Adipose tissue: Another target organ for lead accumulation? A study on sardinian children (Italy)

American Journal of Human Biology

Volumn 25, Issue 6, 2013, Pages 789-794

  Vallascas, Elisabetta ^a   De Micco, Alessandro ^a   Deiana, Fabrizio ^a   Banni, Sebastiano ^a   Sanna, Emanuele ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; LEAD;

ADOLESCENT; ANTHROPOMETRY; ARTICLE; CHILD; CROSS-SECTIONAL STUDY; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; EVALUATION STUDY; FEMALE; HAIR; HUMAN; ITALY; MALE; METABOLISM; METHODOLOGY; OBESITY; POLLUTANT; RISK FACTOR;

ADIPOSITY; ADOLESCENT; ANTHROPOMETRY; BIOLOGICAL MARKERS; CHILD; CROSS-SECTIONAL STUDIES; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; ENVIRONMENTAL POLLUTANTS; FEMALE; HAIR; HUMANS; ITALY; LEAD; MALE; RISK FACTORS;

EID: 84886304832     PISSN: 10420533     EISSN: 15206300     Source Type: Journal    
DOI: 10.1002/ajhb.22448     Document Type: Article

References (85)

1. Abadin HG, Pohl HR. 2010. Alkyllead compounds and their environmental toxicology. Met Ions Life Sci 7:153-164.
2. Ahamed M, Siddiqui MKJ. 2007. Environmental lead toxicity and nutritional factors. Clin Nutr 26:400-408.
3. Anderson HA. 1985. Utilization of adipose tissue biopsy in characterizing human halogenated hydrocarbon exposure. Environ Health Perspect 60:127-131.
4. Arrebola JP, Cuellar M, Claure E, Quevedo M, Antelo SR, Mutch E, Ramirez E, Fernandez MF, Olea N, Mercado LA. 2012. Concentrations of organochlorine pesticides and polychlorinated biphenyls in human serum and adipose tissue from Bolivia. Environ Res 112:40-47.
5. ATSDR. 2007. Toxicological profile for lead. Agency for Toxic Substances and Disease Registry. Division of Toxicology and Environmental Medicine/Applied Toxicology Branch. Atlanta, Georgia. Available at: http://www.atsdr.cdc.gov/ToxProfiles/tp13.pdf.
6. Bouchard MF, Bellinger DC, Weuve J, Matthews-Bellinger J, Gilman SE, Wright RO, Schwartz J, Weisskopf MG. 2009. Blood lead levels and major depressive disorder, panic disorder, and generalized anxiety disorder in US young adults. Arch Gen Psychiatry 66:1313-1319.
7. Brambilla P, Bedogni G, Moreno LA, Goran MI, Gutin B, Fox KR, Peters DM, Barbeau P, De Simone M, Pietrobelli A. 2006. Crossvalidation of anthropometry against magnetic resonance imaging for the assessment of visceral and subcutaneous adipose tissue in children. Int J Obes 30:23-30.
8. Brauner EV, Raaschou-Nielsen O, Gaudreau E, Leblanc A, Tjonneland A, Overvad K, Sorensen M. 2012. Predictors of adipose tissue concentrations of organochlorine pesticides in a general Danish population. J Expo Sci Environ Epidemiol 22:52-59.
9. Carlisle JC, Dowling KC, Siegel DM, Alexeeff GV. 2009. A blood lead benchmark for assessing risks from childhood lead exposure. J Environ Sci Health A Tox Hazard Subst Environ Eng 44:1200-1208.
10. Chlopicka J, Zagrodzki P, Zachwieji Z, Krosniak M, Folta M. 1995. Use of pattern recognition method in the interpretation of heavy metal content (lead and cadmium) in children's scalp hair. Analyst 120:943-945.
11. Chlopicka J, Zachwieja Z, Zagrodzki P, Frydrych J, Slota P, Krosniak M. 1998. Lead and cadmium in the hair and blood of children from a highly industrial area in Poland. Biol Trace Elem Res 62:229-234.
