메뉴 건너뛰기




Volumn 48, Issue 4, 2013, Pages 526-534

Accumulation of platelets in the liver may be an important contributory factor to thrombocytopenia and liver fibrosis in chronic hepatitis C

Author keywords

Hepatic stellate cells; PDGFR ; Platelet; Sinusoidal endothelial cells

Indexed keywords

PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; SMOOTH MUSCLE ACTIN;

EID: 84886457520     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-012-0656-2     Document Type: Article
Times cited : (46)

References (50)
  • 1
    • 0031014094 scopus 로고    scopus 로고
    • Platelets and inflammation: Role of platelet-derived growth factor, adhesion molecules and histamine
    • Mannaioni PF, Di Bello MG, Masini E. Platelets and inflammation: role of platelet-derived growth factor, adhesion molecules and histamine. Inflamm Res. 1997;46: 4-18.
    • (1997) Inflamm Res , vol.46 , pp. 4-18
    • Mannaioni, P.F.1    Di Bello, M.G.2    Masini, E.3
  • 4
    • 38949178835 scopus 로고    scopus 로고
    • Angiogenesis is regulated by a novel mechanism: Pro- and antiangiogenic proteins are organized into separate platelet a granules and differentially released
    • Italiano JE Jr, Richardson JL, Patel-Hett S, Battinelli E, Zaslavsky A, Short S, et al. Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet a granules and differentially released. Blood. 2008;111: 1227-33.
    • (2008) Blood , vol.111 , pp. 1227-1233
    • Italiano Jr., J.E.1    Richardson, J.L.2    Patel-Hett, S.3    Battinelli, E.4    Zaslavsky, A.5    Short, S.6
  • 5
    • 20444378130 scopus 로고    scopus 로고
    • Platelet-derived microparticles induce angiogenesis and stimulate post-ischemic revascularization
    • Brill A, Dashevsky O, Rivo J, Gozal Y, Varon D. Platelet-derived microparticles induce angiogenesis and stimulate post-ischemic revascularization. Cardiovasc Res. 2005;67: 30-8.
    • (2005) Cardiovasc Res , vol.67 , pp. 30-38
    • Brill, A.1    Dashevsky, O.2    Rivo, J.3    Gozal, Y.4    Varon, D.5
  • 7
    • 0035679001 scopus 로고    scopus 로고
    • Treatment of leg ulcers in b-thalassaemia intermedia: Use of platelet-derived wound healing factors from the patient's own platelets
    • Gilsanz F, Escalante F, Auray C, Olbes AG. Treatment of leg ulcers in b-thalassaemia intermedia: use of platelet-derived wound healing factors from the patient's own platelets. Br J Haematol. 2001;115:710.
    • (2001) Br J Haematol , vol.115 , pp. 710
    • Gilsanz, F.1    Escalante, F.2    Auray, C.3    Olbes, A.G.4
  • 8
    • 3042694375 scopus 로고    scopus 로고
    • The use of autologous platelet gel to treat difficult-to-heal wounds: A pilot study
    • Mazzucco L, Medici D, Serra M, Panizza R, Rivara G, Orecchia S, et al. The use of autologous platelet gel to treat difficult-to-heal wounds: a pilot study. Transfusion. 2004;44: 1013-8.
    • (2004) Transfusion , vol.44 , pp. 1013-1018
    • Mazzucco, L.1    Medici, D.2    Serra, M.3    Panizza, R.4    Rivara, G.5    Orecchia, S.6
  • 15
    • 0037220482 scopus 로고    scopus 로고
    • Liver fibrosis-from bench to bedside
    • Friedman SL. Liver fibrosis-from bench to bedside. J Hepatol. 2003;38(Suppl 1):S38-53.
    • (2003) J Hepatol , vol.38 , Issue.SUPPL. 1
    • Friedman, S.L.1
  • 17
    • 0027398194 scopus 로고
    • Mechanism of thrombocytopenia in liver cirrhosis: Kinetics of indium-111 tropolone labelled platelets
    • Aoki Y, Hirai K, Tanikawa K. Mechanism of thrombocytopenia in liver cirrhosis: kinetics of indium-111 tropolone labelled platelets. Eur J Nucl Med. 1993;20: 123-9.
