Modeling respiratory Syncytial virus Cytopathogenesis in the human airway

American Journal of Respiratory and Critical Care Medicine

Volumn 188, Issue 7, 2013, Pages 766-767

  Tripp, Ralph A ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CXCL11 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 6; INTERLEUKIN 8;

AIRWAY; BRONCHUS MUCOSA; CYTOKINE RELEASE; CYTOPATHOLOGY; EDITORIAL; LOWER RESPIRATORY TRACT INFECTION; LUNG LAVAGE; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY SYNCYTIAL VIRUS INFECTION; VIRUS CELL INTERACTION; VIRUS PATHOGENESIS; VIRUS REPLICATION;

BRONCHI; HUMANS; NASAL MUCOSA; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY TRACT INFECTIONS;

EID: 84886260665     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201308-1491ED     Document Type: Editorial

References (18)

1. Thorburn K, Eisenhut M, Riordan A. Mortality and morbidity of nosocomial respiratory syncytial virus (RSV) infection in ventilated children- a ten year perspective. Minerva Anestesiol 2012;78:782.
2. Deshpande S.A., Northern V. The clinical and health economic burden of respiratory syncytial virus disease among children under 2 years of age in a defined geographical area. Arch Dis Child 2003;88:1065-1069. (Pubitemid 38064480)
3. Hon KL, Leung TF, Cheng WY, Ko NM, Tang WK, Wong WW, Yeung WH, Chan PK. Respiratory syncytial virus morbidity, premorbid factors, seasonality, and implications for prophylaxis. J Crit Care 2012;27:464-468.
4. Kao YJ, Piedra PA, Larsen GL, Colasurdo GN. Induction and regulation of nitric oxide synthase in airway epithelial cells by respiratory syncytial virus. Am J Respir Crit Care Med 2001;163:532-539. (Pubitemid 32158541)
5. Noah TL, Becker S. Respiratory syncytial virus-induced cytokine production by a human bronchial epithelial cell line. Am J Physiol 1993;265:L472-L478.
6. Bem R.A., Domachowske JB, Rosenberg HF. Animal models of human respiratory syncytial virus disease. Am J Physiol Lung Cell Mol Physiol 2011;301:L148-L156.
7. Johnson JE, Gonzales R.A., Olson SJ, Wright PF, Graham BS. The histopathology of fatal untreated human respiratory syncytial virus infection. Mod Pathol 2007;20:108-119. (Pubitemid 44967956)
8. Jewell NA, Cline T, Mertz SE, Smirnov SV, Flaño E, Schindler C, Grieves JL, Durbin RK, Kotenko SV, Durbin JE. Lambda interferon is the predominant interferon induced by influenza A virus infection in vivo. J Virol 2010;84:11515-11522.
9. Villenave R, Thavagnanam S, Sarlang S, Parker J, Douglas I, Skibinski G, Heaney LG,McKaigue JP, Coyle PV, ShieldsMD, et al. In vitro modeling of respiratory syncytial virus infection of pediatric bronchial epithelium, the primary target of infection in vivo. Proc Natl Acad Sci US.A. 2012;109: 5040-5045.
10. Welliver TP, Garofalo R.P., Hosakote Y, Hintz KH, Avendano L, Sanchez K, Velozo L, Jafri H, Chavez-Bueno S, Ogra PL, et al. Severe human lower respiratory tract illness caused by respiratory syncytial virus and influenza virus is characterized by the absence of pulmonary cytotoxic lymphocyte responses. J Infect Dis 2007;195:1126-1136. (Pubitemid 46543443)
11. Okabayashi T, Kojima T, Masaki T, Yokota S, Imaizumi T, Tsutsumi H, Himi T, Fujii N, Sawada N. Type-III interferon, not type-I, is the predominant interferon induced by respiratory viruses in nasal epithelial cells. Virus Res 2011;160:360-366.
12. Guo-Parke H, Canning P, Douglas I, Villenave R, Heaney LG, Coyle PV, Lyons JD, Shields MD, Power UF. Relative respiratory syncytial virus cytopathogenesis in upper and lower respiratory tract epithelium. Am J Respir Crit Care Med 2013;188:842-851.
13. Wong JY, Rutman A, O'Callaghan C. Recovery of the ciliated epithelium following acute bronchiolitis in infancy. Thorax 2005;60:582-587. (Pubitemid 40966213)
14. Zhang L, Peeples ME, Boucher RC, Collins PL, Pickles RJ. Respiratory syncytial virus infection of human airway epithelial cells is polarized, specific to ciliated cells, and without obvious cytopathology. J Virol 2002;76:5654-5666. (Pubitemid 34517916)
15. Villenave R, ShieldsMD, Power UF. Respiratory syncytial virus interaction with human airway epithelium. Trends Microbiol 2013;21:238-244.
16. Oshansky CM, Zhang W, Moore E, Tripp R.A.. The host response and molecular pathogenesis associated with respiratory syncytial virus infection. Future Microbiol 2009;4:279-297.
17. Hsu AC, Barr I, Hansbro PM, Wark PA. Human influenza is more effective than avian influenza at antiviral suppression in airway cells. Am J Respir Cell Mol Biol 2011;44:906-913
18. Ioannidis I, Ye F, McNally B, Willette M, Flaño E. Toll-like receptor expression and induction of type I and type III interferons in primary airway epithelial cells. J Virol 2013;87:3261-3270.