12. Covaci A, deBoer J, Ryan JJ, Voorspoels S, Schepens P. 2002. Distribution of organobrominated and organochlorinated contaminants in Belgian human adipose tissue. Environm Res Section 88:210-218.
13. Denham M, Schell LM, Deane G, Gallo MV, Ravenscroft J, DeCaprio AP; Akwesasne Task Force on the Environment. 2005. Relationship of lead, mercury, mirex, dichlorodiphenyldichloroethylene, hexachlorobenzene, and polychlorinated biphenyls to timing of menarche among Akwesasne Mohawk girls. Pediatrics 115:127-134.
14. Dioka CE, Orisakwe OE, Adeniyi FAA, Meludu SC. 2004. Liver and renal function tests in artisans occupationally exposed to lead in mechanic village in Nnewi, Nigeria. Int J Environ Res Public Health 1:21-25.
15. Dooyema CA, Neri A, Lo Y-C, Durant J, Dargan PI, Swarthout T, Biya O, Gidado SO, Haladu S, Sani-Gwarzo N, et al. 2012. Outbreak of fatal childhood lead poisoning related to artisanal gold mining in Northwestern Nigeria, 2010. Environ Health Perpect 120:1-31.
16. El-Dereny M, Rashwan NI. 2011. Solving multicollinearity problem using ridge regression models. Int J Contemp Math Sci 12:585-600.
17. Ersoy B, Balkan C, Gunay T, Egemen A. 2005. The factors affecting the relation between the menarcheal age of mother and daughter. Child Care Health Dev 31:303-308.
18. Eveleth PB. Tanner JM. 1990. Worldwide variation in human growth, Cambridge: Cambridge University Press.
19. Factor-Litvak P, Wasserman G, Kline JK, Graziano J. 1999. The Yugoslavia Prospective Study of environmental lead exposure. Environ Health Perspect 107:9-15.
20. Frisancho AR. 1990. Anthropometric standard for the assessment of growth and nutritional status, Ann Arbor MI: The University of Michigan Press.
21. Fullmer CS. 1992. Intestinal interactions of lead and calcium. Neurotoxicol 13:799-807.
22. Goodman LS. Gilman A. 2005. Le basi farmacologiche della terapia, Ed McGraw-Hill.
23. Hauser R, Sergeyev O, Korrick S, Lee MM, Revich B, Gitin E, Burns JS, Williams PL. 2008. Association of blood lead levels with onset of puberty in Russian boys. Environ Health Perspec 116:976-980.
24. Haynes EN, Kalkwarf HJ, Hornung R, Wenstrup R, Dietrich K, Lanphear BP. 2003. Vitamin D receptor Fok1 polymorphism and blood lead concentration in children. Environ Health Perspect 111:1665-1669.
25. Hong NS, Kim KS, Lee IK, Lind PM, Lind L, Jacobs DR, Lee DH. 2012. The association between obesity and mortality in the elderly differs by serum concentrations of persistent organic pollutants: A possible explanation for the obesity paradox. Int J Obes 36:1170-1175.
26. Hu H, Shih R, Rothenberg S, Schwartz BS. 2007. The epidemiology of lead toxicity in adults: Measuring dose and consideration of other methodologic issues. Environ Health Perspect 115:455-462.
27. Iglesias V, Steenland K, Maisonet M, Pino P. 2011. Exposure to lead from a storage site associated with intellectual impairment in Chilean children living nearby. Int J Occup Environ Health 17:314-321.
28. Ignasiak Z, Slawinska T, Rozek K, Little BB, Malina RM. 2006. Lead and growth status of schoolchildren living in the copper basin of south-western Poland: differential effects on bone growth. Ann Human Biol 33:401-414.
29. Ignasiak Z, Slawinska T, Rozek K, Malina R, Little BB. 2007. Blood lead level and physical fitness of schoolchildren in the copper basin of south-western Poland: indirect effects through growth stunting. Ann Human Biol 34:329-343.
