Pro-Inflammatory Adipokines as Predictors of Incident Cancers in a Chinese Cohort of Low Obesity Prevalence in Hong Kong

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Yeung, Chun Yip ^a   Tso, Annette Wai Kwan ^a   Xu, Aimin ^a   Wang, Yu ^a   Woo, Yu Cho ^a   Lam, Tai Hing ^a   Lo, Su Vui ^b   Fong, Carol Ho Yee ^a   Wat, Nelson Ming Sang ^a   Woo, Jean ^c   Cheung, Bernard Man Yung ^a   Lam, Karen Siu Ling ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b HOSPITAL AUTHORITY   (Hong Kong)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; C REACTIVE PROTEIN; FATTY ACID BINDING PROTEIN 4; INSULIN; INTERLEUKIN 6; LEPTIN; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; TUMOR NECROSIS FACTOR RECEPTOR 2;

ADULT; AGE; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; CANCER INCIDENCE; CANCER RISK; CHINESE; COHORT ANALYSIS; COLORECTAL CANCER; CONTROLLED STUDY; DYSLIPIDEMIA; FEMALE; FEMALE GENITAL TRACT CANCER; HONG KONG; HUMAN; HYPERTENSION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LONGITUDINAL STUDY; LUNG CARCINOMA; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; POPULATION RESEARCH; PREVALENCE; PROSTATE CANCER; PROTEIN BLOOD LEVEL; SEX; SMOKING; WAIST CIRCUMFERENCE;

ADIPOKINES; ADIPOSITY; ASIAN CONTINENTAL ANCESTRY GROUP; FEMALE; HONG KONG; HUMANS; INFLAMMATION; MALE; MIDDLE AGED; NEOPLASMS; OBESITY; PREVALENCE; RISK FACTORS;

EID: 84886245427     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078594     Document Type: Article

References (42)

