemen MJ, Arterioscler Thromb Vasc Biol 2001 21 1998 2003 10.1161/hq1201.100229 11742876 (Pubitemid 34219753)
19. Thrombin and NAD(P)H oxidase-mediated regulation of CD44 and BMP4-Id pathway in VSMC, restenosis, and atherosclerosis. Vendrov AE, Madamanchi NR, Hakim ZS, Rojas M, Runge MS, Circ Res 2006 98 1254 1263 10.1161/01.RES. 0000221214.37803.79 16601225 (Pubitemid 43948080)
20. Bone morphogenic protein-4 induces hypertension in mice: role of noggin, vascular NADPH oxidases, and impaired vasorelaxation. Miriyala S, Gongora Nieto MC, Mingone C, Smith D, Dikalov S, Harrison DG, Jo H, Circulation 2006 113 2818 2825 10.1161/CIRCULATIONAHA.106.611822 16769910 (Pubitemid 44305294)
21. Bone morphogenic protein antagonists are coexpressed with bone morphogenic protein 4 in endothelial cells exposed to unstable flow in vitro in mouse aortas and in human coronary arteries: role of bone morphogenic protein antagonists in inflammation and atherosclerosis. Chang K, Weiss D, Suo J, Vega JD, Giddens D, Taylor WR, Jo H, Circulation 2007 116 1258 1266 10.1161/CIRCULATIONAHA.106.683227 17785623 (Pubitemid 47517537)
22. Endothelial dysfunction in the streptozotocin-induced diabetic apoE-deficient mouse. Ding H, Hashem M, Wiehler WB, Lau W, Martin J, Reid J, Triggle C, Br J Pharmacol 2005 146 1110 1118 16231005 (Pubitemid 41785322)
23. Decreased lipoprotein clearance is responsible for increased cholesterol in LDL receptor knockout mice with streptozotocin-induced diabetes. Goldberg IJ, Hu Y, Noh HL, Wei J, Huggins LA, Rackmill MG, Hamai H, Reid BN, Blaner WS, Huang LS, Diabetes 2008 57 1674 1682 10.2337/db08-0083 18346984
24. Inhibition of progression and stabilization of plaques by postnatal interferon-gamma function blocking in ApoE-knockout mice. Koga M, Kai H, Yasukawa H, Yamamoto T, Kawai Y, Kato S, Kusaba K, Kai M, Egashira K, Kataoka Y, Imaizumi T, Circ Res 2007 101 348 356 10.1161/CIRCRESAHA.106.147256 17495225 (Pubitemid 47267703)
25. Postnatal blocking of interferon-gamma function prevented atherosclerotic plaque formation in apolipoprotein E-knockout mice. Koga M, Kai H, Yasukawa H, Kato S, Yamamoto T, Kawai Y, Kusaba K, Seki Y, Kai M, Egashira K, et al. Hypertens Res 2007 30 259 267 10.1291/hypres.30.259 17510508 (Pubitemid 46605451)
26. Thioglycollate-elicited mouse peritoneal macrophages are less efficient than resident macrophages in antibody-dependent cell-mediated cytolysis. Shaw DR, Griffin FM Jr, J Immunol 1982 128 433 440 7054283 (Pubitemid 12207480)
27. Diabetes mellitus and atherosclerosis. Slavina ES, Madanat A, Pankov Yu A, Syrkin AL, Tertov VV, Orekhov AN, N Engl J Med 1987 317 836 (Pubitemid 17133364)
28. Inflammation, atherosclerosis, and coronary artery disease. Hansson GK, N Engl J Med 2005 352 1685 1695 10.1056/NEJMra043430 15843671 (Pubitemid 40530235)
29. The immunology of stroke: from mechanisms to translation. Iadecola C, Anrather J, Nat Med 2011 17 796 808 10.1038/nm.2399 21738161
30. Atherosclerosis is an inflammatory disease. Ross R, Am Heart J 1999 138 419 S420 10.1016/S0002-8703(99)70266-8 10539839
31. Atherosclerosis-an inflammatory disease. Ross R, N Engl J Med 1999 340 115 126 10.1056/NEJM199901143400207 9887164 (Pubitemid 29054847)
32. Inflammation in atherosclerosis. Libby P, Nature 2002 420 868 874 10.1038/nature01323 12490960 (Pubitemid 36019640)
33. Simvastatin attenuates plaque inflammation: evaluation by fluorodeoxyglucose positron emission tomography. Tahara N, Kai H, Ishibashi M, Nakaura H, Kaida H, Baba K, Hayabuchi N, Imaizumi T, J Am Coll Cardiol 2006 48 1825 1831 10.1016/j.jacc.2006.03.069 17084257 (Pubitemid 44648621)
34. Activation of vascular bone morphogenetic protein signaling in diabetes mellitus. Bostrom KI, Jumabay M, Matveyenko A, Nicholas SB, Yao Y, Circ Res 2011 108 446 457 10.1161/CIRCRESAHA.110.236596 21193740
35. High-density lipoproteins affect endothelial BMP-signaling by modulating expression of the activin-like kinase receptor 1 and 2. Yao Y, Shao ES, Jumabay M, Shahbazian A, Ji S, Bostrom KI, Arterioscler Thromb Vasc Biol 2008 28 2266 2274 10.1161/ATVBAHA.108.176958 18948634