30. Jacob B, Ritz B, Heinrich J, Hoelscher B, Wichmann HE. 2000. The effect of low-level blood lead on hematologic parameters in children. Environ Res 82:150-159.
31. Järup L. 2003. Hazards of heavy metal contamination. Br Med Bull 68:167-182.
32. Kapka L, Baumgartner A, Siwinska E, Knudsen LE, Anderson D, Mielzynska D. 2007. Environmental lead exposure increases micronuclei in children. Mutagen 22:201-207.
33. Kim MJ, Marchand P, Henegar C, Antignac J-P, Alili R, Poitou C, Bouillot J-L, Basdevant A, LeBizec B, Barouki R, et al. 2011. Fate and complex pathogenic effects of dioxins and polychlorinated biphenyls in obese subjects before and after drastic weight loss. Environ Health Perspect 119:377-383.
34. Lata S, Wiernikowski A, Soldatow E. 1999. Psychiatric disorders during acute tetraethyl lead poisoning in a woman with hyperthyroidism. Przegl Lek 56:469-471.
35. Lech T. 2002. Lead, copper, zinc, and magnesium content in hair of children and young people with some neurological diseases. Biol Trace Elem Res 85:111-126.
36. Lidsky TI, Schneider JS. 2003. Lead neurotoxicity in children: basic mechanisms and clinical correlates. Brain 126:5-19.
37. Liu J, McCauley L, Compher C, Yan C, Shen X, Needleman H, Pinto-Martin JA. 2011. Regular breakfast and blood lead levels among preschool children. Environ Health 10:10-28.
38. Lohman TG, Roche AF, Martorell R. 1988. Anthropometric standardization reference manual, Human Kinetics Books: Champaign, IL.
39. Mangas S, Fitzgerald J. 2003. Exposures to lead require ongoing vigilance. Bull Word Health Organ 81:847.
40. Marchetti C. 2003. Molecular targets of lead in brain neurotoxicity. Neurotox Res 5:221-236.
41. Marti-Cid R, Bocio A, Llobet JM, Domingo JL. 2007. Intake of chemical contaminants through fish and seafood consumption by children of Catalonia, Spain: Health risks. Food Chem Toxicol 45:1968-1974.
42. Martin R, Saller K. 1957. Lehrbuch der anthropologie, Stuttgart: Fisher Verlag.
43. Mascie-Taylor CG, Boldsen JL. 1985. Regional and social analysis of height variation in a contemporary British sample. Ann Hum Biol 12:315-324.
44. Meyer PA, Brown MJ, Falk H. 2008. Global approach to reducing lead exposure and poisoning. Mutat Res 659:166-175.
45. Muellerova D, Kopecky J. 2007. White adipose tissue: storage and effector site for environmental pollutants. Physiol Res 56:375-381.
46. Naicker N, Norris SA, Mathee A, Becker P, Richter L. 2010. Lead exposure is associated with a delay in the onset of puberty in South African adolescent females: findings from the Birth to Twenty cohort. Sci Total Environ 408:4949-4954.
47. Nie LH, Wright RO, Bellinger DC, Hussain J, Amarasiriwardena C, Chettle DR, Pejovic-Milic A, Woolf A, Shannon M. 2011. Blood lead levels and cumulative blood lead index (CBLI) as predictors of late neurodevelopment in lead poisoned children. Biomarkers 16:517-524.
48. Nowak B, Chmielnicka J. 2000. Relationship of lead and cadmium to essential elements in hair, teeth, and nails of environmentally exposed people. Ecotoxicol Environ Saf 46:265-274.
49. Olympio KP, Gonçalves C, Günther WM, Bechara J. 2009. Neurotoxicity and aggressiveness triggered by low-level lead in children: a review. Rev Panam Salud Publica 26:266-275.
50. Perelló G, Marti-Cid R, Llobet JM, Domingo JL. 2008. Effects of various cooking processes on the concentrations of arsenic, cadmium, mercury, and lead in foods. J Agric Food Chem 56:1262-1269.