    • (1993) Eur J Nucl Med , vol.20 , pp. 123-129
    • Aoki, Y.1    Hirai, K.2    Tanikawa, K.3
  • 18
    • 0022001132 scopus 로고
    • Kinetics and in vivo distribution of 111-In-labelled autologous platelets in chronic hepatic disease: Mechanisms of thrombocytopenia
    • Schmidt KG, Rasmussen JW, Bekker C, Madsen PE. Kinetics and in vivo distribution of 111-In-labelled autologous platelets in chronic hepatic disease: mechanisms of thrombocytopenia. Scand J Haematol. 1985;34: 39-46.
    • (1985) Scand J Haematol , vol.34 , pp. 39-46
    • Schmidt, K.G.1    Rasmussen, J.W.2    Bekker, C.3    Madsen, P.E.4
  • 19
    • 0018652845 scopus 로고
    • Splenic influences on the blood in chronic liver disease
    • Toghill PJ, Green S. Splenic influences on the blood in chronic liver disease. Q J Med. 1979;48: 613-25.
    • (1979) Q J Med , vol.48 , pp. 613-625
    • Toghill, P.J.1    Green, S.2
  • 20
    • 0013912854 scopus 로고
    • Pooling of platelets in the spleen: Role in the pathogenesis of "hypersplenic" thrombocytopenia
    • Aster RH. Pooling of platelets in the spleen: role in the pathogenesis of "hypersplenic" thrombocytopenia. J Clin Invest. 1966; 45: 645-57.
    • (1966) J Clin Invest , vol.45 , pp. 645-657
    • Aster, R.H.1
  • 22
    • 33845602180 scopus 로고    scopus 로고
    • Evaluation of platelet kinetics in patients with liver cirrhosis: Similarity to idiopathic thrombocytopenic purpura
    • Kajihara M, Okazaki Y, Kato S, Ishii H, Kawakami Y, Ikeda Y, et al. Evaluation of platelet kinetics in patients with liver cirrhosis: similarity to idiopathic thrombocytopenic purpura. J Gastroenterol Hepatol. 2007;22: 112-8.
    • (2007) J Gastroenterol Hepatol , vol.22 , pp. 112-118
    • Kajihara, M.1    Okazaki, Y.2    Kato, S.3    Ishii, H.4    Kawakami, Y.5    Ikeda, Y.6
  • 23
    • 0028892615 scopus 로고
    • Changes in platelet kinetics after a partial splenic arterial embolization in cirrhotic patients with hypersplenism
    • Noguchi H, Hirai K, Aoki Y, Sakata K, Tanikawa K. Changes in platelet kinetics after a partial splenic arterial embolization in cirrhotic patients with hypersplenism. Hepatology. 1995;22: 1682-8.
    • (1995) Hepatology , vol.22 , pp. 1682-1688
    • Noguchi, H.1    Hirai, K.2    Aoki, Y.3    Sakata, K.4    Tanikawa, K.5
  • 24
    • 0038659962 scopus 로고    scopus 로고
    • Scintigraphic prediction of therapeutic outcomes of splenectomy in patients with thrombocytopenia
    • Kinuya K, Matano S, Nakashima H, Taki S. Scintigraphic prediction of therapeutic outcomes of splenectomy in patients with thrombocytopenia. Ann Nucl Med. 2003;17: 161-4.
    • (2003) Ann Nucl Med , vol.17 , pp. 161-164
    • Kinuya, K.1    Matano, S.2    Nakashima, H.3    Taki, S.4
  • 25
    • 0030992275 scopus 로고    scopus 로고
    • Mechanism of thrombocytopenia induced by interferon therapy for chronic hepatitis B
    • Sata M, Yano Y, Yoshiyama Y, Ide T, Kumashiro R, Suzuki H, et al. Mechanism of thrombocytopenia induced by interferon therapy for chronic hepatitis B. J Gastroenterol. 1997;32: 206-10.
