Epidemiology of Staphylococcus aureus Bacteraemia at a Tertiary Children's Hospital in Cape Town, South Africa

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Naidoo, Reené ^a   Nuttall, James ^a   Whitelaw, Andrew ^a   Eley, Brian ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

CEFOTAXIME; CEFTRIAXONE; CIPROFLOXACIN; CLINDAMYCIN; CLOXACILLIN; COTRIMOXAZOLE; ERYTHROMYCIN; FUSIDIC ACID; GENTAMICIN; LINEZOLID; MOXIFLOXACIN; PENICILLIN DERIVATIVE; RIFAMPICIN; TEICOPLANIN; TIGECYCLINE; VANCOMYCIN;

ADOLESCENT; ARTICLE; BACTERIUM ISOLATE; CHILD; CLINICAL FEATURE; FEMALE; HIGH RISK POPULATION; HOSPITAL INFECTION; HUMAN; INCIDENCE; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; MALNUTRITION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS BACTEREMIA; MICROBIOLOGICAL EXAMINATION; MORTALITY; NONHUMAN; OUTCOME ASSESSMENT; RETROSPECTIVE STUDY; RISK FACTOR; SCHOOL CHILD; SOUTH AFRICA; STAPHYLOCOCCAL BACTEREMIA; TERTIARY HEALTH CARE; TREATMENT DURATION; BACTEREMIA; CLINICAL TRIAL; COMPARATIVE STUDY; CROSS INFECTION; INFANT; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIOLOGY; PRESCHOOL CHILD; STAPHYLOCOCCAL INFECTIONS; TERTIARY CARE CENTER;

ADOLESCENT; BACTEREMIA; CHILD; CHILD, PRESCHOOL; CROSS INFECTION; FEMALE; HUMANS; INFANT; MALE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; RETROSPECTIVE STUDIES; SOUTH AFRICA; STAPHYLOCOCCAL INFECTIONS; TERTIARY CARE CENTERS;

EID: 84885972486     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078396     Document Type: Article

References (29)