51. Rahman A, Maqbool E, Zuberi HS. 2002. Lead-associated deficits in stature, mental ability and behaviour in children in Karachi. Ann Trop Paediatr 22:301-311.
52. Rai A, Maurya SK, Khare P, Srivastava A, Bandyopadhyay S. 2010. Characterization of developmental neurotoxicity of As, Cd, and Pb mixture: synergistic action of metal mixture in glial and neuronal functions. Toxicol Sci 118:586-601.
53. Rodrigues JL, Batista BL, Nunes JA, Passos CJS, Barbosa F, Jr. 2008. Evaluation of the use of human hair for biomonitoring the deficiency of essential and exposure to toxic elements. Sci Total Environ 405:370-376.
54. Roy A, Bellinger D, Hu H, Schwartz J, Ettinger AS, Wright RO, Bouchard M, Palaniappan K, Balakrishnan K. 2009. Lead exposure and behavior among young children in Chennai, India. Environ Health Perspect 117:1607-1611.
55. Sanders T, Liu Y, Buchner V, Tchounwou PB. 2009. Neurotoxic effects and biomarkers of lead exposure: a review. Rev Environ Health 24:15-45.
56. Sanna E, Liguori A, Palmas L, Soro MR, Floris G. 2003. Blood and hair lead levels in boys and girls living in two Sardinian towns at different risks of lead pollution. Ecotoxicol Environ Saf 55:293-299.
57. Sanna E, Vargiu L, Rossetti I, Vallascas E, Floris G. 2007. Correlation between blood and hair lead levels in boys and girls of Sardinia (Italy). J Anthropol Sci 85:173-181.
58. Sanna E, Floris G, Vallascas E. 2008. Town and gender effects on hair lead levels in children from three Sardinian towns (Italy) with different environmental backgrounds. Biol Trace Elem Res 124:52-59.
59. Sanna E, Vallascas E. 2011. Hair lead levels to evaluate the subclinical impact of lead on growth in Sardinian Children (Italy). Am J Hum Biol 23:740-746.
60. Schell LM, Denham M, Stark AD, Parsons PJ, Schulte EE. 2009. Growth of infants' length, weight, head and arm circumferences in relation to low levels of blood lead measured serially. Am J Hum Biol 21:180-187.
61. Schell LM, Gallo MV, Cook K. 2012. What's NOT to eat-food adulteration in the context of human biology. Am J Hum Biol 24:139-148.
62. Schildkraut JM, Demark-Wahnefried W, DeVoto E, Hughes C, Laseter JL, Newman B. 1999. Environmental contaminants and body fat distribution. Cancer Epidemiol Biomarkers Prev 8:179-183.
63. Schwartz BS, Stewart WF, Kelsey KT, Simon D, Park S, Links JM, Todd AC. 2000. Associations of tibial lead levels with BsmI polymorphisms in the vitamin D receptor in former organolead manufacturing workers. Environ Health Perspec 108:199-203.
64. Schwartz J, Angle C, Pitcher H. 1986. Relationship between childhood blood lead levels and stature. Pediatrics 77:281-288.
65. Simoes AM, Duarte FV, Teodoro JS, Rolo AP, Palmeira CM. 2010. Exposure to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin and tetraethyl lead affects lung mitochondria bioenergetics. Toxicol Mech Methods 20:199-203.
66. Stupar J, Dolinsek F, Erzen I. 2007. Hair-Pb longitudinal profiles and blood-Pb in the population of young Slovenian males. Ecotoxicol Environ Saf 68:134-143.
67. Szkup-Jablonska M, Karakiewicz B, Grochans E, Jurczak A, Zaremba-Pechmann L, Rotter I, Nowak-Starz G, Samochowiec J. 2011. The effects of lead level in the blood on social functioning in children with developmental disabilities. Psychiatric Pol 45:713-722.
68. Tait PA, Vora A, James S, Fitzgerald DJ, Pester BA. 2002. Severe congenital lead poisoning in a preterm infant due to a herbal remedy. Medical Journal of Australia 177:193-195.
