Cognitive problems in patients on androgen deprivation therapy: A qualitative pilot study

Urologic Oncology: Seminars and Original Investigations

Volumn 31, Issue 8, 2013, Pages 1533-1538

  Wu, Lisa M ^a   Diefenbach, Michael A ^a   Gordon, Wayne A ^a   Cantor, Joshua B ^a   Cherrier, Monique M ^b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Androgen deprivation therapy; Cognitive function; Neurobehavioral function; Neuropsychology; Oncology; Prostate cancer; Rehabilitation

Indexed keywords

ADULT; AGED; ANDROGEN DEPRIVATION THERAPY; APATHY; ARTICLE; ASTHENIA; CANCER PATIENT; CANCER THERAPY; CLINICAL ARTICLE; COGNITIVE DEFECT; DEPTH PERCEPTION; FATIGUE; HUMAN; INFORMATION PROCESSING; MALE; MEMORY; MENTAL CONCENTRATION; ONLINE SYSTEM; OUTCOME ASSESSMENT; PILOT STUDY; PRIORITY JOURNAL; PROSTATE CANCER; QUALITATIVE RESEARCH; THERAPY EFFECT; TREATMENT OUTCOME; VERBAL BEHAVIOR; VERBAL MEMORY; VISUAL INFORMATION; VISUAL MEMORY;

ANDROGEN DEPRIVATION THERAPY; COGNITIVE FUNCTION; NEUROBEHAVIORAL FUNCTION; NEUROPSYCHOLOGY; ONCOLOGY; PROSTATE CANCER; REHABILITATION;

ADULT; AGED; ANDROGEN ANTAGONISTS; ANTINEOPLASTIC AGENTS, HORMONAL; COGNITION; COGNITION DISORDERS; HEALTH SURVEYS; HUMANS; INTERVIEWS AS TOPIC; MALE; MIDDLE AGED; PILOT PROJECTS; PROSTATIC NEOPLASMS;

EID: 84886294863     PISSN: 10781439     EISSN: 18732496     Source Type: Journal    
DOI: 10.1016/j.urolonc.2012.07.003     Document Type: Article

References (30)

