On identification of sinoatrial node in zebrafish heart based on functional time series from optical mapping

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

Volumn , Issue , 2013, Pages 6518-6521

  Ding, Weiguang ^a   Lin, Eric ^a   Ribeiro, Amanda ^a   Sarunic, Marinko V ^a   Tibbits, Glen F ^a   Beg, Mirza Faisal ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTION POTENTIAL PROPAGATION; CARDIAC DISEASE; CARDIOVASCULAR MODELS; DISCRETIZATIONS; EFFECTIVE APPROACHES; FUNCTIONAL TIME SERIES; MANUAL ANALYSIS; ZEBRAFISH HEARTS;

BIOELECTRIC POTENTIALS; MAPPING; PHYSIOLOGICAL MODELS; PHYSIOLOGY; TIME SERIES;

HEART;

FLUORESCENT DYE;

ACTION POTENTIAL; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; CLUSTER ANALYSIS; HEART; HEART DISEASE; HEART RATE; OPTICS; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL NOISE RATIO; SINUS NODE; TIME; ZEBRA FISH;

ACTION POTENTIALS; ANIMALS; CLUSTER ANALYSIS; FLUORESCENT DYES; HEART; HEART DISEASES; HEART RATE; MODELS, CARDIOVASCULAR; OPTICS AND PHOTONICS; SIGNAL-TO-NOISE RATIO; SINOATRIAL NODE; TIME FACTORS; ZEBRAFISH;

EID: 84886451540     PISSN: 1557170X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/EMBC.2013.6611048     Document Type: Conference Paper

References (13)

1. Jeroen Bakkers, "Zebrafish as a model to study cardiac development and human cardiac disease., " Cardiovascular research, vol. 91, no. 2, pp. 279-88, July 2011.
2. B.R. Choi and G. Salama, "Optical mapping of atrioventricular node reveals a conduction barrier between atrial and nodal cells, " American Journal of Physiology-Heart and Circulatory Physiology, vol. 274, no. 3, pp. H829-H845, 1998.
3. I.R. Efimov and T.N. Mazgalev, "High-resolution, three-dimensional fluorescent imaging reveals multilayer conduction pattern in the atrioventricular node, " Circulation, vol. 98, no. 1, pp. 54-57, 1998.
4. A.O. Verkerk, G.S.C. Geuzebroek, M.W. Veldkamp, and R. Wilders, "Effects of acetylcholine and noradrenalin on action potentials of isolated rabbit sinoatrial and atrial myocytes, " Frontiers in Physiology, vol. 3, 2012.
5. Federico Tessadori, Jan Hendrik van Weerd, Silja B Burkhard, Arie O Verkerk, Emma de Pater, Bastiaan J Boukens, Aryan Vink, Vincent M Christoffels, and Jeroen Bakkers, "Identification and functional characterization of cardiac pacemaker cells in zebrafish., " PloS one, vol. 7, no. 10, pp. e47644, 10 2012.
6. Jacob I Laughner, Fu Siong Ng, Matthew S Sulkin, R Martin Arthur, and Igor R Efimov, "Processing and analysis of cardiac optical mapping data obtained with potentiometric dyes., " American journal of physiology. Heart and circulatory physiology, vol. 303, no. 7, pp. H753-65, Oct. 2012.
7. Vadim V Fedorov, Alexey V Glukhov, Roger Chang, Geran Kostecki, Hyuliya Aferol, William J Hucker, Joseph P Wuskell, Leslie M Loew, Richard B Schuessler, Nader Moazami, et al., "Optical mapping of the isolated coronary-perfused human sinus node, " Journal of the American College of Cardiology, vol. 56, no. 17, pp. 1386-1394, 2010.
8. V.G. Fast and R.E. Ideker, "Simultaneous optical mapping of transmembrane potential and intracellular calcium in myocyte cultures, " Journal of cardiovascular electrophysiology, vol. 11, no. 5, pp. 547- 556, 2007.
9. C.J. Jou, K.W. Spitzer, and M. Tristani-Firouzi, "Blebbistatin effectively uncouples the excitation-contraction process in zebrafish embryonic heart, " Cellular Physiology and Biochemistry, vol. 25, no. 4-5, pp. 419-424, 2010.
10. E.M. Goldys, Fluorescence Applications in Biotechnology and Life Sciences, Wiley, 2009.
11. R. Xu and D. Wunsch, Clustering, IEEE Press Series on Computational Intelligence. Wiley, 2008.
12. DL Pham, "Spatial Models for Fuzzy Clustering, " Computer Vision and Image Understanding, vol. 84, no. 2, pp. 285-297, Nov. 2001.
13. P. Nemtsas, E.Wettwer, T. Christ, G.Weidinger, and U. Ravens, "Adult zebrafish heart as a model for human heart? an electrophysiological study, " Journal of molecular and cellular cardiology, vol. 48, no. 1, pp. 161-171, 2010.