Increase in tetrahydrobiopterin concentration with aging in the cerebral cortex of the senescence-accelerated mouse prone 10 strain caused by abnormal regulation of tetrahydrobiopterin biosynthesis

Biogerontology

Volumn 14, Issue 5, 2013, Pages 491-501

  Miyajima, Miki ^a   Minoshima, Moemi ^a   Tanaka, Masato ^a   Nishimura, Ryo ^a   Hishioka, Naoko ^a   Numata, Takuya ^b   Hosokawa, Toshiyuki ^a   Kurasaki, Masaaki ^a   Saito, Takeshi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b Hakodate Junior College   (Japan)

Author keywords

Brain aging; Dihydrofolate reductase; Senescence accelerated mouse prone 10; Sepiapterin reductase; Tetrahydrobiopterin

Indexed keywords

DIHYDROFOLATE REDUCTASE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; SEPIAPTERIN REDUCTASE; TETRAHYDROBIOPTERIN; TYROSINE 3 MONOOXYGENASE;

AGING; ANIMAL EXPERIMENT; ARTICLE; BRAIN CORTEX; BRAIN METABOLISM; CATECHOLAMINE METABOLISM; CONTROLLED STUDY; GROUPS BY AGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SENESCENCE ACCELERATED MOUSE; WESTERN BLOTTING;

AGING; ANIMALS; BIOPTERIN; CEREBRAL CORTEX; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MICE; PHOSPHORYLATION; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 84885961573     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-013-9452-5     Document Type: Article

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