    • (1997) J Gastroenterol , vol.32 , pp. 206-210
    • Sata, M.1    Yano, Y.2    Yoshiyama, Y.3    Ide, T.4    Kumashiro, R.5    Suzuki, H.6
  • 27
    • 0028806153 scopus 로고
    • Chronic hepatitis. An update on terminology and reporting
    • Batts KP, Ludwig J. Chronic hepatitis. An update on terminology and reporting. Am J Surg Pathol. 1995;19: 1409-17.
    • (1995) Am J Surg Pathol , vol.19 , pp. 1409-1417
    • Batts, K.P.1    Ludwig, J.2
  • 28
    • 11444258295 scopus 로고    scopus 로고
    • Tumours of the liver and intrahepatic bile ducts. Hepatocellular carcinoma
    • Hamilton SR, Aaltonen LA, editors. World Health Organization Classification of Tumors. Lyon: IARC Press
    • Hirohashi S, Blum HE, Ishak KG, Deugnier Y, Kojiro M, Laurent Puig P, et al. Tumours of the liver and intrahepatic bile ducts. Hepatocellular carcinoma. In: Hamilton SR, Aaltonen LA, editors. Pathology and genetics of tumor of the digestive system. World Health Organization Classification of Tumors. Lyon: IARC Press; 2000. p. 159-72.
    • (2000) Pathology and Genetics of Tumor of the Digestive System , pp. 159-172
    • Hirohashi, S.1    Blum, H.E.2    Ishak, K.G.3    Deugnier, Y.4    Kojiro, M.5    Laurent Puig, P.6
  • 29
    • 0030091214 scopus 로고    scopus 로고
    • Expression of platelet-derived growth factor and its receptors in normal human liver and during active hepatic fibrogenesis
    • Pinzani M, Milani S, Herbst H, DeFranco R, Grappone C, Gentilini A, et al. Expression of platelet-derived growth factor and its receptors in normal human liver and during active hepatic fibrogenesis. Am J Pathol. 1996;148: 785-800.
    • (1996) Am J Pathol , vol.148 , pp. 785-800
    • Pinzani, M.1    Milani, S.2    Herbst, H.3    Defranco, R.4    Grappone, C.5    Gentilini, A.6
  • 30
    • 0025734994 scopus 로고
    • Perisinusoidal stellate cells of the liver: Important roles in retinol metabolism and fibrosis
    • Blomhoff R, Wake K. Perisinusoidal stellate cells of the liver: important roles in retinol metabolism and fibrosis. FASEB J. 1991;5: 271-7.
    • (1991) FASEB J , vol.5 , pp. 271-277
    • Blomhoff, R.1    Wake, K.2
  • 31
    • 0030863065 scopus 로고    scopus 로고
    • Expression of platelet-derived growth factor and its receptor in livers of patients with chronic liver disease
    • Ikura Y, Morimoto H, Ogami M, Jomura H, Ikeoka N, Sakurai M. Expression of platelet-derived growth factor and its receptor in livers of patients with chronic liver disease. J Gastroenterol. 1997;32: 496-501.
    • (1997) J Gastroenterol , vol.32 , pp. 496-501
    • Ikura, Y.1    Morimoto, H.2    Ogami, M.3    Jomura, H.4    Ikeoka, N.5    Sakurai, M.6
  • 32
    • 0022974205 scopus 로고
    • Organ distribution and fate of human platelets: Studies of asplenic and splenomegalic patients
    • Hill-Zobel RL, McCandless B, Kang SA, Chikkappa G, Tsan MF. Organ distribution and fate of human platelets: studies of asplenic and splenomegalic patients. Am J Hematol. 1986;23: 231-8.
    • (1986) Am J Hematol , vol.23 , pp. 231-238
    • Hill-Zobel, R.L.1    McCandless, B.2    Kang, S.A.3    Chikkappa, G.4    Tsan, M.F.5
  • 33
    • 50449098285 scopus 로고    scopus 로고
    • Mechanisms of thrombus formation
    • Furie B, Furie BC. Mechanisms of thrombus formation. N Engl J Med. 2008;359: 938-49.