1. Cotton MF, Burger PJ, Bodenstein WJM, (1992) Bacteraemia in children in the south-western Cape - A hospital-based survey. S Afr Med J 81: 87-90. PubMed: 1733031.
2. Cotton MF, Wasserman E, Smit J, Whitelaw A, Zar HJ, (2008) High incidence of antimicrobial resistant organisms including extended spectrum beta-lactamase producing Enterobacteriaceae and methicillin-resistant Staphylococcus aureus in nasopharyngeal and blood isolates of HIV-infected children from Cape Town. BMC Infect Dis 8: 40. doi:10.1186/1471-2334-8-40. PubMed: 18380900.
3. Jaspan HB, Huang LC, Cotton MF, Whitelaw A, Myer L, (2008) Bacterial disease and antimicrobial susceptibility patterns in HIV-infected, hospitalized children: a retrospective study. PLOS ONE 3: e3260. doi:10.1371/journal.pone.0003260. PubMed: 18813340.
4. Le Roux DM, Cotton MF, Le Roux SM, Whitelaw A, Lombard CJ, et al. (2011) Bacteremia in human immunodeficiency virus-infected children in Cape Town, South Africa. Pediatr Infect Dis 30: 904-906. doi:10.1097/INF.0b013e318220a68b. PubMed: 21572372.
5. Aires de Sousa M, de Lencastre H, (2004) Bridges from hospitals to the laboratory: genetic portraits of methicillin resistant Staphylococcus aureus clones. FEMS Immunol Med Microbiol 40: 101-111. doi:10.1016/S0928-8244(03)00370-5. PubMed: 15040388.
6. Davis WG, White CE, (1974) Cloxacillin-resistant Staphylococcus aureus in a Children's Hospital. S Afr Med J 48: 1341-1344. PubMed: 4846427.
7. Friedland IR, du Plessis J, Cilliers A, (1995) Cardiac complications in children with Staphylococcus aureus bacteremia. J Pediatr 127: 746-748. doi:10.1016/S0022-3476(95)70166-4. PubMed: 7472829.
8. Bamford C, Bonorchis K, Ryan A, Simpson J, Elliott E, et al. (2010) Antimicrobial susceptibility patterns of selected bacteraemic isolates from South African public sector hospitals, 2010. S Afr J Epidemiol Infect 26(4)(Part II): 243-50.
9. Bouchillon SK, Johnson BM, Hoban DJ, Johnson JL, Dowzicky MJ, et al. (2004) Determining incidence of extended spectrum beta-lactamase producing Enterobacteriaceae, Vancomycin resistant Enterococcus faecium and methicillin resistant Staphylococcus aureus in 38 centers from 17 countries: the PEARLS Study 2001-2002 Int J Antimicrob Agents 24(2): 119-24.
10. Zinn CS, Westh H, Rosdahl VT and the SARISA study group,; Zinn CS, Westh H, Rosdahl VT, Sarisa Study Group, (2004) An international multicenter study of antimicrobial resistance and typing of hospital Staphylococcus aureus isolates from 21 laboratories in 19 countries or states. Microb Drug Resist 10(2):: 160-168. doi:10.1089/1076629041310055. PubMed: 15256032. doi:10.1089/1076629041310055 PubMed: 15256032.
11. Kaplan SL, (2005) Implications of methicillin-resistant Staphylococcus aureus as a community-acquired pathogen in pediatric patients. Infect Dis Clin North Am 19(3):: 747-757. doi:10.1016/j.idc.2005.05.011. PubMed: 16102659.
12. Otter JA, French GL, (2012) Community-associated methicillin resistant Staphylococcus aureus: the case for a genotypic definition. J Hosp Infect 81: 143-148. doi:10.1016/j.jhin.2012.04.009. PubMed: 22622448.
13. Jansen van Rensburg MJ, Madikane VE, Whitelaw A, Chachage M, Haffejee S, et al. (2011) The dominant methicillin-resistant Staphylococcus aureus clone from hospitals in Cape Town has an unusual genotype:ST612. Clin Microbiol Infect 17: 785-792. doi:10.1111/j.1469-0691.2010.03373.x. PubMed: 20854426.
14. Perovic O, Koornhof H, Black V, Moodley I, Duse A, et al. (2006) Staphylococcus aureus bacteraemia at two academic hospitals in Johannesburg. S Afr Med. p. pp. J 96(8): 714-7.
15. Clinical Laboratory Standards Institute (2006). erformance standards for antimicrobial susceptibility testing; Seventeenth informational supplement. CLSI Document M100-S17. Wayne, PA: Clinical and Laboratory Standards Institute.
16. Clinical Laboratory Standards Institute (2006) Performance standards for antimicrobial disk susceptibility tests; Approved standard-9th ed. CLSI document M2-A9. Wayne, PA: Clinical and Laboratory Standards Institute.
17. Klevens RM, Morrison MA, Nadle J, Petit S, Gershman K, et al. (2007) Invasive methicillin-resistant Staphylococcus aureus infections in the United States. JAMA 298: 1763-1771. doi:10.1001/jama.298.15.1763. PubMed: 17940231.
18. World Health Organization (1999) Management of severe malnutrition: a manual for physicians and other senior health workers. Geneva. Available: http://www.who.int/nutrition/publications/en/manage_severe_malnutrition_eng.pdf. Accessed 10 May 2012.
19. Department of Health, Republic of South Africa (June 22011) Integrated Manage Child Illn Man Accessed June 2,(2012).
20. Khairulddin N, Bishop L, Lamagni TL, Sharland M, Duckworth G, (2004) Emergence of methicillin resistant Staphylococcus aureus (MRSA) bacteraemia among children in England and Wales, 1990-2001. Arch Dis Child 89: 387-389. PubMed: 15033852.
21. Wisplinghoff H, Seifert H, Tallent SM, Bischoff T, Wenzel RP, et al. (2003) Nosocomial bloodstream infections in pediatric patients in United States hospitals: epidemiology, clinical features and susceptibilities. Pediatr Infect Dis J 22: 686-691. doi:10.1097/01.inf.0000078159.53132.40. PubMed: 12913767.
22. Burke RE, Halpern MS, Baron EJ, Gutierrez K, (2009) Pediatric and neonatal Staphylococcus aureus bacteraemia: Epidemiology, risk factors and outcome. Infect Control Hosp Epidemiol 30: 636-644. doi:10.1086/597521. PubMed: 19496643.
23. Suryati BA, Watson M, (2002) Staphylococcus aureus bacteraemia in children: a 5-year retrospective review. J Paediatr Child Health 38: 290-294. doi:10.1046/j.1440-1754.2002.00787.x. PubMed: 12047699.
24. Berkley JA, Lowe BS, Mwangi I, Williams T, Bauni E, et al. (2005) Bacteraemia among children admitted to a rural hospital in Kenya. N Engl J Med 352: 39-47. doi:10.1056/NEJMoa040275. PubMed: 15635111.
25. Nathoo KJ, Chigonde S, Nhembe M, Ali MH, Mason PR, (1996) Community-acquired bacteremia in human immunodeficiency virus-infected children in Harare, Zimbabwe. Pediatr Infect Dis J 15: 1092-1097. doi:10.1097/00006454-199612000-00007. PubMed: 8970218.
26. Frederiksen MS, Espersen F, Frimodt-Møller N, Jensen AG, Larsen AR, et al. (2007) Changing epidemiology of pediatric Staphylococcus aureus bacteremia in Denmark from 1971 through 2000. Pediatr Infect Dis J 26: 398-405. doi:10.1097/01.inf.0000261112.53035.4c. PubMed: 17468649.
27. Marais E, Aithma N, Perovic O, Oosthuysen WF, Musenge E, et al. (2009) Antimicrobial susceptibility of methicillin-resistant Staphylococcus aureus isolates from South Africa. S Afr Med J 99(3):: 170-173. PubMed: 19563094.
28. Shittu AO, Lin J, (2006) Antimicrobial susceptibility patterns and characterization of clinical isolates of Staphylococcus aureus in KwaZulu-Natal province, South Africa. BMC Infect Dis 6: 125. doi:10.1186/1471-2334-6-125. PubMed: 16875502.
29. Liu C, Bayer A, Cosgrove SE, Daum RS, Fridkin SK, et al. (2011) Clinical practice guidelines by the Infectious Diseases Society of America for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children. Clin Infect Dis 52(3):: e18-e55. doi:10.1093/cid/ciq146. PubMed: 21208910.