Regional and Epi- to Endocardial Differences in Transmural Angles of Left Ventricular Cardiomyocytes Measured in Ex Vivo Pig Hearts: Functional Implications

Anatomical Record

Volumn 296, Issue 11, 2013, Pages 1724-1734

  Smerup, Morten ^a   Agger, Peter ^a   Nielsen, Eva Amalie ^a   Ringgaard, Steffen ^a   Pedersen, Michael ^a   Niederer, Peter ^b   Anderson, Robert H ^c   Lunkenheimer, Paul P ^d  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b ETH ZURICH   (Switzerland)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Cardiomyocytes; Diffusion tensor magnetic resonance; Left ventricle; Myocardial architecture; Myocardium

Indexed keywords

POLYMER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR PARAMETERS; COMPARATIVE STUDY; CONTROLLED STUDY; DIFFUSION TENSOR IMAGING; ENDOCARDIUM; EPICARDIUM; EX VIVO STUDY; FEMALE; HEART FUNCTION; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE WALL; HEART MUSCLE; NONHUMAN; PRIORITY JOURNAL; TRANSMURAL ANGULATION;

CARDIOMYOCYTES; DIFFUSION TENSOR MAGNETIC RESONANCE; LEFT VENTRICLE; MYOCARDIAL ARCHITECTURE; MYOCARDIUM;

ANIMALS; DIFFUSION TENSOR IMAGING; ENDOCARDIUM; FEMALE; HEART VENTRICLES; MODELS, ANIMAL; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PERICARDIUM; SWINE; VENTRICULAR FUNCTION, LEFT;

EID: 84886239447     PISSN: 19328486     EISSN: 19328494     Source Type: Journal    
DOI: 10.1002/ar.22787     Document Type: Article

References (37)

