Heat shock protein inducer modifies arrhythmogenic substrate and inhibits atrial fibrillation in the failing heart

International Journal of Cardiology

Volumn 168, Issue 4, 2013, Pages 4019-4026

  Chang, Shih Lin ^a,b   Chen, Yao Chang ^c   Hsu, Chiao Po ^a,b   Kao, Yu Hsun ^d,e   Lin, Yung Kuo ^d,e   Lai, Yu Jun ^f   Yeh, Hung I ^f   Higa, Satoshi ^g   Chen, Shih Ann ^a,b   Chen, Yi Jen ^d,e  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^f MACKAY MEMORIAL HOSPITAL   (Taiwan)

^g Makiminato Central Hospital   (Japan)

Author keywords

Atrial fibrillation; GGA; Heart failure; Heat shock protein; Monophasic action potential

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL CAV1.2; HEAT SHOCK PROTEIN; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1; ION CHANNEL; MESSENGER RNA; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SODIUM CHANNEL; SODIUM CHANNEL NAV1.4; SODIUM CHANNEL NAV1.5; SODIUM CHANNEL NAV1.7; SODIUM CHANNEL NAV11.1; TEPRENONE; UNCLASSIFIED DRUG; DITERPENE;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARRHYTHMOGENESIS; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DRUG ACTIVITY; DRUG EFFICACY; ELECTRIC CONDUCTIVITY; ELECTRODE; HEART ATRIUM FIBRILLATION; HEART CONTRACTION; HEART ELECTROPHYSIOLOGY; HEART FAILURE; HEART LEFT ATRIUM; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; UPREGULATION; WESTERN BLOTTING; AGONISTS; ANIMAL; ATRIAL FIBRILLATION; BIOSYNTHESIS; DRUG EFFECTS; PATHOPHYSIOLOGY; PHYSIOLOGY; RABBIT;

ACTION POTENTIALS; ANIMALS; ATRIAL FIBRILLATION; DITERPENES; HEART FAILURE; HEAT-SHOCK PROTEINS; RABBITS;

EID: 84886262508     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2013.06.072     Document Type: Article

References (22)

1. O. Wakisaka, N. Takahashi, and T. Shinohara Hyperthermia treatment prevents angiotensin II-mediated atrial fibrosis and fibrillation via induction of heat-shock protein 72 J Mol Cell Cardiol 43 2007 616 626
2. B.J. Brundel, A. Shiroshita-Takeshita, and X. Qi Induction of heat shock response protects the heart against atrial fibrillation Circ Res 99 2006 1394 1402
3. K.M. Lin, B. Lin, I.Y. Lian, R. Mestril, I.E. Scheffler, and W.H. Dillmann Combined and individual mitochondrial HSP60 and HSP10 expression in cardiac myocytes protects mitochondrial function and prevents apoptotic cell deaths induced by simulated ischemia-reoxygenation Circulation 103 2001 1787 1792
4. J. Liu, K.W. Kam, G.H. Borchert, G.M. Kravtsov, H.J. Ballard, and T.M. Wong Further study on the role of HSP70 on Ca2 + homeostasis in rat ventricular myocytes subjected to simulated ischemia Am J Physiol Cell Physiol 290 2006 C583 C591
5. Y.C. Chen, Y.H. Kao, C.F. Huang, C.C. Cheng, Y.J. Chen, and S.A. Chen Heat stress responses modulate calcium regulations and electrophysiological characteristics in atrial myocytes J Mol Cell Cardiol 48 2010 781 788
6. Y.K. Lin, M.S. Lai, and Y.C. Chen Hypoxia and reoxygenation modulate the arrhythmogenic activity of the pulmonary vein and atrium Clin Sci (Lond) 122 2012 121 132
7. T. Hirakawa, K. Rokutan, T. Nikawa, and K. Kishi Geranylgeranylacetone induces heat shock proteins in cultured guinea pig gastric mucosal cells and rat gastric mucosa Gastroenterology 111 1996 345 357
8. T. Ooie, N. Takahashi, and T. Saikawa Single oral dose of geranylgeranylacetone induces heat-shock protein 72 and renders protection against ischemia/reperfusion injury in rat heart Circulation 104 2001 1837 1843
9. B.J. Brundel, R.H. Henning, L. Ke, I.C. van Gelder, H.J. Crijns, and H.H. Kampinga Heat shock protein upregulation protects against pacing-induced myolysis in HL-1 atrial myocytes and in human atrial fibrillation J Mol Cell Cardiol 41 2006 555 562
10. S.L. Chang, Y.C. Chen, and Y.H. Yeh Heart failure enhanced pulmonary vein arrhythmogenesis and dysregulated sodium and calcium homeostasis with increased calcium sparks J Cardiovasc Electrophysiol 22 2011 1378 1386
11. M.P. Pye, M. Black, and S.M. Cobbe Comparison of in vivo and in vitro haemodynamic function in experimental heart failure: use of echocardiography Cardiovasc Res 31 1996 873 881
12. M.R. Franz Current status of monophasic action potential recording: theories, measurements and interpretations Cardiovasc Res 41 1999 25 40
13. B. Koller, and M.R. Franz New classification of moricizine and propafenone based on electrophysiologic and electrocardiographic data from isolated rabbit heart J Cardiovasc Pharmacol 24 1994 753 760
14. J.N. Weiss, P.S. Chen, Z. Qu, H.S. Karagueuzian, S.F. Lin, and A. Garfinkel Electrical restitution and cardiac fibrillation J Cardiovasc Electrophysiol 13 2002 292 295
15. S.M. Narayan, D. Kazi, D.E. Krummen, and W.J. Rappel Repolarization and activation restitution near human pulmonary veins and atrial fibrillation initiation: a mechanism for the initiation of atrial fibrillation by premature beats J Am Coll Cardiol 52 2008 1222 1230
16. M. Sakabe, A. Shiroshita-Takeshita, and A. Maguy Effects of a heat shock protein inducer on the atrial fibrillation substrate caused by acute atrial ischaemia Cardiovasc Res 78 2008 63 70
17. I.J. Benjamin, and D.R. McMillan Stress (heat shock) proteins: molecular chaperones in cardiovascular biology and disease Circ Res 83 1998 117 132
18. P. James, M. Inui, M. Tada, M. Chiesi, and E. Carafoli Nature and site of phospholamban regulation of the Ca2 + pump of sarcoplasmic reticulum Nature 342 1989 90 92
19. A. Mattiazzi, C. Mundina-Weilenmann, C. Guoxiang, L. Vittone, and E. Kranias Role of phospholamban phosphorylation on Thr17 in cardiac physiological and pathological conditions Cardiovasc Res 68 2005 366 375
20. C. Mundina-Weilenmann, L. Vittone, M. Ortale, G.C. de Cingolani, and A. Mattiazzi Immunodetection of phosphorylation sites gives new insights into the mechanisms underlying phospholamban phosphorylation in the intact heart J Biol Chem 271 1996 33561 33567
21. C.T. Tsai, F.T. Chiang, and C.D. Tseng Mechanical stretch of atrial myocyte monolayer decreases sarcoplasmic reticulum calcium adenosine triphosphatase expression and increases susceptibility to repolarization alternans J Am Coll Cardiol 58 2011 2106 2115
22. 2 +-ATPase in patients with advanced heart failure Circulation 124 2011 304 313