Role of osteopontin in modulation of hydroxyapatite formation

Calcified Tissue International

Volumn 93, Issue 4, 2013, Pages 348-354

  Hunter, Graeme K ^a  

^a WESTERN UNIVERSITY   (Canada)

Author keywords

Biomineralization; Ectopic calcification; Matrix protein

Indexed keywords

CALCIUM ION; CALCIUM OXALATE; HYDROXYAPATITE; OSTEOPONTIN;

ADSORPTION; AMINO ACID SEQUENCE; ARTICLE; ATHEROSCLEROTIC PLAQUE; BIOMINERALIZATION; BONE GROWTH; BONE MINERAL; BONE MINERALIZATION; CHEMICAL BOND; CRYSTAL STRUCTURE; CRYSTALLIZATION; HUMAN; NEPHROLITHIASIS; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; SMOOTH MUSCLE FIBER; SOFT TISSUE CALCIFICATION; UPREGULATION; VASCULAR SMOOTH MUSCLE;

ADSORPTION; AMINO ACID MOTIFS; ANIMALS; BONE AND BONES; CALCIFICATION, PHYSIOLOGIC; CALCIUM; CRYSTALLIZATION; DURAPATITE; HUMANS; IONS; MICE; OSTEOBLASTS; OSTEOPONTIN; PHOSPHORYLATION; PLAQUE, ATHEROSCLEROTIC; PROTEIN STRUCTURE, TERTIARY; RATS; SIALOGLYCOPROTEINS;

EID: 84886100690     PISSN: 0171967X     EISSN: 14320827     Source Type: Journal    
DOI: 10.1007/s00223-013-9698-6     Document Type: Article

References (67)