    • (2008) N Engl J Med , vol.359 , pp. 938-949
    • Furie, B.1    Furie, B.C.2
  • 34
    • 0023724630 scopus 로고
    • Synthesis and release of platelet-activating factor by human vascular endothelial cells treated with tumor necrosis factor or interleukin 1a
    • Bussolino F, Camussi G, Baglioni C. Synthesis and release of platelet-activating factor by human vascular endothelial cells treated with tumor necrosis factor or interleukin 1a. J Biol Chem. 1988;263: 11856-61.
    • (1988) J Biol Chem , vol.263 , pp. 11856-11861
    • Bussolino, F.1    Camussi, G.2    Baglioni, C.3
  • 35
    • 0031937861 scopus 로고    scopus 로고
    • Involvement of intrasinusoidal hemostasis in the development of concanavalin A-induced hepatic injury in mice
    • Miyazawa Y, Tsutsui H, Mizuhara H, Fujiwara H, Kaneda K. Involvement of intrasinusoidal hemostasis in the development of concanavalin A-induced hepatic injury in mice. Hepatology. 1998;27: 497-506.
    • (1998) Hepatology , vol.27 , pp. 497-506
    • Miyazawa, Y.1    Tsutsui, H.2    Mizuhara, H.3    Fujiwara, H.4    Kaneda, K.5
  • 36
    • 14944375587 scopus 로고    scopus 로고
    • Immunology of hepatitis B virus and hepatitis C virus infection
    • Rehermann B, Nascimbeni M. Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol. 2005;5: 215-29.
    • (2005) Nat Rev Immunol , vol.5 , pp. 215-229
    • Rehermann, B.1    Nascimbeni, M.2
  • 37
    • 33846985915 scopus 로고    scopus 로고
    • Immunopathogenesis in hepatitis C virus cirrhosis
    • Spengler U, Nattermann J. Immunopathogenesis in hepatitis C virus cirrhosis. Clin Sci. 2007;112: 141-55.
    • (2007) Clin Sci , vol.112 , pp. 141-155
    • Spengler, U.1    Nattermann, J.2
  • 38
    • 35649007401 scopus 로고    scopus 로고
    • Viral and host factors induce macrophage activation and loss of toll-like receptor tolerance in chronic HCV infection
    • Dolganiuc A, Norkina O, Kodys K, Catalano D, Bakis G, Marshall C, et al. Viral and host factors induce macrophage activation and loss of toll-like receptor tolerance in chronic HCV infection. Gastroenterology. 2007;133: 1627-36.
    • (2007) Gastroenterology , vol.133 , pp. 1627-1636
    • Dolganiuc, A.1    Norkina, O.2    Kodys, K.3    Catalano, D.4    Bakis, G.5    Marshall, C.6
  • 39
    • 0029366299 scopus 로고
    • Platelet participation in liver injury from Gram-negative bacterial lipopolysaccharide in the rat
    • Pearson JM, Schultze AE, Jean PA, Roth RA. Platelet participation in liver injury from Gram-negative bacterial lipopolysaccharide in the rat. Shock. 1995;4: 178-86.
    • (1995) Shock , vol.4 , pp. 178-186
    • Pearson, J.M.1    Schultze, A.E.2    Jean, P.A.3    Roth, R.A.4
  • 40
    • 0009673797 scopus 로고    scopus 로고
    • Platelet accumulation induced by bacterial endotoxin in rats
    • Itoh H, Cicala C, Douglas GJ, Page CP. Platelet accumulation induced by bacterial endotoxin in rats. Thromb Res. 1996; 83: 405-19.
    • (1996) Thromb Res , vol.83 , pp. 405-419
    • Itoh, H.1    Cicala, C.2    Douglas, G.J.3    Page, C.P.4
  • 41
    • 0032101808 scopus 로고    scopus 로고
    • Translocation of platelets into Disse spaces and their entry into hepatocytes in response to lipopolysaccharides, interleukin-1 and tumour necrosis factor: The role of Kupffer cells
    • Nakamura M, Shibazaki M, Nitta Y, Endo Y. Translocation of platelets into Disse spaces and their entry into hepatocytes in response to lipopolysaccharides, interleukin-1 and tumour necrosis factor: the role of Kupffer cells. J Hepatol. 1998;28: 991-9.
