Benefits of physical exercise on the aging brain: The role of the prefrontal cortex

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 68, Issue 11, 2013, Pages 1337-1341

  Berchicci, Marika ^a   Lucci, Giuliana ^b   Di Russo, Francesco ^a,b  

^a UNIVERSITY OF ROME FORO ITALICO   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

Author keywords

Middle aged; Movement related cortical potential; Physical exercise; Prefrontal cortex

Indexed keywords

ADOLESCENT; ADULT; AGED; AGING; ARTICLE; EXERCISE; FEMALE; HUMAN; MALE; MIDDLE AGED; MOVEMENT-RELATED CORTICAL POTENTIAL.; PHYSIOLOGY; PREFRONTAL CORTEX; REACTION TIME; VERY ELDERLY;

MIDDLE AGED; MOVEMENT-RELATED CORTICAL POTENTIAL.; PHYSICAL EXERCISE; PREFRONTAL CORTEX;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; EXERCISE; FEMALE; HUMANS; MALE; MIDDLE AGED; PREFRONTAL CORTEX; REACTION TIME;

EID: 84886053353     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glt094     Document Type: Article

References (23)

1. Heuninckx S, Wenderoth N, Swinnen SP. Systems neuroplasticity in the aging brain: recruiting additional neural resources for successful motor performance in elderly persons. J Neurosci. 2008;28:91-99.
2. Berchicci M, Lucci G, Pesce C, Spinelli D, Di Russo F. Prefrontal hyperactivity in older people during motor planning. Neuroimage. 2012;62:1750-1760.
3. Hedden T, Gabrieli JD. Insights into the ageing mind: a view from cognitive neuroscience. Nat Rev Neurosci. 2004;5:87-96.
4. Seidler RD, Bernard JA, Burutolu TB, et al. Motor control and aging: links to age-related brain structural, functional, and biochemical effects. Neurosci Biobehav Rev. 2010;34:721-733.
5. Park DC, Reuter-Lorenz P. The adaptive brain: aging and neurocognitive scaffolding. Annu Rev Psychol. 2009;60:173-196.
6. Di Pietro L. Physical activity in aging: changes in patterns and their relationship to health and function. J Geront: SERIES A 2001;56A:13-22.
7. Kramer AF, Erickson KI, Colcombe SJ. Exercise, cognition, and the aging brain. J Appl Physiol. 2006;101:1237-1242.
8. Hillman CH, Belopolsky AV, Snook EM, Kramer AF, McAuley E. Physical activity and executive control: implications for increased cognitive health during older adulthood. Res Q Exerc Sport. 2004;75:176-185.
9. Thompson PD, Buchner D, Pina IL, et al. Exercise and physical activity in the prevention and treatment of atherosclerotic cardiovascular disease: a statement from the Council on Clinical Cardiology (Subcommittee on Exercise, Rehabilitation, and Prevention) and the Council on Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity). Circulation. 2003;107:3109-3116.
10. Oldfield RC. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 1971;104:199-206.
11. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12:189-198.
12. Zimmermann P, Fimm B. Testbatterie zur Aufmerksamkeitsprüfung (TAP). Würselen: Psytest; 1992.
13. Kraft E. Cognitive function, physical activity, and aging: possible biological links and implications for multimodal interventions. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2012;19: 248-263.
14. Dietrich A. Transient hypofrontality as a mechanism for the psychological effects of exercise. Psychiatry Res. 2006;145:79-83.
15. Murugesan N, Demarest TG, Madri JA, Pachter JS. Brain regional angiogenic potential at the neurovascular unit during normal aging. Neurobiol Aging. 2012;33:1004.e1-1004.16.
16. Kramer AF, Erickson KI. Capitalizing on cortical plasticity: influence of physical activity on cognition and brain function. Trends Cogn Sci. 2007;11:342-348.
17. van Praag H, Kempermann G, Gage FH. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat Neurosci. 1999;2:266-270.
18. Kempermann G. The neurogenic reserve hypothesis: what is adult hippocampal neurogenesis good for? Trends Neurosci. 2008;31:163-169.
19. Hu S, Ying Z, Gomez-Pinilla F, Frautschy SA. Exercise can increase small heat shock proteins (sHSP) and pre-and post-synaptic proteins in the hippocampus. Brain Res. 2009;1249:191-201.
20. Coelho FG, Gobbi S, Andreatto CA, Corazza DI, Pedroso RV, Santos-Galduróz RF. Physical exercise modulates peripheral levels of brain-derived neurotrophic factor (BDNF): a systematic review of experimental studies in the elderly. Arch Gerontol Geriatr. 2013;56:10-15.
21. Voelcker-Rehage C, Godde B, Staudinger UM. Cardiovascular and coordination training differentially improve cognitive performance and neural processing in older adults. Front Hum Neurosci. 2011;5:26.
22. Colcombe SJ, Erickson KI, Scalf PE, et al. Aerobic exercise training increases brain volume in aging humans. J Gerontol A Biol Sci Med Sci. 2006;61:1166-1170.
23. Erickson KI, Voss MW, Prakash RS, et al. Exercise training increases size of hippocampus and improves memory. Proc Natl Acad Sci U S A. 2011;108:3017-3022.