1. Herring GM, Kent PW (1963) Some studies on mucosubstances of bovine cortical bone. Biochemistry 89:405-414
2. Franzén A, Heinegård D (1985) Isolation and characterization of two sialoproteins present only in bone calcified matrix. Biochemistry 232:715-724 (Pubitemid 16207308)
3. Prince CW, Oosawa T, Butler WT, Tomana M, Bhown AS, Bhown M, Schrohenloher RE (1987) Isolation, characterization, and biosynthesis of phosphorylated glycoprotein from rat bone. J Biol Chem 262:2900-2907
4. Oldberg A, Franzén A, Heinegård D (1986) Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence. Proc Natl Acad Sci USA 83:8819-8823 (Pubitemid 17223492)
5. Sørensen ES, Højrup P, Petersen TE (1995) Posttranslational modifications of bovine osteopontin: identification of twenty-eight phosphorylation and three O-glycosylation sites. Protein Sci 4:2040-2049
6. Keykhosravani M, Doherty-Kirby A, Zhang C, Brewer D, Goldberg HA, Hunter GK, Lajoie G (2005) Comprehensive identification of post-translational modifications of rat bone osteopontin by mass spectrometry. Biochemistry 44:6990-7003 (Pubitemid 40632417)
7. Christensen B, Petersen TE, Sorensen ES (2008) Post-translational modification and proteolytic processing of urinary osteopontin. Biochem J 411:53-61 (Pubitemid 351482346)
8. Masuda K, Takahashi N, Tsukamoto Y, Honma H, Kohri K (2000) N-Glycan structure of an osteopontin from human bone. Biochem Biophys Res Commun 268:814-817 (Pubitemid 30150874)
9. Kaartinen MT, Pirhonen A, Linnala-Kankkunen A, Mäenpää PH (1999) Cross-linking of osteopontin by tissue transglutaminase increases its collagen binding properties. J Biol Chem 274:1729-1735 (Pubitemid 29057998)
10. Gericke A, Qin C, Spevak L, Fujimoto Y, Butler WT, Sorensen ES, Boskey AL (2005) Importance of phosphorylation for osteopontin regulation of biomineralization. Calcif Tissue Int 77:45-54 (Pubitemid 41504172)
11. Fisher LW, Torchia DA, Fohr B, Young MF, Fedarko NS (2001) Flexible structures of SIBLING proteins, bone sialoprotein and osteopontin. Biochem Biophys Res Commun 280:460-465 (Pubitemid 32912812)
12. Azzopardi PV, O'Young J, Lajoie G, Karttunen M, Goldberg HA, Hunter GK (2010) Roles of charge and conformation in protein-crystal interactions. PLoS ONE 5:e9330
13. Dyson HJ, Wright PE (2005) Intrinsically unstructured proteins and their functions. Nat Rev Mol Cell Biol 6:197-208 (Pubitemid 40314921)
14. Zhang Q, Domenicucci C, Goldberg HA, Wrana JL, Sodek J (1990) Characterization of fetal porcine bone sialoproteins, secreted phosphoprotein I (SPPI, osteopontin), bone sialoprotein, and a 23-kDa glycoprotein. J Biol Chem 265:7583-7589
15. Barros NM, Hoac B, Neves RL, Addison WN, Assis DM, Murshed M, Carmona AK, McKee MD (2012) Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X-linked hypophosphatemia. J Bone Miner Res. doi: 10.1002/jbmr.1766
16. Simmer JP, Fincham AG (1995) Molecular mechanisms of dental enamel formation. Crit Rev Oral Biol Med 6:84-108
17. Weiner S, Price PA (1986) Disaggregation of bone into crystals. Calcif Tissue Int 39:365-375
18. Nomura S, Wills AJ, Edwards DR, Heath JK, Hogan BLM (1988) Developmental expression of 2ar (osteopontin) and SPARC (osteonectin) RNA as revealed by in situ hybridization. J Cell Biol 106:441-450 (Pubitemid 18052192)
19. Kohri K, Suzuki Y, Yoshida K, Yamamoto K, Amasaki N, Yamate T, Umekawa T, Iguchi M, Sinohara H, Kurita T (1992) Molecular cloning and sequencing of cDNA encoding urinary stone protein, which is identical to osteopontin. Biochem Biophys Res Commun 184:859-864
20. Giachelli CM, Bae N, Almeida M, Denhardt DT, Alpers CE, Schwartz SM (1993) Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques. J Clin Invest 92:1686-1696 (Pubitemid 23304531)
21. Brown LF, Berse B, Van De Water L, Papadopoulos-Sergious A, Perruzzi CA, Manseau EJ, Dvorak HF, Senger DR (1992) Expression and distribution of osteopontin in human tissues: widespread association with luminal epithelial surfaces. Mol Biol Cell 3:1169-1180 (Pubitemid 23088966)
22. Senger DR, Perruzzi CA, Papadopoulos A, Tenen DG (1989) Purification of human milk protein closely similar to tumor-secreted phosphoproteins and osteopontin. Biochim Biophys Acta 996:43-48 (Pubitemid 19152726)
23. Min W, Shiraga H, Chalko C, Goldfarb S, Krishna GG, Hoyer JR (1998) Quantitative studies of human urinary excretion of uropontin. Kidney Int 53:189-193 (Pubitemid 28066920)
24. Chen J, McKee MD, Nanci A, Sodek J (1994) Bone sialoprotein mRNA expression and ultrastructural localization in fetal porcine calvarial bone: comparisons with osteopontin. Histochem J 26:67-78 (Pubitemid 24049328)