    • (1998) J Hepatol , vol.28 , pp. 991-999
    • Nakamura, M.1    Shibazaki, M.2    Nitta, Y.3    Endo, Y.4
  • 42
    • 0024840085 scopus 로고
    • Effects of platelet-derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cells
    • Pinzani M, Gesualdo L, Sabbah GM, Abboud HE. Effects of platelet-derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cells. J Clin Invest. 1989;84: 1786-93.
    • (1989) J Clin Invest , vol.84 , pp. 1786-1793
    • Pinzani, M.1    Gesualdo, L.2    Sabbah, G.M.3    Abboud, H.E.4
  • 43
    • 0029658160 scopus 로고    scopus 로고
    • Signals controlling the expression of PDGF
    • Dirks RP, Bloemers HP. Signals controlling the expression of PDGF. Mol Biol Rep. 1996;22: 1-24.
    • (1996) Mol Biol Rep , vol.22 , pp. 1-24
    • Dirks, R.P.1    Bloemers, H.P.2
  • 46
    • 42949163491 scopus 로고    scopus 로고
    • Mechanisms of hepatic fibrogenesis
    • Friedman SL. Mechanisms of hepatic fibrogenesis. Gastroenterology. 2008;134: 1655-69.
    • (2008) Gastroenterology , vol.134 , pp. 1655-1669
    • Friedman, S.L.1
  • 47
    • 79551482849 scopus 로고    scopus 로고
    • Liver specific overexpression of platelet-derived growth factor-B accelerates liver cancer development in chemically induced liver carcinogenesis
    • Maass T, Thieringer FR, Mann A, Longerich T, Schirmacher P, Strand D, et al. Liver specific overexpression of platelet-derived growth factor-B accelerates liver cancer development in chemically induced liver carcinogenesis. Int J Cancer. 2011;128: 1259-68.
    • (2011) Int J Cancer , vol.128 , pp. 1259-1268
    • Maass, T.1    Thieringer, F.R.2    Mann, A.3    Longerich, T.4    Schirmacher, P.5    Strand, D.6
  • 48
    • 0037380709 scopus 로고    scopus 로고
    • Novel PDGF family members: PDGF-C and PDGF-D
    • Li X, Eriksson U. Novel PDGF family members: PDGF-C and PDGF-D. Cytokine Growth Factor Rev. 2003;14: 91-8.
    • (2003) Cytokine Growth Factor Rev , vol.14 , pp. 91-98
    • Li, X.1    Eriksson, U.2
  • 49
    • 0025776396 scopus 로고
    • Platelet-derived growth factor (PDGF) stimulates PDGF receptor subunit dimerization and intersubunit trans-phosphorylation
    • Kelly JD, Haldeman BA, Grant FJ, Murray MJ, Seifert RA, Bowen-Pope DF, et al. Platelet-derived growth factor (PDGF) stimulates PDGF receptor subunit dimerization and intersubunit trans-phosphorylation. J Biol Chem. 1991;266: 8987-92.
    • (1991) J Biol Chem , vol.266 , pp. 8987-8992
    • Kelly, J.D.1    Haldeman, B.A.2    Grant, F.J.3    Murray, M.J.4    Seifert, R.A.5    Bowen-Pope, D.F.6
  • 50
    • 0029807253 scopus 로고    scopus 로고
    • Pathomorphological study of Kupffer cells in hepatocellular carcinoma and hyperplastic nodular lesions in the liver
    • Tanaka M, Nakashima O, Wada Y, Kage M, Kojiro M. Pathomorphological study of Kupffer cells in hepatocellular carcinoma and hyperplastic nodular lesions in the liver. Hepatology. 1996; 24: 807-12.
    • (1996) Hepatology , vol.24 , pp. 807-812
    • Tanaka, M.1    Nakashima, O.2    Wada, Y.3    Kage, M.4    Kojiro, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.