Liquid chromatographic determination of CPZEN-45, a novel anti-tubercular drug, in biological samples

Journal of Pharmaceutical and Biomedical Analysis

Volumn 88, Issue , 2014, Pages 370-376

  Hanif, S N M ^a   Hickey, A J ^b   Garcia Contreras, L ^a  

^a UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^b RTI INTERNATIONAL   (United States)

Author keywords

CPZEN 45; Guinea pig; HPLC; Tuberculosis; Validation

Indexed keywords

ACETONITRILE; CAPRAZAMYCIN; CPZEN 45; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; BODY FLUID; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DISPOSITION; DRUG ISOLATION; DRUG TISSUE LEVEL; GUINEA PIG MODEL; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LUNG; LUNG LAVAGE; MALE; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHASE TRANSITION; PLASMA; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SPLEEN; TISSUES; ULTRAVIOLET SPECTROSCOPY;

CPZEN-45; GUINEA PIG; HPLC; TUBERCULOSIS; VALIDATION;

ANIMALS; ANTITUBERCULAR AGENTS; AZEPINES; BRONCHOALVEOLAR LAVAGE FLUID; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; GUINEA PIGS; INFUSIONS, INTRAVENOUS; INJECTIONS, SUBCUTANEOUS; LUNG; MALE; MYCOBACTERIUM TUBERCULOSIS; REPRODUCIBILITY OF RESULTS; SOFTWARE; SPLEEN; TISSUE DISTRIBUTION;

EID: 84886469710     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2013.09.014     Document Type: Article

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