25. McKee MD, Nanci A (1995) Postembedding colloidal-gold immunocytochemistry of noncollogenous extracellular matrix proteins in mineralized tissues. Microsc Res Tech 31:44-62
26. Hirota S, Asada H, Kohri K, Tsukamoto Y, Ito A, Yoshikawa K, Xu Z, Nomura S, Kitamura Y (1995) Possible role of osteopontin in deposition of calcium phosphate in human pilomatricomas. J Invest Dermatol 105:138-142
27. Kohri K, Nomura S, Kitamura Y, Nagata T, Yoshioka K, Iguchi M, Yamate T, Umekawa T, Suzuki Y, Sinohara H, Kurita T (1993) Structure and expression of the mRNA encoding urinary stone protein (osteopontin). J Biol Chem 268:15180-15184 (Pubitemid 23206672)
28. Beck GR, Zerle B, Moran E (2000) Phosphate is a specific signal for induction of osteopontin gene expression. Proc Natl Acad Sci USA 97:8352-8357 (Pubitemid 30639676)
29. Chen NX, O'Neill KD, Duan D, Moe SM (2002) Phosphorus and uremic serum up-regulate osteopontin expression in vascular smooth muscle cells. Kidney Int 62:1724-1731 (Pubitemid 35286280)
30. Chiba S, Okamoto H, Kon S, Kimura C, Murakami M, Inobe M, Matsui Y, Sugawara T, Shimizu T, Uede T, Kitabatake A (2002) Development of atherosclerosis in osteopontin transgenic mice. Heart Vessels 16:111-117 (Pubitemid 34464396)
31. Hamamoto S, Nomura S, Yasui T, Okada A, Hirose M, Shimizu H, Itoh Y, Tozawa K, Kohri K (2010) Effects of impaired functional domains of osteopontin on renal crystal formation: analyses of OPN transgenic and OPN knockout mice. J Bone Miner Res 25:2436-2447
32. Rittling SR, Matsumoto HN, McKee MD, Nanci A, An XR, Novick KE, Kowalski AJ, Noda M, Denhardt DT (1998) Mice lacking osteopontin show normal development and bone structure but display altered osteoclast formation in vitro. J Bone Miner Res 13:1101-1111 (Pubitemid 28311778)
33. Boskey AL, Spevak L, Paschalis E, Doty SB, McKee MD (2002) Osteopontin deficiency increases mineral content and mineral crystallinity in mouse bone. Calcif Tissue Int 71:145-154 (Pubitemid 36935480)
34. -/- mice. J Bone Miner Res 21:1377-1386 (Pubitemid 44300044)
35. McKee MD, Nanci A (1996) Osteopontin at mineralized tissue interfaces in bone, teeth, and osseointegrated implants: ultrastructural distribution and implications for mineralized tissue formation, turnover, and repair. Microsc Res Tech 33:141-164 (Pubitemid 26021996)
36. Liaw L, Birk DE, Ballas CB, Whitsitt JS, Davidson JM, Hogan BLM (1998) Altered wound healing in mice lacking a functional osteopontin gene (spp 1). J Clin Invest 101:1468-1478 (Pubitemid 28166845)
37. Wesson JA, Johnson RJ, Mazzali M, Beshensky AM, Stietz S, Giachelli C, Liaw L, Alpers CE, Couser WG, Kleinman JG, Hughes J (2003) Osteopontin is a critical inhibitor of calcium oxalate crystal formation and retention in renal tubules. J Am Soc Nephrol 14:139-147 (Pubitemid 36026305)
38. Steitz SA, Speer MY, McKee MD, Liaw L, Almeida M, Yang H, Giachelli CM (2002) Osteopontin inhibits mineral deposition and promotes regression of ectopic calcification. Am J Pathol 161:2035-2046 (Pubitemid 35434850)
39. Mo L, Liaw L, Evan AP, Sommer AJ, Lieske JC, Wu XR (2007) Renal calcinosis and stone formation in mice lacking osteopontin, Tamm-Horsfall protein, or both. Am J Physiol Renal Physiol 293:F1935-F1943 (Pubitemid 350179618)
40. Speer MY, McKee MD, Guldberg RE, Liaw L, Yang HY, Tung E, Karsenty G, Giachelli CM (2002) Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein-deficient mice: evidence for osteopontin as an inducible inhibitor of vascular calcification in vivo. J Exp Med 196:1047-1055 (Pubitemid 35231763)
41. Schafer C, Heiss A, Schwarz A, Westenfeld R, Ketteler M, Floege J, Muller-Esterl W, Schinke T, Jahnen-Dechent W (2003) The serum protein alpha 2-Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification. J Clin Invest 112:357-366 (Pubitemid 38063764)
42. Boskey AL, Maresca M, Ullrich W, Doty SB, Butler WT, Prince CW (1993) Osteopontin-hydroxyapatite interactions in vitro. Inhibition of hydroxyapatite formation and growth in a gelatin-gel. Bone Miner 22:147-159 (Pubitemid 23272798)
43. Goldberg HA, Warner KJ, Li MC, Hunter GK (2001) Binding of bone sialoprotein, osteopontin and synthetic polypeptides to hydroxyapatite. Connect Tissue Res 42:25-37 (Pubitemid 32894349)
44. Silverman LD, Saadia M, Ishal JS, Tishbi N, Leiderman E, Kuyunov I, Recca B, Reitblat C, Viswanathan R (2010) Hydroxyapatite growth inhibition by osteopontin hexapeptide sequences. Langmuir 26:9899-9904
