A comparative randomized open label study to evaluate efficacy, safety and cost effectiveness between topical 2% sertaconazole and topical 1% butenafine in tinea infections of skin

Indian Journal of Dermatology

Volumn 58, Issue 6, 2013, Pages 451-456

  Thaker, Saket ^a   Mehta, Dimple ^a   Shah, Hiral ^a   Dave, Jayendra ^a   Mundhava, Shailesh ^a  

^a KEM HOSPITAL   (India)

Author keywords

Butenafine; cost effectiveness; efficacy; safety; sertaconazole; tinea infections

Indexed keywords

BUTENAFINE; CHLORPHENIRAMINE MALEATE; SERTACONAZOLE;

ABSENCE OF SIDE EFFECTS; ARTICLE; CLINICAL EVALUATION; COMPARATIVE STUDY; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DRUG EFFICACY; DRUG SAFETY; ERYTHEMA; FOLLOW UP; FUNGUS CULTURE; HUMAN; MAJOR CLINICAL STUDY; OPEN STUDY; PRURITUS; RANDOMIZED CONTROLLED TRIAL; RELAPSE; TINEA; TINEA CORPORIS; TINEA CRURIS; TREATMENT RESPONSE; TRICHOPHYTON MENTAGROPHYTES; TRICHOPHYTON RUBRUM; TRICHOPHYTON VERRUCOSUM;

EID: 84886415210     PISSN: 00195154     EISSN: 19983611     Source Type: Journal    
DOI: 10.4103/0019-5154.119955     Document Type: Article

References (18)

1. Sobera JO, Elewski BE. Fungal diseases. In: Sobera JO, Elewski BE, editors. Dermatology. 2nd ed. USA: Mosby Elsevier; 2008. p. 1135-63.
2. Tripahi KD. Antifungal drugs. In: Tripathi KD, editor. Essentials of Medical Pharmacology, 6th Ed. New Delhi: Jaypee Brothers; 2008. p. 757-66.
3. Brunton LS, Lazo JS, Parker KL. Antifungal Drugs. In: Brunton LS, Lazo JS, Parker KL, editor. Goodman and Gilman's the pharmacological basis of therapeutics, 11th ed. USA: McGraw-Hill Publication; 2008. p. 1225-42.
4. Carrillo-Munoz JA, Cristina T, Cárdenes DC, Estivill D, Giusiano G. Sertaconazole nitrate shows fungicidal and fungistatic activities against Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, causative agents of tinea pedis. Antimicrob Agents Chemother 2011;55:4420-1.
5. Croxtall JD, Plosker GL. Sertaconazole: A review of its use in the management of superficial mycoses in dermatology and gynecology. Drugs 2009;69:339-59.
6. Verma S, Heffernan MP. Superficial Fungal Infection: Dermatophytosis, Onychomycosis, Tinea nigra, Piedra. In Verma S, Heffernan MP, editors. Dermatology in General Medicine. 6th ed. Vol.2 USA: McGraw Hill Inc; 2003. p. 1989-2001.
7. McNeely W, Spencer CM. Butenafine. Drugs 1998;55:405-12.
8. Jerajani HR, Amladi ST Bongale R, Adepu V, Tendolkar UM, Sentamilselvi G, et al. Evaluation of clinical efficacy and safety of once daily topical administration of 1% oxiconazole cream and lotion in dermatophytosis: An open label, non comparative multicentre study. Indian J Dermatol Venereol Leprol 2000;66:188-92.
9. Heitjan DF, Moskowitz AJ, Whang W. Bayesian estimation of cost effectiveness ratios from clinical trials. Health Econ 1999;8:191-201.
10. Long CC, Finlay AY. The fingertip unit: A new practical measure. Cli Exp Dermatol 1991;16:444-7.
11. Chander J. Dermatophytosis. In Chander J, editor. Textbook of medical mycology, 3rded. New Delhi: Mehta Publishers; 2009. p. 122-46.
12. Sen SS, Rasul ES. Dermatophytosis in Assam. Indian J Med Microbiol 2006;24:77-8.
13. Kannan P, Janaki C, Selvi GS. Prevalence of dermatophytes and other fungal agents isolated from clinical samples. Indian J Med Microbiol 2006;24:212-5.
14. Sharma A, Saple DG, Surjushe A, Rao GR, Kura M, Ghosh S, et al. Efficacy and tolerability of sertaconazole nitrate 2% cream vs. miconazole in patients with cutaneous dermatophytosis. Mycoses 2011;54:217-22.
15. Alomar C, Bassas S, Casas M, Crespo V, Ferrándiz C, Fonseca E, et al. Multi-centre double-blind trial on the efficacy and safety of sertaconazole 2% cream in comparison with miconazole 2% cream on patients suffering From cutaneous mycoses. Arzneimittelforschung 1992;42:767-73.
16. Tschen E, Elewski B, Gorsulowsky DC, Pariser DM. Treatment of interdigital tinea pedis with a 4-week once daily regimen of butenafine hydrochloride 1% cream. J Am Acad Dermatol 1997;36:S9-14.
17. Ramam M, Prasad HR, Manchanda Y, Khaitan BK, Banerjee U, Mukhopadhyaya A, et al. Randomized controlled trial of topical butenafine in tinea cruris and tinea corporis. Indian J Dermatol Venereol Leprol 2003;69:154-8.
18. Lesher JL Jr, Babel DE, Stewart DM, Jones TM, Kaminester L, Goldman M, et al. Butenafine 1% cream in the treatment of tinea cruris: A multicentre, vehicle-controlled, double-blind trial. J Am Acad Dermatol 1997;36:S20-4.