Oncogene- and oxidative stress-induced cellular senescence shows distinct expression patterns of proinflammatory cytokines in vascular endothelial cells

The Scientific World Journal

Volumn 2013, Issue , 2013, Pages

  Suzuki, Etsu ^a   Takahashi, Masao ^b   Oba, Shigeyoshi ^b   Nishimatsu, Hiroaki ^b  

^a ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; NERVE GROWTH FACTOR; NEUROTROPHIN; PROTEIN P21; PROTEIN P53; VASCULOTROPIN A; CYTOKINE; HYBRID PROTEIN;

ANGIOGENESIS; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CELL AGING; CYTOKINE PRODUCTION; DISEASE SEVERITY; DNA DAMAGE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; MAST CELL; ONCOGENE; OXIDATIVE STRESS; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SENESCENCE; VASCULAR ENDOTHELIAL CELL; BIOSYNTHESIS; COMPARATIVE STUDY; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; INFLAMMATION; METABOLISM; ONCOGENE RAS; PHYSIOLOGY; UMBILICAL VEIN ENDOTHELIAL CELL;

CELL AGING; CYTOKINES; GENE EXPRESSION REGULATION; GENES, RAS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYDROGEN PEROXIDE; INFLAMMATION; INTERLEUKIN-1BETA; NERVE GROWTH FACTOR; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS P21(RAS); RECOMBINANT FUSION PROTEINS;

EID: 84886488418     PISSN: None     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1155/2013/754735     Document Type: Article

References (22)