45. Addison WN, Masica DL, Gray JJ, McKee MD (2010) Phosphorylation-dependent inhibition of mineralization by osteopontin ASARM peptides is regulated by PHEX cleavage. J Bone Miner Res 25:695-705
46. Fujisawa R, Kuboki Y (1991) Preferential adsorption of dentin and bone acidic proteins on the (100) face of hydroxyapatite crystals. Biochim Biophys Acta 1075:56-60
47. Hoang QQ, Sicheri F, Howard AJ, Yang DS (2003) Bone recognition mechanism of porcine osteocalcin from crystal structure. Nature 425:977-980 (Pubitemid 37376930)
48. Huq NL, Cross KJ, Reynolds EC (2000) Molecular modelling of a multiphosphorylated sequence motif bound to hydroxyapatite surfaces. J Mol Model 6:35-47
49. Grohe B, O'Young J, Ionescu A, Lajoie G, Rogers KA, Karttunen M, Goldberg HA, Hunter GK (2007) Control of calcium oxalate crystal growth by face-specific adsorption of an osteopontin phosphopeptide. J Am Chem Soc 129:14946-14951 (Pubitemid 350230716)
50. Addison WN, Azari F, Sorensen ES, Kaartinen MT, McKee MD (2007) Pyrophosphate inhibits mineralization of osteoblast cultures by binding to mineral, up-regulating osteopontin, and inhibiting alkaline phosphatase activity. J Biol Chem 282:15872-15883 (Pubitemid 47093287)
51. Harding JH, Duffy DM, Sushko ML, Rodger PM, Quigley D, Elliott JA (2008) Computational techniques at the organic-inorganic interface in biomineralization. Chem Rev 108:4823-4854
52. O'Young J, Liao YY, Xiao YZ, Jalkanen J, Lajoie G, Karttunen M, Goldberg HA, Hunter GK (2011) Matrix Gla protein inhibits ectopic calcification by a direct interaction with hydroxyapatite crystals. J Am Chem Soc 133:18406-18412
53. Wada T, McKee MD, Steitz S, Giachelli CM (1999) Calcification of vascular smooth muscle cell cultures: inhibition by osteopontin. Circ Res 84:166-178 (Pubitemid 29070112)
54. Li S, Wang L (2012) Phosphorylated osteopontin peptides inhibit crystallization by resisting the aggregation of calcium phosphate nanoparticles. Cryst Eng Comm 14:8037-8043
55. Hunter GK, Kyle CL, Goldberg HA (1994) Modulation of crystal formation by bone phosphoproteins: structural specificity of the osteopontin-mediated inhibition of hydroxyapatite formation. Biochem J 300:723-728 (Pubitemid 24180586)
56. Hunter GK, Hauschka PV, Poole AR, Rosenberg LC, Goldberg HA (1996) Nucleation and inhibition of hydroxyapatite formation by mineralized tissue proteins. Biochem J 317:59-64 (Pubitemid 26238329)
57. Boskey AL, Christensen B, Taleb H, Sorensen ES (2012) Post-translational modification of osteopontin: effects on in vitro hydroxyapatite formation and growth. Biochem Biophys Res Commun 419:333-338
58. Tomson MB, Nancollas GH (1978) Mineralization kinetics: a constant composition approach. Science 200:1059-1060 (Pubitemid 8346925)
59. Beshensky AM, Wesson JA, Worcester EM, Sorokina EJ, Snyder CJ, Kleinman JG (2001) Effects of urinary macromolecules on hydroxyapatite crystal formation. J Am Soc Nephrol 12:2108-2116 (Pubitemid 32880347)
60. Kumura H, Minato N, Shimazaki K (2006) Inhibitory activity of bovine milk osteopontin and its fragments on the formation of calcium phosphate precipitates. J Dairy Res 73:449-453 (Pubitemid 44624074)
61. Linde A, Lussi A, Crenshaw MA (1989) Mineral induction by immobilized polyanionic proteins. Calcif Tissue Int 44:286-295 (Pubitemid 19114722)
62. Speer MY, Chien YC, Quan M, Yang HY, Vali H, McKee MD, Giachelli CM (2005) Smooth muscle cells deficient in osteopontin have enhanced susceptibility to calcification in vitro. Cardiovasc Res 66:324-333 (Pubitemid 40471047)
63. Jono S, Peinado C, Giachelli CM (2000) Phosphorylation of osteopontin is required for inhibition of vascular smooth muscle cell calcification. J Biol Chem 275:20197-20203 (Pubitemid 30441631)
64. Evans JS (2003) "Apples" and "oranges": comparing the structural aspects of biomineral- and ice-interaction proteins. Curr Opin Colloid Interface Sci 8:48-54 (Pubitemid 36740823)
65. Hunter GK, O'Young J, Grohe B, Karttunen M, Goldberg HA (2010) The flexible polyelectrolyte hypothesis of protein-biomineral interaction. Langmuir 26:18639-18646
66. Vekilov PG (2007) What determines the rate of growth of crystals from solution? Cryst Growth Des 7:2796-2810
67. Weaver ML, Qiu SR, Hoyer JR, Casey WH, Nancollas GH, De Yoreo JJ (2009) Surface aggregation of urinary proteins and aspartic acid-rich peptides on the faces of calcium oxalate monohydrate investigated by in situ force microscopy. Calcif Tissue Int 84:462-473