A 2-hit model for chronic GVHD

Blood

Volumn 122, Issue 5, 2013, Pages 623-624

  Parkman, Robertson ^a,b  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; ANTIGEN;

CHRONIC DISEASE; CHRONIC GRAFT VERSUS HOST DISEASE; GRAFT RECIPIENT; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNE DYSREGULATION; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; T LYMPHOCYTE; THYMUS; ANIMAL; EPITHELIUM CELL; FEMALE; GENETICS; GRAFT VERSUS HOST REACTION; IMMUNOLOGY; METABOLISM; NOTE;

ANIMALS; ANTIGENS; EPITHELIAL CELLS; FEMALE; GRAFT VS HOST DISEASE; THYMUS GLAND;

EID: 84886404591     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-06-507376     Document Type: Short Survey

References (10)

1. Dertschnig S, Nusspaumer G, Ivanek R., Hauri-Hohl MM, Holländer GA, Krenger W. Epithelial cytoprotection sustains ectopic expression of tissue-restricted antigens in the thymus during murine acute GVHD. Blood. 2013; 122(5): 837-841.
2. Martin PJ, Inamoto Y, Carpenter P.A., Lee SJ, Flowers ME. Treatment of chronic graft-versus-host disease: Past, present and future. Korean J Hematol. 2011; 46(3): 153-163.
3. Blazar BR, Murphy WJ, Abedi M. Advances in graft-versus-host disease biology and therapy. Nat Rev Immunol. 2012; 12(6): 443-458.
4. Parkman R. Clonal analysis of murine graft-vs-host disease. I. Phenotypic and functional analysis of T lymphocyte clones. J Immunol. 1986; 136(10): 3543-3548. (Pubitemid 16122043)
5. Sakoda Y, Hashimoto D, Asakura S., et al. Donor-derived thymic-dependent T cells cause chronic graft-versus-host disease. Blood. 2007; 109(4): 1756-1764. (Pubitemid 46239612)
6. Zhang Y, Hexner E, Frank D., Emerson SG. CD4+ T cells generated de novo from donor hemopoietic stem cells mediate the evolution from acute to chronic graft-versus-host disease. J Immunol. 2007; 179(5): 3305-3314.
7. Koreth J, Matsuoka K, Kim H.T., et al. Interleukin-2 and regulatory T cells in graft-versus-host disease. N Engl J Med. 2011; 365(22): 2055-2066.
8. Klein L, Hinterberger M, Wirnsberger G., Kyewski B. Antigen presentation in the thymus for positive selection and central tolerance induction. Nat Rev Immunol. 2009; 9(12): 833-844.
9. Rossi SW, Jeker LT, Ueno T, et al. Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells. Blood. 2007; 109(9): 3803-3811. (Pubitemid 46641731)
10. Miyara M, Yoshioka Y, Kitoh A., et al. Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor. Immunity. 2009; 30(6): 899-911.