1. Hossain P, Kawar B, El Nahas M, (2007) Obesity and diabetes in the developing world--a growing challenge. N Engl J Med 356: 213-215. doi:10.1056/NEJMp068177. PubMed: 17229948.
2. World Health Organization, Office of Health Communications and Public Relations (2006) Obesity and overweight. Geneva: World Health Organization. p. pp. 3. p.A paragraph return was deleted.
3. Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M, (2008) Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet 371: 569-578.
4. Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, et al. (2003) Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112: 1796-1808. doi:10.1172/JCI19246. PubMed: 14679176.
5. Neurath MF, Finotto S, (2011) IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer. Cytokine Growth Factor Rev 22: 83-89. doi:10.1016/j.cytogfr.2011.02.003. PubMed: 21377916.
6. Balkwill F, (2006) TNF-alpha in promotion and progression of cancer. Cancer Metastasis Rev 25: 409-416. doi:10.1007/s10555-006-9005-3. PubMed: 16951987.
7. Leung L, Radulovich N, Zhu CQ, Organ S, Bandarchi B, et al. (2012) Lipocalin2 promotes invasion, tumorigenicity and gemcitabine resistance in pancreatic ductal adenocarcinoma. PLOS ONE 7: e46677. doi:10.1371/journal.pone.0046677. PubMed: 23056397.
8. Nieman KM, Kenny HA, Penicka CV, Ladanyi A, Buell-Gutbrod R, et al. (2011) Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Nat Med 17: 1498-1503. doi:10.1038/nm.2492. PubMed: 22037646.
9. Dalamaga M, Diakopoulos KN, Mantzoros CS, (2012) The role of adiponectin in cancer: a review of current evidence. Endocr Rev 33: 547-594. doi:10.1210/er.2011-1015. PubMed: 22547160.
10. Ho GY, Wang T, Gunter MJ, Strickler HD, Cushman M, et al. (2012) Adipokines linking obesity with colorectal cancer risk in postmenopausal women. Cancer Res 72: 3029-3037. doi:10.1158/0008-5472.CAN-11-2771. PubMed: 22511581.
11. Heikkilä K, Ebrahim S, Lawlor DA, (2007) A systematic review of the association between circulating concentrations of C reactive protein and cancer. J Epidemiol Community Health 61: 824-833. doi:10.1136/jech.2006.051292. PubMed: 17699539.
12. Chan AT, Ogino S, Giovannucci EL, Fuchs CS, (2011) Inflammatory markers are associated with risk of colorectal cancer and chemopreventive response to anti-inflammatory drugs. Gastroenterology 140: 799-808, quiz: 10.1053/j.gastro.2010.11.041. PubMed: 21115010.
13. Hancke K, Grubeck D, Hauser N, Kreienberg R, Weiss JM, (2010) Adipocyte fatty acid-binding protein as a novel prognostic factor in obese breast cancer patients. Breast Cancer Res Treat 119: 367-367. doi:10.1007/s10549-009-0577-9. PubMed: 19842034.
14. WHO. expert consultantion (2004) Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet 363: 157-163.
15. Pacific Asia Cohort Studies Collaboration (2007) The burden of overweight and obesity in Pacific:The Asia Publishing House region. Obes Rev 8: 191-196.
16. Janus ED, Watt NM, Lam KS, Cockram CS, Siu ST, et al. (2000) The prevalence of diabetes, association with cardiovascular risk factors and implications of diagnostic criteria (ADA 1997 and WHO 1998) in a 1996 community-based population study in Hong Kong Chinese. Hong Kong Cardiovascular Risk Factor Steering Committee American Diabetes Association. Diabet Med 17: 741-745.
17. Cheung BM, Wat NM, Man YB, Tam S, Thomas GN, et al. (2007) Development of diabetes in Chinese with the metabolic syndrome: a 6-year prospective study. Diabetes Care 30: 1430-1436. doi:10.2337/dc06-1820. PubMed: 17337491.
18. Chow WS, Cheung BM, Tso AW, Xu A, Wat NM, et al. (2007) Hypoadiponectinemia as a predictor for the development of hypertension: a 5-year prospective study. Hypertension 49: 1455-1461. doi:10.1161/HYPERTENSIONAHA.107.086835. PubMed: 17452504.
19. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, et al. (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-419. doi:10.1007/BF00280883. PubMed: 3899825.
20. Wang Y, Lam KS, Kraegen EW, Sweeney G, Zhang J, et al. (2007) Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans. Clin Chem 53: 34-41. PubMed: 17040956.
21. Jones DW, Hall JE, (2004) Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure and evidence from new hypertension trials. Hypertension 43: 1-3. doi:10.1161/01.HYP.0000105111.06482.7E. PubMed: 14676222.