1. Anderson RH, Ho SY, Redmann K, Sanchez-Quintana D, Lunkenheimer PP. 2005. The anatomical arrangement of the myocardial cells making up the ventricular mass. EurJ Cardiothorac Surg 28:517-525.
2. Arts T, Meerbaum S, Reneman RS, Corday E. 1984. Torsion of the left ventricle during the ejection phase in the intact dog. Cardiovasc Res 18:183-193.
3. Arts T, Reneman RS. 1980. Measurement of deformation of canine epicardium in vivo during cardiac cycle. Am J Physiol 239:H432-H437.
4. Arts T, Reneman RS, Veenstra PC. 1979. A model of the mechanics of the left ventricle. Ann Biomed Eng 7:299-318.
5. Arts T, Veenstra PC, Reneman RS. 1982. Epicardial deformation and left ventricular wall mechanisms during ejection in the dog. Am J Physiol 243:H379-H390.
6. Bogaert J, Rademakers FE. 2001. Regional nonuniformity of normal adult human left ventricle. AmJ Physiol Heart Circ Physiol 280:H610-H620.
7. Bovendeerd PH, Kroon W, Delhaas T. 2009. Determinants of left ventricular shear strain. Am J Physiol Heart Circ Physiol 297:H1058-H1068.
8. Brachet JL. 1813. Sur la cause du mouvement de dilatation du coeur. Imprimerie de Didot Jeune.
9. Chadwick RS. 1982. Mechanics of the left ventricle. Biophys J 39:279-288.
10. Dorri F, Niederer PF, Lunkenheimer PP. 2006. A finite element model of the human left ventricular systole. Comp Methods Biomech Biomed Eng 9:319-341.
11. Frank O. 1901. Isometrie und Isotonie des Herzmuskels. Z Biol 41:14-34.
12. Gallagher KP, Osakada G, Matsuzaki M, Miller M, Kemper WS, Ross J, Jr. 1985. Nonuniformity of inner and outer systolic wall thickening in conscious dogs. AmJ Physiol 249:H241-H248.
13. Geerts L, Bovendeerd P, Nicolay K, Arts T. 2002. Characterization of the normal cardiac myofiber field in goat measured with MR-diffusion tensor imaging. Am J Physiol Heart Circ Physiol 283:H139-H145.
14. Greenbaum RA, Ho SY, Gibson DG, Becker AE, Anderson RH. 1981. Left ventricular fibre architecture in man. Br Heart J 45:248-263.
15. Halle W, Wollenberger A. 1970. Differentiation and behavior of isolated embryonic and neonatal heart cells in a chemically defined medium. AmJ Cardiol 25:292-299.
16. Hansen DE, Daughters GT, II, Alderman EL, Stinson EB, Baldwin JC, Miller DC. 1987. Effect of acute human cardiac allograft rejection on left ventricular systolic torsion and diastolic recoil measured by intramyocardial markers. Circulation 76:998-1008.
17. Hsu EW, Muzikant AL, Matulevicius SA, Penland RC, Henriquez CS. 1998. Magnetic resonance myocardial fiber-orientation mapping with direct histological correlation. Am J Physiol 274:H1627-H1634.
18. Ingels NB, Jr, Hansen DE, Daughters GT, II, Stinson EB, Alderman EL, Miller DC. 1989. Relation between longitudinal, circumferential, and oblique shortening and torsional deformation in the left ventricle of the transplanted human heart. Circ Res 64:915-927.
19. Julian FJ, Sollins MR. 1975. Sarcomere length-tension relations in living rat papillary muscle. Circ Res 37:299-308.
20. Krueger JW, Pollack GH. 1975. Myocardial sarcomere dynamics during isometric contraction. J Physiol 251:627-643.
21. Lehto H, Tirri R. 1980. Characterization of contractions in mechanically disaggregated myocardial cells from the rat. Acta Physiol Scand 110:385-389.
22. Lombaert H, Peyrat JM, Croisille P, Rapacchi S, Fanton L, Cheriet F, Clarysse P, Magnin I, Delingette H, Ayache N. 2012. Human atlas of the cardiac fiber architecture: study on a healthy population. IEEE Trans Med Imaging 31:1436-1447.
23. Lunkenheimer PP, Redmann K, Florek J, Fassnacht U, Cryer CW, Wubbeling F, Niederer P, Anderson RH. 2004. The forces generated within the musculature of the left ventricular wall. Heart 90:200-207.
24. Lunkenheimer PP, Redmann K, Kling N, Jiang X, Rothaus K, Cryer CW, Wubbeling F, Niederer P, Heitz PU, Ho SY, Anderson RH. 2006. Three-dimensional architecture of the left ventricular myocardium. Anat Rec A: Discov Mol Cell Evol Biol 288:565-578.
25. Nielsen E, Smerup M, Agger P, Frandsen J, Ringgard S, Pedersen M, Vestergaard P, Nyengaard JR, Andersen JB, Lunkenheimer PP, Anderson RH, Hjortdal V. 2009. Normal right ventricular three-dimensional architecture, as assessed with diffusion tensor magnetic resonance imaging, is preserved during experimentally induced right ventricular hypertrophy. Anat Rec 292:640-651.
26. Pettigrew JB. 1864. On the arrangement of the muscular fibres in the ventricles of the vertebrate, with physiological remarks. Philos Trans 154:445-500.
27. Rijcken J, Bovendeerd PH, Schoofs AJ, van Campen DH, Arts T. 1999. Optimization of cardiac fiber orientation for homogeneous fiber strain during ejection. Ann Biomed Eng 27:289-297.
28. Rodriguez EK, Hunter WC, Royce MJ, Leppo MK, Douglas AS, Weisman HF. 1992. A method to reconstruct myocardial sarcomere lengths and orientations at transmural sites in beating canine hearts. Am J Physiol 263:H293-H306.
29. Sabbah HN, Marzilli M, Stein PD. 1981. The relative role of subendocardium and subepicardium in left ventricular mechanics. Am J Physiol 240:H920-H926.
30. Schmid P, Lunkenheimer PP, Redmann K, Rothaus K, Jiang X, Cryer CW, Jaermann T, Niederer P, Boesiger P, Anderson RH. 2007. Statistical analysis of the angle of intrusion of porcine ventricular myocytes from epicardium to endocardium using diffusion tensor magnetic resonance imaging. Anat Rec 290:1413-1423.
31. Scollan DF, Holmes A, Winslow R, Forder J. 1998. Histological validation of myocardial microstructure obtained from diffusion tensor magnetic resonance imaging. Am J Physiol 275:H2308-H2318.
32. Smerup M, Nielsen E, Agger P, Frandsen J, Vestergaard-Poulsen P, Andersen J, Nyengaard J, Pedersen M, Ringgaard S, Hjortdal V, Lunkenheimer PP, Anderson RH. 2009. The three-dimensional arrangement of the myocytes aggregated together within the mammalian ventricular myocardium. Anat Rec 292:1-11.
33. Smerup M, Partridge J, Agger P, Ringgaard S, Pedersen M, Petersen S, Hasenkam JM, Niederer P, Lunkenheimer PP, Anderson RH. 2013. A mathematical model of the mechanical link between shortening of the cardiomyocytes and systolic deformation of the left ventricular myocardium. Technol Health Care 21:63-79.
34. Stevens C, Hunter PJ. 2003. Sarcomere length changes in a 3D mathematical model of the pig ventricles. Prog Biophys Mol Biol 82:229-241.
35. Streeter DD, Jr, Hanna WT. 1973. Engineering mechanics for successive states in canine left ventricular myocardium. II. Fiber angle and sarcomere length. Circ Res 33:656-664.
36. Streeter DD, Jr, Spotnitz HM, Patel DP, Ross J, Jr, Sonnenblick EH. 1969. Fiber orientation in the canine left ventricle during diastole and systole. Circ Res 24:339-347.
37. Streeter DD, Jr, Basset, D. L. 1966. An engineering analysis of myocardial fiber orientation in pig's left ventricle in systole. Anat Rec 155:503.