69. Tenenbein M. 1997. Leaded gasoline abuse: the role of tetraethyl lead. Hum Exp Toxicol 16:217-222.
70. Theppeang K, Glass TA, Bandeen-Roche K, Todd AC, Rohde CA, Links JM, Schwartz BS. 2008. Associations of bone mineral density and lead levels in blood, tibia, and patella in urban-dwelling women. Environ Health Perspec 116:784-790.
71. Tomoum HY, Mostafa GA, Ismail NA, Ahmed SM. 2010. Lead exposure and its association with pubertal development in school-age Egyptian children: pilot study. Pediatr Int 52:89-93.
72. Tong IS, Lu Y. 2001. Identification of confounders in the assessment of the relationship between lead exposure and child development. Ann Epidemiol 11:38-45.
73. Waliszewski SM, Sanchez K, Caba M, Saldariaga-Norena H, Meza E, Zepeda R, Valencia Quintana R, Infanzon R. 2012. Organochlorine pesticide levels in female adipose tissue from Puebla, Mexico. Bull Environ Contam Toxicol 88:296-301.
74. Wang Q, Luo W, Zheng W, Liu Y, Xu H, Zheng G, Dai Z, Zhang W, Chen Y, Chen J. 2007. Iron supplement prevents lead-induced disruption of the blood-brain barrier during rat development. Toxical Appl Pharmacol 219:33-41.
75. White LD, Cory-Slechta DA, Gilbert ME, Tiffany-Castiglioni E, Zawia NH, Virgolini M, Rossi-George A, Lasley SM, Qian YC, Basha MR. 2007. New and evolving concepts in the neurotoxicology of lead. Toxical Appl Pharmacol 225:1-27.
76. Wilhelm M, Pesch A, Rostek U, Begerow J, Schmitz N, Idel H, Ranft U. 2002. Concentrations of lead in blood, hair and saliva of German children living in three different areas of traffic density. Sci Total Environ 297:109-118.
77. Williams PL, Sergeyev O, Lee MM, Korrick SA, Burns JS, Humblet O, DelPrato J, Revich B, Hauser R. 2010. Blood lead levels and delayed onset of puberty in a longitudinal study of Russian boys. Pediatrics 125:1088-1096.
78. Wills BK, Christensen J, Mazzoncini J, Miller M. 2010. Severe neurotoxicity following ingestion of tetraethyl lead. J Med Toxicol 6:31-34.
79. Winnik L, Radomska M, Szczepanska L, Pach D, Hubalewska A. 2004. Diagnostic problems in case of environmental exposure to tetraethyl lead. Przegl Lek 61:361-365.
80. Wolff MS, Anderson HA, Britton JA, Rothman N. 2007. Pharmacokinetic variability and modern epidemiology-the example of dichlorodiphenyltrichloroethane, body mass index, and birth cohort. Cancer Epidemiol Biomarkers Prev 16:1925-1930.
81. World Health Organization (WHO). 2010a. Preventing disease through healthy environments. Available at: http://www.who.int/ipcs/features/10chemicals_en.pdf.
82. World Health Organization (WHO). 2010b. Childhood Lead Poisoning. Available at: http://www.who.int/ceh/publications/leadguidance.pdf.
83. Wright RO, Shannon MW, Wright RJ, Hu H. 1999. Association between iron deficiency and low-level lead poisoning in an urban primary care clinic. Am J Public Health 89:1049-1053.
84. Yu GW, Laseter J, Mylander C. 2011. Persistent organic pollutants in serum and several different fat compartments in humans. J Environ Public Health 2011:417980.
85. Zhang A, Hu H, Sanchez BN, Ettinger AS, Park SK, Cantonwine D, Schnaas L, Wright RO, Lamadrid-Figueroa H, Maria Tellez-Rojo M. 2012. Association between prenatal lead exposure and blood pressure in children. Environ Health Perspect 120:445-450.