22. Alberti KG, Zimmet P, Shaw J, (2005) The metabolic syndrome--a new worldwide definition. Lancet 366: 1059-1062. doi:10.1016/S0140-6736(05)67402-8. PubMed: 16182882.
23. Folkerd EJ, Dowsett M, (2010) Influence of sex hormones on cancer progression. J Clin Oncol 28: 4038-4044. doi:10.1200/JCO.2009.27.4290. PubMed: 20644089.
24. McMillan DC, Sattar N, McArdle CS, (2006) ABC of obesity. Obesity and cancer. BMJ 333: 1109-1111. doi:10.1136/bmj.39042.565035.BE1. PubMed: 17124223.
25. Giovannucci E, Michaud D, (2007) The role of obesity and related metabolic disturbances in cancers of the colon, prostate, and pancreas. Gastroenterology 132: 2208-2225. doi:10.1053/j.gastro.2007.03.050. PubMed: 17498513.
26. Parr CL, Batty GD, Lam TH, Barzi F, Fang X, et al. (2010) Body-mass index and cancer mortality in the Asia-Pacific Cohort Studies Collaboration: pooled analyses of 424,519 participants. Lancet Oncol 11: 741-752. doi:10.1016/S1470-2045(10)70141-8. PubMed: 20594911.
27. Jemal A, Center MM, DeSantis C, Ward EM, (2010) Global patterns of cancer incidence and mortality rates and trends. Cancer Epidemiol Biomarkers Prev 19: 1893-1907. doi:10.1158/1055-9965.EPI-10-0437. PubMed: 20647400.
28. Fontana L, Eagon JC, Trujillo ME, Scherer PE, Klein S, (2007) Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes 56: 1010-1013. doi:10.2337/db06-1656. PubMed: 17287468.
29. Hsing AW, Deng J, Sesterhenn IA, Mostofi FK, Stanczyk FZ, et al. (2000) Body size and prostate cancer: a population-based case-control study in China. Cancer Epidemiol Biomarkers Prev 9: 1335-1341. PubMed: 11142419.
30. Ansary-Moghaddam A, Huxley R, Barzi F, Lawes C, Ohkubo T, et al. (2006) The effect of modifiable risk factors on pancreatic cancer mortality in populations of the Asia-Pacific region. Cancer Epidemiol Biomarkers Prev 15: 2435-2440. doi:10.1158/1055-9965.EPI-06-0368. PubMed: 17164367.
31. Huang SP, Wu MS, Shun CT, Wang HP, Lin MT, et al. (2004) Interleukin-6 increases vascular endothelial growth factor and angiogenesis in gastric carcinoma. J Biomed Sci 11: 517-527. doi:10.1007/BF02256101. PubMed: 15153787.
32. Tworoger SS, Mantzoros C, Hankinson SE, (2007) Relationship of plasma adiponectin with sex hormone and insulin-like growth factor levels. Obesity (Silver Spring) 15: 2217-2224. doi:10.1038/oby.2007.263. PubMed: 17890489.
33. Kishimoto T, (2010) IL-6: from its discovery to clinical applications. Int Immunol 22: 347-352. doi:10.1093/intimm/dxq030. PubMed: 20410258.
34. Locksley RM, Killeen N, Lenardo MJ, (2001) The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104: 487-501. doi:10.1016/S0092-8674(01)00237-9. PubMed: 11239407.
35. Grivennikov S, Karin E, Terzic J, Mucida D, Yu GY, et al. (2009) IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell 15: 103-113. doi:10.1016/j.ccr.2009.01.001. PubMed: 19185845.
36. Lin WW, Karin M, (2007) A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 117: 1175-1183. doi:10.1172/JCI31537. PubMed: 17476347.
37. Ridker PM, Rifai N, Stampfer MJ, Hennekens CH, (2000) Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men. Circulation 101: 1767-1772. doi:10.1161/01.CIR.101.15.1767. PubMed: 10769275.
38. Fernandez-Real JM, Broch M, Vendrell J, Ricart W, (2003) Smoking, fat mass and activation of the tumor necrosis factor-alpha pathway. Int J Obes Relat Metab Disord 27: 1552-1556. doi:10.1038/sj.ijo.0802472. PubMed: 12975637.
39. Grossmann ME, Nkhata KJ, Mizuno NK, Ray A, Cleary MP, (2008) Effects of adiponectin on breast cancer cell growth and signaling. Br J Cancer 98: 370-379. doi:10.1038/sj.bjc.6604166. PubMed: 18182989.
40. Baillargeon J, Platz EA, Rose DP, Pollock BH, Ankerst DP, et al. (2006) Obesity, adipokines, and prostate cancer in a prospective population-based study. Cancer Epidemiol Biomarkers Prev 15: 1331-1335. doi:10.1158/1055-9965.EPI-06-0082. PubMed: 16835332.
41. Petridou ET, Mitsiades N, Gialamas S, Angelopoulos M, Skalkidou A, et al. (2007) Circulating adiponectin levels and expression of adiponectin receptors in relation to lung cancer: two case-control studies. Oncology 73: 261-269. doi:10.1159/000127424. PubMed: 18424891.
42. Straub RH, (2007) The complex role of estrogens in inflammation. Endocr Rev 28: 521-574. doi:10.1210/er.2007-0001. PubMed: 17640948.