1. Hayflick L., The limited in vitro lifetime of human diploid cell strains. Experimental Cell Research 1965 37 3 614 636 2-s2.0-50549218525
2. Campisi J., Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 2005 120 4 513 522 2-s2.0-13944270339 10.1016/j.cell.2005.02.003 (Pubitemid 40269765)
3. Harley C. B., Futcher A. B., Greider C. W., Telomeres shorten during ageing of human fibroblasts. Nature 1990 345 6274 458 460 2-s2.0-0025279931 10.1038/345458a0 (Pubitemid 20178256)
4. Chen Q., Fischer A., Reagan J. D., Yan L.-J., Ames B. N., Oxidative DNA damage and senescence of human diploid fibroblast cells. Proceedings of the National Academy of Sciences of the United States of America 1995 92 10 4337 4341 2-s2.0-0029051426
5. Serrano M., Lin A. W., McCurrach M. E., Beach D., Lowe S. W., Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16(INK4a). Cell 1997 88 5 593 602 2-s2.0-0030944985 10.1016/S0092-8674(00) 81902-9 (Pubitemid 27152402)
6. Ben-Porath I., Weinberg R. A., The signals and pathways activating cellular senescence. International Journal of Biochemistry and Cell Biology 2005 37 5 961 976 2-s2.0-14644410453 10.1016/j.biocel.2004.10.013 (Pubitemid 40311739)
7. Dimri G. P., Lee X., Basile G., Acosta M., Scott G., Roskelley C., Medrano E. E., Linskens M., Rubelj I., Pereira-Smith O., Peacocke M., Campisi J., A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proceedings of the National Academy of Sciences of the United States of America 1995 92 20 9363 9367 2-s2.0-0029047362 10.1073/pnas.92.20.9363
8. Minamino T., Yoshida T., Tateno K., Miyauchi H., Zou Y., Toko H., Komuro I., Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis. Circulation 2003 108 18 2264 2269 2-s2.0-0242361641 10.1161/01.CIR.0000093274.82929.22 (Pubitemid 37363045)
9. Matthews C., Gorenne I., Scott S., Figg N., Kirkpatrick P., Ritchie A., Goddard M., Bennett M., Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: effects of telomerase and oxidative stress. Circulation Research 2006 99 2 156 164 2-s2.0-33747625689 10.1161/01.RES. 0000233315.38086.bc (Pubitemid 44297039)
10. Suzuki E., Nishimatsu H., Nagata D., Satonaka H., Goto A., Omata M., Fujita T., Nagai R., Hirata Y., Constitutive activation of proto-oncogen protein p21 induces cell cycle arrest in the G1 phase in contact-inhibited vascular endothelial cells. Hypertension Research 2002 25 5 773 778 2-s2.0-0036747150 (Pubitemid 35153767)
11. Suzuki E., Nagata D., Yoshizumi M., Kakoki M., Goto A., Omata M., Hirata Y., Reentry into the cell cycle of contact-inhibited vascular endothelial cells by a phosphatase inhibitor. Possible involvement of extracellular signal-regulated kinase and phosphatidylinositol 3-kinase. Journal of Biological Chemistry 2000 275 5 3637 3644 2-s2.0-0034602969 10.1074/jbc.275.5.3637 (Pubitemid 30083074)
12. Chien Y., Scuoppo C., Wang X., Fang X., Balgley B., Bolden J. E., Premsrirut P., Luo W., Chicas A., Lee C. S., Kogan S. C., Lowe S. W., Control of the senescence-associated secretory phenotype by NF- B promotes senescence and enhances chemosensitivity. Genes and Development 2011 25 20 2125 2136 2-s2.0-80054789761 10.1101/gad.17276711
13. Tilstra J. S., Robinson A. R., Wang J., Nf-kappab inhibition delays DNA damage-induced senescence and aging in mice. Journal of Clinical Investigation 2012 122 7 2601 2612
14. Coppé J.-P., Patil C. K., Rodier F., Sun Y., Muñoz D. P., Goldstein J., Nelson P. S., Desprez P.-Y., Campisi J., Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biology 2008 6 12 2853 2868 2-s2.0-58149163445 10.1371/journal.pbio.0060301
15. Acosta J. C., O'Loghlen A., Banito A., Guijarro M. V., Augert A., Raguz S., Fumagalli M., Da Costa M., Brown C., Popov N., Takatsu Y., Melamed J., d'Adda di Fagagna F., Bernard D., Hernando E., Gil J., Chemokine signaling via the CXCR2 receptor reinforces senescence. Cell 2008 133 6 1006 1018 2-s2.0-44649120132 10.1016/j.cell.2008.03.038 (Pubitemid 351795610)
16. Kuilman T., Michaloglou C., Vredeveld L. C. W., Douma S., van Doorn R., Desmet C. J., Aarden L. A., Mooi W. J., Peeper D. S., Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network. Cell 2008 133 6 1019 1031 2-s2.0-44649101304 10.1016/j.cell.2008.03.039 (Pubitemid 351787746)
17. Baumann H., Gauldie J., The acute phase response. Immunology Today 1994 15 2 74 80 2-s2.0-0028095919 10.1016/0167-5699(94)90137-6 (Pubitemid 24049800)
18. Kirii H., Niwa T., Yamada Y., Wada H., Saito K., Iwakura Y., Asano M., Moriwaki H., Seishima M., Lack of interleukin-1 β decreases the severity of atherosclerosis in apoE-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology 2003 23 4 656 660 2-s2.0-0037388984 10.1161/01.ATV.0000064374. 15232.C3 (Pubitemid 36438080)
19. Aloe L., Levi-Montalcini R., Mast cells increase in tissues of neonatal rats injected with the nerve growth factor. Brain Research 1977 133 2 358 366 2-s2.0-0017669366 10.1016/0006-8993(77)90772-7 (Pubitemid 8171234)
20. Lazarovici P., Marcinkiewicz C., Lelkes P. I., Cross talk between the cardiovascular and nervous systems: neurotrophic effects of vascular endothelial growth factor (VEGF) and angiogenic effects of nerve growth factor (NGF)-implications in drug development. Current Pharmaceutical Design 2006 12 21 2609 2622 2-s2.0-33745740520 10.2174/138161206777698738
21. Donovan M. J., Miranda R. C., Kraemer R., McCaffrey T. A., Tessarollo L., Mahadeo D., Sharif S., Kaplan D. R., Tsoulfas P., Parada L., Toran-Allerand C. D., Hajjar D. P., Hempstead B. L., Neurotrophin and neurotrophin receptors in vascular smooth muscle cells: regulation of expression in response to injury. American Journal of Pathology 1995 147 2 309 324 2-s2.0-0029085212
22. Kraemer R., Nguyen H., March K. L., Hempstead B., NGF activates similar intracellular signaling pathways in vascular smooth muscle cells as PDGF-BB but elicits different biological responses. Arteriosclerosis, Thrombosis, and Vascular Biology 1999 19 4 1041 1050 2-s2.0-0032921162 (Pubitemid 29177354)