1. Sharifi N., Gulley J.L., Dahut W.L. Androgen deprivation therapy for prostate cancer. JAMA 2005, 294:238-244.
2. Nelson C.J., Lee J.S., Gamboa M.C., et al. Cognitive effects of hormone therapy in men with prostate cancer: A review. Cancer 2008, 113:1097-1106.
3. Janowsky J.S. The role of androgens in cognition and brain aging in men. Neuroscience 2006, 138:1015-1020.
4. Davidson J.M., Chen J.J., Crapo L., et al. Hormonal changes and sexual function in aging men. J Clin Endocrinol Metab 1983, 57:71-77.
5. Vermeulen A. Clinical review 24: Androgens in the aging male. J Clin Endocrinol Metab 1991, 73:221-224.
6. Jamadar R.J., Winters M.J., Maki P.M. Cognitive changes associated with ADT: A review of the literature. Asian J Androl 2012, 14:232-238.
7. Linn M.C., Petersen A.C. Emergence and characterization of sex differences in spatial ability: A meta-analysis. Child Dev 1985, 56:1479-1498.
8. Chan R.C., Shum D., Toulopoulou T., et al. Assessment of executive functions: Review of instruments and identification of critical issues. Arch Clin Neuropsychol 2008, 23:201-216.
9. Cherrier M.M., Aubin S., Higano C.S. Cognitive and mood changes in men undergoing intermittent combined androgen blockade for non-metastatic prostate cancer. Psychooncology 2009, 18:237-247.
10. Jim H.S., Small B.J., Patterson S., et al. Cognitive impairment in men treated with luteinizing hormone-releasing hormone agonists for prostate cancer: A controlled comparison. Support Care Cancer 2009, 18:21-27.
11. Mohile S.G., Lacy M., Rodin M., et al. Cognitive effects of androgen deprivation therapy in an older cohort of men with prostate cancer. Crit Rev Oncol Hematol 2010, 75:152-159.
12. Alibhai S.M., Breunis H., Timilshina N., et al. Impact of androgen-deprivation therapy on physical function and quality of life in men with nonmetastatic prostate cancer. J Clin Oncol 2010, 28:5038-5045.
13. Ahles T.A., Saykin A.J., McDonald B.C., et al. Longitudinal assessment of cognitive changes associated with adjuvant treatment for breast cancer: Impact of age and cognitive reserve. J Clin Oncol 2010, 28:4434-4440.
14. Lyketsos C.G., Toone L., Tschanz J., et al. Population-based study of medical comorbidity in early dementia and "cognitive impairment, no dementia (CIND)": Association with functional and cognitive impairment: The cache county study. Am J Geriatr Psychiatry 2005, 13:656-664.
15. Joly F., Alibhai S.M., Galica J., et al. Impact of androgen deprivation therapy on physical and cognitive function, as well as quality of life of patients with nonmetastatic prostate cancer. J Urol 2006, 176:2443-2447.
16. Voerman B., Fischer M., Visser A., et al. Health-related quality of life in Dutch men with prostate cancer. J Psychosoc Oncol 2006, 24:49-64.
17. Shilling V., Jenkins V. Self-reported cognitive problems in women receiving adjuvant therapy for breast cancer. Eur J Oncol Nurs 2007, 11:6-15.
18. Marcotte T.D., Scott J.D., Kamat R., et al. Neuropsychology and the prediction of everyday functioning. Neuropsychology of everyday functioning 2010, 5-38. Guilford Publications, New York. T.D. Marcotte, I. Grant (Eds.).
19. Kvale S., Brinkmann S. Interviews: Learning the craft of qualitative research interviewing 2008, Sage Publications, Thousand Oaks, CA.
20. Kidd S.A. The role of qualitative research in psychological journals. Psychol Methods 2002, 7:126-138.
21. Ferguson R.J., Ahles T.A., Saykin A.J., et al. Cognitive-behavioral management of chemotherapy-related cognitive change. Psychooncology 2007, 16:772-777.
22. Cicerone K.D., Dahlberg C., Malec J.F., et al. Evidence-based cognitive rehabilitation: Updated review of the literature from 1998 through 2002. Arch Phys Med Rehabil 2005, 86:1681-1692.
23. Helmick K. Cognitive rehabilitation for military personnel with mild traumatic brain injury and chronic post-concussional disorder: Results of Apr 2009 consensus conference. NeuroRehabilitation 2010, 26:239-255. Members of Consensus Conference.
24. Sohlberg M.M., Mateer C.A. Cognitive rehabilitation: An integrative neuropsychological approach 2001, Guilford Publications, New York.
25. Hillman C.H., Erickson K.I., Kramer A.F., et al. Be smart, exercise your heart: Exercise effects on brain and cognition. Nat Rev Neurosci 2008, 9:58-65.
26. Fardell J.E., Vardy J., Shah J.D., et al. Cognitive impairments caused by oxaliplatin and 5-fluorouracil chemotherapy are ameliorated by physical activity. Psychopharmacology (Berl) 2012, 220:183-193.
27. Beer T.M., Bland L.B., Bussiere J.R., et al. Testosterone loss and estradiol administration modify memory in men. J Urol 2006, 175:130-135.
28. Taxel P., Luthra P., Fall P.M., et al. The effect of short-term estradiol therapy on clotting and inflammatory markers in older men receiving hormonal suppression therapy for prostate cancer. Aging Male 2008, 11:71-75.
29. Matousek R.H., Sherwin B.B. A randomized controlled trial of add-back estrogen or placebo on cognition in men with prostate cancer receiving an antiandrogen and a gonadotropin-releasing hormone analog. Psychoneuroendocrinology 2010, 35:215-225.
30. Mols F., Thong M.S., Vreugdenhil G., et al. Long-term cancer survivors experience work changes after diagnosis: Results of a population-based study. Psychooncology 2009, 18:1252-1260.