KN-93, A CaMKII inhibitor, suppresses ventricular arrhythmia induced by LQT2 without decreasing TDR

Journal of Huazhong University of Science and Technology - Medical Science

Volumn 33, Issue 5, 2013, Pages 636-639

  Wang, Wen Long ^a   Zhang, Shuang Shuang ^a   Deng, Jie ^b   Zhao, Jun Yan ^a   Zhao, Chong Qiang ^a   Lin, Li ^a   Zhang, Cun Tai ^a   Lv, Jia Gao ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

early afterdepolarization; Torsades de pointes; KN 93; long QT syndrome; transmural dispersion of repolarization

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; ANTIARRHYTHMIC AGENT; BENZYLAMINE DERIVATIVE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; PIPERIDINE DERIVATIVE; PROTEIN KINASE INHIBITOR; PYRIDINE DERIVATIVE; SULFONAMIDE;

ACTION POTENTIAL; ANIMAL; ARTICLE; DRUG ANTAGONISM; DRUG EFFECT; ELECTROCARDIOGRAPHY; ENDOCARDIUM; HEART; HEART ARRHYTHMIA; HEART FUNCTION TEST; IN VITRO STUDY; LONG QT SYNDROME; METABOLISM; PATHOPHYSIOLOGY; PERICARDIUM; RABBIT; TORSADE DES POINTES;

ACTION POTENTIALS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIAS, CARDIAC; BENZYLAMINES; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; ENDOCARDIUM; HEART; LONG QT SYNDROME; PERICARDIUM; PIPERIDINES; PROTEIN KINASE INHIBITORS; PYRIDINES; RABBITS; SULFONAMIDES; TORSADES DE POINTES;

EID: 84886310592     PISSN: 16720733     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11596-013-1172-1     Document Type: Article

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