Evolution of the K65R, K103N and M184V/I reverse transcriptase mutations in HIV-1-infected patients experiencing virological failure between 2005 and 2010

Journal of Antimicrobial Chemotherapy

Volumn 68, Issue 10, 2013, Pages 2197-2198

  Charpentier, Charlotte ^a   Lambert Niclot, Sidonie ^b   Visseaux, Benoit ^a   Morand Joubert, Laurence ^b   Storto, Alexandre ^a   Larrouy, Lucile ^a   Landman, Roland ^c   Calvez, Vincent ^b   Marcelin, Anne Geneviève ^b   Descamps, Diane ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^c BICHAT HOSPITAL   (France)

Author keywords

Resistance prevalence; Single tablet regimens

Indexed keywords

EFAVIRENZ PLUS EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; RNA DIRECTED DNA POLYMERASE;

ANTIVIRAL THERAPY; ARTICLE; GENE MUTATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; LONGITUDINAL STUDY; MUTATION RATE; RETROSPECTIVE STUDY; VIRUS LOAD;

RESISTANCE PREVALENCE; SINGLE-TABLET REGIMENS;

AMINO ACID SUBSTITUTION; ANTI-HIV AGENTS; HIV INFECTIONS; HIV REVERSE TRANSCRIPTASE; HIV-1; HUMANS; LONGITUDINAL STUDIES; MUTATION, MISSENSE; PREVALENCE; RETROSPECTIVE STUDIES; TREATMENT FAILURE; WORLD HEALTH;

EID: 84885960814     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkt184     Document Type: Article

References (4)

1. Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected AdultsandAdolescents. Department of Health and Human Services, Washington, DC. http://www. aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf (25 February 2013, date last accessed).
2. Wainberg MA, Zaharatos GJ, Brenner BG. Development of antiretroviral drug resistance. N Engl J Med 2011; 365: 637-46.
3. Gardner EM, Sharma S, Peng G et al. Differential adherence to combination antiretroviral therapy is associated with virological failure with resistance. AIDS 2008; 22: 75-82.
4. Bangsberg DR, Ragland K, Monk A et al. A single-tablet regimen is associated with higher adherence and viral suppression than multiple tablet regimens in HIV+ homeless and marginally housed people. AIDS 2010; 24: 2835-40.