SGLT2 versus DPP4 inhibitors for type 2 diabetes

The Lancet Diabetes and Endocrinology

Volumn 1, Issue 3, 2013, Pages 168-170

  Scheen, André J ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CANAGLIFLOZIN; DAPAGLIFLOZIN; DIPEPTIDYL PEPTIDASE IV INHIBITOR; EMPAGLIFLOZIN; GLUCOSE; HEMOGLOBIN A1C; INSULIN; METFORMIN; ORAL ANTIDIABETIC AGENT; PLACEBO; SITAGLIPTIN; SODIUM GLUCOSE COTRANSPORTER 2; SODIUM GLUCOSE COTRANSPORTER 2 INHIBITOR; SULFONYLUREA DERIVATIVE; UNCLASSIFIED DRUG; BENZHYDRYL DERIVATIVE; GLUCOSIDE; PYRAZINE DERIVATIVE; TRIAZOLE DERIVATIVE;

BLOOD PRESSURE REGULATION; CONTROLLED CLINICAL TRIAL (TOPIC); DIET RESTRICTION; DIET THERAPY; DRUG COST; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; GASTROINTESTINAL DISEASE; GENITAL TRACT INFECTION; GLUCOSE BLOOD LEVEL; GLUCOSURIA; GLYCEMIC CONTROL; HUMAN; HYPERGLYCEMIA; HYPOGLYCEMIA; INSULIN RELEASE; KIDNEY TUBULE ABSORPTION; LETTER; MEDICAL DECISION MAKING; NON INSULIN DEPENDENT DIABETES MELLITUS; PRACTICE GUIDELINE; PRIORITY JOURNAL; SIDE EFFECT; SYSTOLIC BLOOD PRESSURE; TREATMENT DURATION; URINARY TRACT INFECTION; WEIGHT GAIN; WEIGHT REDUCTION; ANTAGONISTS AND INHIBITORS; DIABETES MELLITUS, TYPE 2; FEMALE; MALE;

BENZHYDRYL COMPOUNDS; DIABETES MELLITUS, TYPE 2; FEMALE; GLUCOSIDES; HUMANS; MALE; PYRAZINES; SODIUM-GLUCOSE TRANSPORTER 2; TRIAZOLES;

EID: 84885960694     PISSN: 22138587     EISSN: None     Source Type: Journal    
DOI: 10.1016/S2213-8587(13)70095-0     Document Type: Letter

References (10)

1. Scheen AJ A review of gliptins in 2011. Expert Opin Pharmacother 2012, 13:81-99.
2. Riser Taylor S, Harris KB The clinical efficacy and safety of sodium glucose cotransporter-2 inhibitors in adults with type 2 diabetes mellitus. Pharmacotherapy 2013, published online June 6. 10.1002/phar.1303.
3. Roden M, Weng J, Eilbracht J, et al. Empagliflozin monotherapy with sitagliptin as an active comparator in patients with type 2 diabetes: a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Diabetes Endocrinol 2013, published online Sept 9. http://dx.doi.org/10.1016/S2213-8587(13)70084-6.
4. Ferrannini E, Seman L, Seewaldt-Becker E, Hantel S, Pinnetti S, Woerle HJ A Phase IIb, randomized, placebo-controlled study of the SGLT2 inhibitor empagliflozin in patients with type 2 diabetes. Diabetes Obes Metab 2013, 15:721-728.
5. Scheen AJ DPP-4 inhibitors in the management of type 2 diabetes: a critical review of head-to-head trials. Diabetes Metab 2012, 38:89-101.
6. Rosenstock J, Seman LJ, Jelaska A, et al. Efficacy and safety of empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, as add-on to metformin in type 2 diabetes with mild hyperglycaemia. Diabetes Obes Metab 2013, published online Aug 1. 10.1111/dom.12185.
7. Rosenstock J, Aggarwal N, Polidori D, et al. Dose-ranging effects of canagliflozin, a sodium-glucose cotransporter 2 inhibitor, as add-on to metformin in subjects with type 2 diabetes. Diabetes Care 2012, 35:1232-1238.
8. Schernthaner G, Gross JL, Rosenstock J, et al. Canagliflozin compared with sitagliptin for patients with type 2 diabetes who do not have adequate glycemic control with metformin plus sulfonylurea: a 52-week randomized trial. Diabetes Care 2013, published online April 5. 10.2337/dc12-2491.
9. Scheen AJ Pharmacokinetic considerations for the treatment of diabetes in patients with chronic kidney disease. Expert Opin Drug Metab Toxicol 2013, 9:529-550.
10. Woerle HJ, Ferrannini E, Berk A, Manun'ebo M, Pinnetti S, Broedl UC Safety and efficacy of empagliflozin as monotherapy or add-on to metformin in a 78-week open-label extension study in patients with type 2 diabetes. Diabetes 2012, 61(Suppl). abstr 49-LB.