Expression of cancer/testis (CT) antigens in squamous cell carcinoma of the head and neck: Evaluation as markers of squamous dysplasia

Pathology Research and Practice

Volumn 209, Issue 11, 2013, Pages 721-726

  Piotti, Kathryn C ^a   Scognamiglio, Theresa ^a   Chiu, Rita ^b   Chen, Yao Tseng ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b LUDWIG INSTITUTE FOR CANCER RESEARCH   (Australia)

Author keywords

Biomarkers; Immunohistochemistry; Tumor specific antigens

Indexed keywords

CANCER TESTIS ANTIGEN; CANCER TESTIS ANTIGEN 10; CANCER TESTIS ANTIGEN 7; MELANOMA ANTIGEN; NY ESO 1 ANTIGEN; PROTEIN CT45; PROTEIN GAGE; PROTEIN NXF2; PROTEIN SAGE1; UNCLASSIFIED DRUG;

ADULT; ANTIBODY DETECTION; ANTIGEN DETECTION; ANTIGEN EXPRESSION; ARTICLE; CELLULAR DISTRIBUTION; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE SEVERITY; DYSPLASIA; FEMALE; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; SQUAMOUS DYSPLASIA; SQUAMOUS PAPILLOMA WITH DYSPLASIA; TISSUE MICROARRAY; TUMOR DIFFERENTIATION; TUMOR LOCALIZATION; X CHROMOSOME;

BIOMARKERS; IMMUNOHISTOCHEMISTRY; TUMOR-SPECIFIC ANTIGENS;

ANTIGENS, NEOPLASM; BIOPSY; CARCINOMA, SQUAMOUS CELL; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NEOPLASM GRADING; TESTIS; TUMOR MARKERS, BIOLOGICAL;

EID: 84886430348     PISSN: 03440338     EISSN: 16180631     Source Type: Journal    
DOI: 10.1016/j.prp.2013.08.004     Document Type: Article

References (30)

