A cytohistological study of p53 overexpression in ovarian neoplasms

South Asian Journal of Cancer

Volumn 1, Issue 2, 2012, Pages 59-62

  Choudhury, Monisha ^a   Goyal, Seema ^a   Pujani, Mukta ^a   Pujani, Meenu ^a  

^a LADY HARDINGE MEDICAL COLLEGE   (India)

Author keywords

Ovary; p53; Tumors

Indexed keywords

PROTEIN P53;

ARTICLE; BENIGN TUMOR; CANCER CYTODIAGNOSIS; CANCER GRADING; CANCER PROGNOSIS; CANCER STAGING; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; FEMALE; GENE MUTATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALIGNANT NEOPLASTIC DISEASE; OVARY TUMOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR SUPPRESSOR GENE;

EID: 84886508750     PISSN: 2278330X     EISSN: 22784306     Source Type: Journal    
DOI: 10.4103/2278-330X.103711     Document Type: Article

References (14)

1. Souka S, Kamel M, Rocca M, El-Assi M, Hebeishy N, Sheir SH. The combined use of cytological and frozen section in the intraoperative diagnosis of ovarian tumors. Int J GynecolObstet 1990;31:43-6.
2. Rosai J. Special techniques in surgical pathology. In: Rosai J, editor. Rosai and Ackerman's Surgical Pathology. 9th ed. St. Louis: Mosby; 2004. p. 37-92.
3. Klemi PJ, Pylkkanen L, Kiilholma P, Kurvinen K, Joensuu H. p53 protein detected by immunochemistry as a prognostic factor in patients with epithelial ovarian carcinoma. Cancer 1995;76:1201-8.
4. Nagai Y, Tanaka N, Horiuchi F, Ohki S, Seki K, Sekiya S. Diagnostic accuracy of intraoperative imprint cytology in ovarian epithelial tumors. Int J GynecolObstet 2001;72:159-64.
5. Inoue M, Fujita M, Enomoto T, Morimoto H, Monden T, Shimano T, et al. Immunohistochemical analysis of p53 in gynecologic tumors. Am J ClinPathol 1994;102:665-70.
6. Hartmann LC, Podratz KC, Keeney GL, Kamel NA, Edmonson JH, Grill JP, et al. Prognostic significance of p53 immunostaining in epithelial ovarian cancer. J ClinOncol 1994;12:64-9.
7. Marks JR, Davidoff AM, Kerns BJ, Humphrey PA, Pence JC, Dodge RK, et al. Overexpression and mutation of p53 in epithelial ovarian cancer. Cancer Res 1991;51:2979-84.
8. Bosari S, Viale G, Radaelli U, Bossi P, Bonoldi E, Coggi G. p53 accumulation in ovarian carcinomas and its prognostic implications. HumPathol 1993;24:1175-9.
9. Eltabbakh GH, Belinson JL, Kennedy AW, Biscotti CV, Casey G, Tubbs RR, et al. p53 overexpression is not an independent prognostic factor for patients with primary ovarian epithelial cancer. Cancer 1997;80:892-8.
10. Ozalp S, Yalcin OT, Minsin TH. Expression of p53 in epithelial ovarian cancer. Int J GynecolObstet 2000;71:277-8.
11. Kohler MF, Kerns BJ, Humphrey PA, Marks JR, Bast RCJr, Berchuck A. Mutation and overexpression of p53 in early stage epithelial ovarian cancer. ObstetGynecol 1993;81:643-50.
12. Min KW, Park MH. The expression of c-erbB-2, EGFR, p53 and Ki-67 in ovarian borderline tumors and carcinomas of the ovary. Korean J Pathol 2007;41:296-306.
13. Psyrri A, Kountourakis P, Yu Z, Papadimitriou C, Markakis S, Camp RL, et al. Analysis of p53 protein expression levels on ovarian cancer tissue microarray using automated quantitative analysis elucidates prognostic patient subsets. Ann Oncol 2010;18:709-15.
14. Anderson KS, Wong J, Vitonis A, Crum CP, Sluss PM, Labaer J, et al. p53 Autoantibodies as Potential Detection and Prognostic Biomarkers in Serous Ovarian Cancer. Cancer EpidemiolBiomarkers Prev 2010;19:859-68.