Intravenous sildenafil in the management of pulmonary hypertension associated with congenital diaphragmatic hernia

European Journal of Pediatric Surgery

Volumn 25, Issue 2, 2015, Pages 171-176

  Bialkowski, Anja ^a   Moenkemeyer, Florian ^a   Patel, Neil ^a  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

Author keywords

congenital diaphragmatic hernia; intravenous sildenafil; newborn infant; phosphodiesterase 5 inhibitor; pulmonary hypertension

Indexed keywords

PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL; VASODILATOR AGENT;

BLOOD FLOW VELOCITY; BLOOD PRESSURE; COMPLICATION; CONGENITAL DIAPHRAGM HERNIA; CORONARY ARTERY BLOOD FLOW; DRUG EFFECTS; ECHOGRAPHY; FEMALE; HEART OUTPUT; HUMAN; HYPERTENSION, PULMONARY; INFANT; INTRAVENOUS DRUG ADMINISTRATION; MALE; NEWBORN; OXYGEN CONSUMPTION; PHYSIOLOGY; PULMONARY ARTERY; RETROSPECTIVE STUDY;

BLOOD FLOW VELOCITY; BLOOD PRESSURE; CARDIAC OUTPUT; CORONARY CIRCULATION; FEMALE; HERNIAS, DIAPHRAGMATIC, CONGENITAL; HUMANS; HYPERTENSION, PULMONARY; INFANT; INFANT, NEWBORN; INFUSIONS, INTRAVENOUS; MALE; OXYGEN CONSUMPTION; PHOSPHODIESTERASE 5 INHIBITORS; PULMONARY ARTERY; RETROSPECTIVE STUDIES; SILDENAFIL CITRATE; VASODILATOR AGENTS;

EID: 84886027263     PISSN: 09397248     EISSN: 1439359X     Source Type: Journal    
DOI: 10.1055/s-0033-1357757     Document Type: Article

References (23)

1. Dillon P. W., Cilley R. E., Mauger D., Zachary C., Meier A. The relationship of pulmonary artery pressure and survival in congenital diaphragmatic hernia. J Pediatr Surg: 2004; 39 3 307 312, discussion 307-312
2. Wynn J., Krishnan U., Aspelund G., et al. Outcomes of congenital diaphragmatic hernia in the modern era of management. J Pediatr: 2013; 163 1 114, e1 10.1016/j.jpeds.2012.12.036
3. Shah N., Jacob T., Exler R., et al. Inhaled nitric oxide in congenital diaphragmatic hernia. J Pediatr Surg: 1994; 29 8 1010 1014, discussion 1014-1015
4. The Neonatal Inhaled Nitric Oxide Study Group (NINOS) Inhaled nitric oxide and hypoxic respiratory failure in infants with congenital diaphragmatic hernia. Pediatrics: 1997; 99 6 838 845
5. Everest N., Armstrong R., Hunt R. Neonatal outcomes following the introduction of a time-metered nitric oxide delivery system. J Paediatr Child Health: 2012; 48 S1 A089
6. Lakshminrusimha S., Steinhorn R. H. Inodilators in nitric oxide resistant persistent pulmonary hypertension of the newborn. Pediatr Crit Care Med: 2013; 14 1 107 109
7. Shah P. S., Ohlsson A. Sildenafil for pulmonary hypertension in neonates. Cochrane Database Syst Rev: 2011; 8 CD005494
8. Baquero H., Soliz A., Neira F., Venegas M. E., Sola A. Oral sildenafil in infants with persistent pulmonary hypertension of the newborn: a pilot randomized blinded study. Pediatrics: 2006; 117 4 1077 1083
9. Steinhorn R. H., Kinsella J. P., Pierce C., et al. Intravenous sildenafil in the treatment of neonates with persistent pulmonary hypertension. J Pediatr: 2009; 155 6 841 847, e1
10. Hunter L., Richens T., Davis C., Walker G., Simpson J. H. Sildenafil use in congenital diaphragmatic hernia. Arch Dis Child Fetal Neonatal Ed: 2009; 94 6 F467
11. Keller R. L., Hamrick S. E., Kitterman J. A., Fineman J. R., Hawgood S. Treatment of rebound and chronic pulmonary hypertension with oral sildenafil in an infant with congenital diaphragmatic hernia. Pediatr Crit Care Med: 2004; 5 2 184 187
12. Noori S., Friedlich P., Wong P., Garingo A., Seri I. Cardiovascular effects of sildenafil in neonates and infants with congenital diaphragmatic hernia and pulmonary hypertension. Neonatology: 2007; 91 2 92 100
13. Skinner J. R., Stuart A. G., O'Sullivan J., Heads A., Boys R. J., Hunter S. Right heart pressure determination by Doppler in infants with tricuspid regurgitation. Arch Dis Child: 1993; 69 2 216 220
14. Phillipos E. Z., Robertson M. A., Byrne P. J. Serial assessment of ductus arteriosus hemodynamics in hyaline membrane disease. Pediatrics: 1996; 98 6 Pt 1 1149 1153
15. Tsai-Goodman B., Martin R. P., Marlow N., Skinner J. R. The repeatability of echocardiographic determination of right ventricular output in the newborn. Cardiol Young: 2001; 11 2 188 194
16. Mori K., Nakagawa R., Nii M., et al. Pulsed wave Doppler tissue echocardiography assessment of the long axis function of the right and left ventricles during the early neonatal period. Heart: 2004; 90 2 175 180
17. Negrine R. J., Chikermane A., Wright J. G., Ewer A. K. Assessment of myocardial function in neonates using tissue Doppler imaging. Arch Dis Child Fetal Neonatal Ed: 2012; 97 4 F304 F306
18. Patel N., Mills J. F., Cheung M. M. Assessment of right ventricular function using tissue Doppler imaging in infants with pulmonary hypertension. Neonatology: 2009; 96 3 193 199, discussion 200-202
19. De Luca D., Zecca E., Vento G., De Carolis M. P., Romagnoli C. Transient effect of epoprostenol and sildenafil combined with iNO for pulmonary hypertension in congenital diaphragmatic hernia. Paediatr Anaesth: 2006; 16 5 597 598
20. Filan P. M., McDougall P. N., Shekerdemian L. S. Combination pharmacotherapy for severe neonatal pulmonary hypertension. J Paediatr Child Health: 2006; 42 4 219 220
21. Children's Hospital Los Angeles. Ann & Robert H Lurie Children's Hospital of Chicago, University of California, San Francisco. Chronic Sildenafil for Severe Diaphragmatic Hernia. In: ClinicalTrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2000- [cited 2013 Aug 29]. Available from: http://clinicaltrials.gov/show/NCT00133679 NLM Identifier: NCT00133679
22. Stultz J. S., Puthoff T., Backes C. Jr, Nahata M. C. Intermittent intravenous sildenafil for pulmonary hypertension management in neonates and infants. Am J Health Syst Pharm: 2013; 70 5 407 413
23. Patel N. Use of milrinone to treat cardiac dysfunction in infants with pulmonary hypertension secondary to congenital diaphragmatic hernia: a review of six patients. Neonatology: 2012; 102 2 130 136