1. Almeida L.G., Sakabe N.J., deOliveira A.R., Silva M.C., Mundstein A.S., Cohen T., Chen Y.T., Chua R., Gurung S., Gnjatic S., Jungbluth A.A., Caballero O.L., Bairoch A., Kiesler E., White S.L., Simpson A.J., Old L.J., Camargo A.A., Vasconcelos A.T. CTdatabase: a knowledge-base of high-throughput and curated data on cancer-testis antigens. Nucleic Acids Res. 2009, 37(Database issue):D816-D819. 10.1093/nar/gkn673.
2. Atanackovic D., Blum I., Cao Y., Wenzel S., Bartels K., Faltz C., Hossfeld D.K., Hegewisch-Becker S., Bokemeyer C., Leuwer R. Expression of cancer-testis antigens as possible targets for antigen-specific immunotherapy in head and neck squamous cell carcinoma. Cancer Biol. Ther. 2006, 5:1218-1225.
3. Boon T., Coulie P.G., Van den Eynde B. Tumor antigens recognized by T cells. Immunol. Today 1997, 18:267-268.
4. Caballero O.L., Chen Y.T. Cancer/testis (CT) antigens: potential targets for immunotherapy. Cancer Sci. 2009, 100:2014-2021.
5. Carneiro T.E., Marinho S.A., Verli F.D., Mesquita A.T., Lima N.L., Miranda J.L. Oral squamous papilloma: clinical, histologic and immunohistochemical analyses. J. Oral Sci. 2009, 51:367-372.
6. Chen Y.T., Chiu R., Lee P., Beneck D., Jin B., Old L.J. Chromosome X-encoded cancer/testis antigens show distinctive expression patterns in developing gonads and in testicular seminoma. Hum. Reprod. 2011, 10.1093/humrep/der330.
7. Chen Y.T., Gure A.O., Tsang S., Stockert E., Jager E., Knuth A., Old L.J. Identification of multiple cancer/testis antigens by allogeneic antibody screening of a melanoma cell line library. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:6919-6923.
8. Chen Y.T., Hsu M., Lee P., Shin S.J., Mhawech-Fauceglia P., Odunsi K., Altorki N.K., Song C.J., Jin B.Q., Simpson A.J., Old L.J. Cancer/testis antigen CT45: analysis of mRNA and protein expression in human cancer. Int. J. Cancer 2009, 124:2893-2898.
9. Chen Y.T., Ross D.S., Chiu R., Zhou X.K., Chen Y.Y., Lee P., Hoda S.A., Simpson A.J., Old L.J., Caballero O., Neville A.M. Multiple cancer/testis antigens are preferentially expressed in hormone-receptor negative and high-grade breast cancers. PLoS ONE 2011, 6:e17876. 10.1371/journal.pone.0017876.
10. Chen Y.T., Scanlan M.J., Sahin U., Tureci O., Gure A.O., Tsang S., Williamson B., Stockert E., Pfreundschuh M., Old L.J. A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening. Proc. Natl. Acad. Sci. U. S. A. 1997, 94:1914-1918.
11. Chen Y.T., Venditti C.A., Theiler G., Stevenson B.J., Iseli C., Gure A.O., Jongeneel C.V., Old L.J., Simpson A.J. Identification of CT46/HORMAD1, an immunogenic cancer/testis antigen encoding a putative meiosis-related protein. Cancer Immunol. 2005, 5:9.
12. Dyrskjot L., Zieger K., Kissow Lildal T., Reinert T., Gruselle O., Coche T., Borre M., Orntoft T.F. Expression of MAGE-A3, NY-ESO-1, LAGE-1 and PRAME in urothelial carcinoma. Br. J. Cancer 2012, 107:116-122.
13. Fleskens S.A., Bergshoeff V.E., Voogd A.C., van Velthuysen M.L., Bot F.J., Speel E.J., Kremer B., Takes R., Slootweg P. Interobserver variability of laryngeal mucosal premalignant lesions: a histopathological evaluation. Mod. Pathol. 2011, 24:892-898.
14. Figueiredo D.L., Mamede R.C., Proto-Siqueira R., Neder L., Silva W.A., Zago M.A. Expression of cancer testis antigens in head and neck squamous cell carcinomas. Head Neck 2006, 28:614-619.
15. Figueiredo D.L., Mamede R.C., Spagnoli G.C., Silva W.A., Zago M., Neder L., Jungbluth A.A., Saggioro F.P. High expression of cancer testis antigens MAGE-A, MAGE-C1/CT7, MAGE-C2/CT10, NY-ESO-1, and gage in advanced squamous cell carcinoma of the larynx. Head Neck 2011, 33:702-707.
16. Gallo O., Franchi A., Chiarelli I., Porfirio B., Grande A., Simonetti L., Bocciolini C., Fini-Storchi O. Potential biomarkers in predicting progression of epithelial hyperplastic lesions of the larynx. Acta Otolaryngol. Suppl. 1997, 527:30-38.
17. Gologan O., Barnes E.L., Hunt J.L. Potential diagnostic use of p16INK4A, a new marker that correlates with dysplasia in oral squamoproliferative lesions. Am. J. Surg. Pathol. 2005, 29:792-796.
18. Grigoriadis A., Caballero O.L., Hoek K.S., da Silva L., Chen Y.T., Shin S.J., Jungbluth A.A., Miller L.D., Clouston D., Cebon J., Old L.J., Lakhani S.R., Simpson A.J., Neville A.M. CT-X antigen expression in human breast cancer. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:13493-13498.
19. Gure A.O., Stockert E., Arden K.C., Boyer A.D., Viars C.S., Scanlan M.J., Old L.J., Chen Y.T. CT10: a new cancer-testis (CT) antigen homologous to CT7 and the MAGE family, identified by representational-difference analysis. Int. J. Cancer 2000, 85:726-732.
20. Kurashige T., Noguchi Y., Saika T., Ono T., Nagata Y., Jungbluth A., Ritter G., Chen Y.T., Stockert E., Tsushima T., Kumon H., Old L.J., Nakayama E. Ny-ESO-1 expression and immunogenicity associated with transitional cell carcinoma: correlation with tumor grade. Cancer Res. 2001, 61:4671-4674.
21. McLaren K.M., Burnett R.A., Goodlad J.R., Howatson S.R., Lang S., Lee F.D., Lessells A.M., Ogston S., Robertson A.J., Simpson J.G., Smith G.D., Tavadia H.B., Walker F. Consistency of histopathological reporting of laryngeal dysplasia. The Scottish Pathology Consistency Group. Histopathology 2000, 37:460-463.
22. Montoro J.R., Mamede R.C., Neder Serafini L., Saggioro F.P., Figueiredo D.L., Silva W.A., Jungbluth A.A., Spagnoli G.C., Zago M.A. Expression of cancer-testis antigens MAGE-A4 and MAGE-C1 in oral squamous cell carcinoma. Head Neck 2012, 34:1123-1128.
23. Munck-Wikland E., Kuylenstierna R., Lindholm J., Auer G. p53 immunostaining and image cytometry DNA analysis in precancerous and cancerous squamous epithelial lesions of the larynx. Head Neck 1997, 19:107-115.
24. Nankivell P., Weller M., McConkey C., Paleri V., Mehanna H. Biomarkers in laryngeal dysplasia: a systematic review. Head Neck 2011, 33:1170-1176.
25. Nishioka H., Hiasa Y., Hayashi I., Kitahori Y., Konishi N., Sugimura M. Immunohistochemical detection of p53 oncoprotein in human oral squamous cell carcinomas and leukoplakias: comparison with proliferating cell nuclear antigen staining and correlation with clinicopathological findings. Oncology 1993, 50:426-429.
26. Pignataro L., Capaccio P., Pruneri G., Carboni N., Buffa R., Neri A., Ottaviani A. The predictive value of p53, MDM-2, cyclin D1 and Ki67 in the progression from low-grade dysplasia towards carcinoma of the larynx. J. Laryngol. Otol. 1998, 112:455-459.
27. Rimoldi D., Salvi S., Schultz-Thater E., Spagnoli G.C., Cerottini J.C. Anti-MAGE-3 antibody 57B and anti-MAGE-1 antibody 6C1 can be used to study different proteins of the MAGE-A family. Int. J. Cancer 2000, 86:749-751.
28. Scanlan M.J., Gure A.O., Jungbluth A.A., Old L.J., Chen Y.T. Cancer/testis antigens: an expanding family of targets for cancer immunotherapy. Immunol. Rev. 2002, 188:22-32.
29. Simpson A.J., Caballero O.L., Jungbluth A., Chen Y.T., Old L.J. Cancer/testis antigens, gametogenesis and cancer. Nat. Rev. Cancer 2005, 5:615-625.
30. van der Bruggen P., Traversari C., Chomez P., Lurquin C., De Plaen E., Van den Eynde B., Knuth A., Boon T. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science 1991, 254:1643-1647.