Intravital analysis of vascular permeability in mice using two-photon microscopy

Scientific Reports

Volumn 3, Issue , 2013, Pages

  Egawa, Gyohei ^a   Nakamizo, Satoshi ^a   Natsuaki, Yohei ^a   Doi, Hiromi ^a   Miyachi, Yoshiki ^a   Kabashima, Kenji ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRAN; FLUORESCEIN ISOTHIOCYANATE; HISTAMINE; IMMUNOGLOBULIN E;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CAPILLARY PERMEABILITY; CHEMICALLY INDUCED DISORDER; CHEMISTRY; CYTOLOGY; DRUG EFFECT; FEMALE; FLUORESCENCE MICROSCOPY; HYPERSENSITIVITY; INFLAMMATION; METABOLISM; MOUSE; PATHOLOGY; PHOTON; PHYSIOLOGY; SKIN; VASCULAR ENDOTHELIUM; VASCULARIZATION;

ANIMALS; CAPILLARY PERMEABILITY; DEXTRANS; ENDOTHELIUM, VASCULAR; FEMALE; FLUORESCEIN-5-ISOTHIOCYANATE; HISTAMINE; HYPERSENSITIVITY; IMMUNOGLOBULIN E; INFLAMMATION; MICE; MICE, INBRED BALB C; MICROSCOPY, FLUORESCENCE; PHOTONS; SKIN;

EID: 84886020193     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep01932     Document Type: Article

References (17)

1. Mehta, D. & Malik, A. B. Signaling mechanisms regulating endothelial permeability. Physiol Rev 86, 279-367 (2006).
2. Vandenbroucke, E., Mehta, D., Minshall, R. & Malik, A. B. Regulation of endothelial junctional permeability. Ann N Y Acad Sci 1123, 134-145 (2008).
3. Nagy, J. A., Benjamin, L., Zeng, H., Dvorak, A. M. & Dvorak, H. F. Vascular permeability, vascular hyperpermeability and angiogenesis. Angiogenesis 11, 109-119 (2008).
4. Albelda, S. M., Sampson, P. M., Haselton, F. R.,McNiff, J. M., Mueller, S. N. et al. Permeability characteristics of cultured endothelial cell monolayers. J Appl Physiol 64, 308-322 (1988).
5. Del Vecchio, P. J., Siflinger-Birnboim, A., Shepard, J. M., Bizios, R., Cooper, J. A. et al. Endothelial monolayer permeability to macromolecules. Fed Proc 46, 2511-2515 (1987).
6. Cooper, J. A., Del Vecchio, P. J., Minnear, F. L., Burhop, K. E., Selig, W. M. et al. Measurement of albumin permeability across endothelial monolayers in vitro. J Appl Physiol 62, 1076-1083 (1987).
7. Miles, A. A. & Miles, E. M. Vascular reactions to histamine, histamine-liberator and leukotaxine in the skin of guinea-pigs. J Physiol 118, 228-257 (1952).
8. Senger, D. R., Galli, S. J., Dvorak, A. M., Perruzzi, C. A., Harvey, V. S. et al. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 219, 983-985 (1983).
9. Cahalan, M. D., Parker, I., Wei, S. H. & Miller, M. J. Two-photon tissue imaging: seeing the immune system in a fresh light. Nat Rev Immunol 2, 872-880 (2002).
10. Egawa, G.,Honda, T., Tanizaki, H.,Doi, H.,Miyachi, Y. et al. In vivo imaging of Tcell motility in the elicitation phase of contact hypersensitivity using two-photon microscopy. J Invest Dermatol 131, 977-979 (2011).
11. Egawa, G. & Kabashima, K. Skin as a peripheral lymphoid organ: revisiting the concept of skin-Associated lymphoid tissues. J Invest Dermatol 131, 2178-2185 (2011).
12. Honda, T., Egawa, G., Grabbe, S. & Kabashima, K. Update of Immune Events in the Murine Contact Hypersensitivity Model: Toward the Understanding of Allergic Contact Dermatitis. J Invest Dermatol (2012).
13. Dahlen, S. E., Bjork, J., Hedqvist, P., Arfors, K. E., Hammarstrom, S. et al. Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response. Proc Natl Acad Sci U S A 78, 3887-3891 (1981).
14. Muller, W. A. Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response. Trends Immunol 24, 327-334 (2003).
15. Simionescu, M.,Gafencu, A.& Antohe, F. Transcytosis of plasmamacromolecules in endothelial cells: a cell biological survey. Microsc Res Tech 57, 269-288 (2002).
16. Predescu, D. & Palade, G. E. Plasmalemmal vesicles represent the large pore system of continuous microvascular endothelium. Am J Physiol 265, H725-733 (1993).
17. Hu, G., Vogel, S. M., Schwartz, D. E., Malik, A. B. & Minshall, R. D. Intercellular adhesion molecule-1-dependent neutrophil adhesion to endothelial cells induces caveolae-mediated pulmonary vascular hyperpermeability. Circ Res 102, e120-131 (2008).