Dialysis in the frail elderly - A current ethical problem, an impending ethical crisis

Journal of General Internal Medicine

Volumn 28, Issue 11, 2013, Pages 1511-1516

  Thorsteinsdottir, Bjorg ^a   Swetz, Keith M ^a   Tilburt, Jon C ^a  

^a MAYO CLINIC   (United States)

Author keywords

ethics; health policy; Medicare; renal disease; shared decision making

Indexed keywords

BENEFICENCE; BIOETHICS; FINANCIAL MANAGEMENT; FRAIL ELDERLY; HEALTH CARE POLICY; HEMODIALYSIS; HUMAN; JUSTICE; MEDICAL ETHICS; PATIENT AUTONOMY; PATIENT INFORMATION; PATIENT RIGHT; PATIENT SAFETY; PHYSICIAN; REVIEW;

AGED; AGED, 80 AND OVER; FRAIL ELDERLY; HUMANS; MEDICARE; PATIENT PARTICIPATION; PHYSICIAN-PATIENT RELATIONS; PROFESSIONAL AUTONOMY; RENAL DIALYSIS; UNITED STATES;

EID: 84885956642     PISSN: 08848734     EISSN: 15251497     Source Type: Journal    
DOI: 10.1007/s11606-013-2494-1     Document Type: Review

References (75)

1. Alexander S. They decide who lives, who dies: medical miracle puts a moral burden on a small committee. Life. 1962:102-4, 6, 8, 10, 15, 17, 18, 23, 24.
2. Rettig RA. Special treatment-the story of Medicare's ESRD entitlement. N Engl J Med. 2011;364:596-8.
3. Kjellstrand C. All elderly patients should be offered dialysis. Geriatr Nephrol Urol. [Editorial comment]. 1997;6:129-36.
4. Butler RN. Age-ism: another form of bigotry. Gerontologist. 1969;9:243-6.
5. Avorn J. Benefit and cost analysis in geriatric care. Turning age discrimination into health policy. N Engl J Med. 1984;310:1294-301.
6. U. S. Renal Data System. USRDS 2011 Annual Data Report: Atlas of End-Stage Renal Disease in the United States. Bethesda: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases; 2011.
7. Kurella M, Covinsky KE, Collins AJ, Chertow GM. Octogenarians and nonagenarians starting dialysis in the United States. Ann Intern Med. 2007;146:177-83.
8. Rosansky SJ. The sad truth about early initiation of dialysis in elderly patients. JAMA. 2012;307:1919-20.
9. Williams AW, Dwyer AC, Eddy AA, et al. Critical and honest conversations: the evidence behind the "Choosing Wisely" campaign recommendations by the American Society of Nephrology. Clin J Am Soc Nephrol. 2012;7:1664-72.
10. Kolata G. When Ailments Pile Up, Asking Patients to Rethink Free Dialysis. New York Times; 2011.
11. Russ AJ, Shim JK, Kaufman SR. "Is there life on dialysis?": time and aging in a clinically sustained existence. Med Anthropol. 2005;24:297-324.
12. Kurella Tamura M, Covinsky KE, Chertow GM, Yaffe K, Landefeld CS, McCulloch CE. Functional status of elderly adults before and after initiation of dialysis. N Engl J Med. 2009;361:1539-47.
13. Jassal SV, Chiu E, Hladunewich M. Loss of independence in patients starting dialysis at 80 years of age or older. N Engl J Med. 2009;361:1612-3.
14. Murtagh FEM, Addington-Hall J, Higginson IJ. The Prevalence of Symptoms in End-Stage Renal Disease: A Systematic Review. Adv Chronic Kidney Dis. 2007;14:82-99.
15. Kaufman SR, Shim JK, Russ AJ. Revisiting the biomedicalization of aging: clinical trends and ethical challenges. Gerontologist. 2004;44:731-8.
16. Pence G. Classic Cases in Medical Ethics: Accounts of Cases That Have Shaped Medical Ethics with Philosophical, Legal and Historical Backgrounds. 4th ed. New York: McGraw-Hill; 2003.
17. Davison SN. End-of-life care preferences and needs: perceptions of patients with chronic kidney disease. Clin J Am Soc Nephrol. 2010;5:195-204.
18. Russ AJ, Kaufman SR. Discernment rather than decision-making among elderly dialysis patients. Semin Dial. 2012;25:31-2.
19. Stringer S, Baharani J. Why did I start dialysis? A qualitative study on views and expectations from an elderly cohort of patients with end-stage renal failure starting haemodialysis in the United Kingdom. Int Urol Nephrol. 2012;44:295-300.
20. Fine A, Fontaine B, Kraushar MM, Rich BR. Nephrologists should voluntarily divulge survival data to potential dialysis patients: a questionnaire study. Perit Dial Int. 2005;25:269-73.
21. Morton RL, Tong A, Howard K, Snelling P, Webster AC. The views of patients and carers in treatment decision making for chronic kidney disease: systematic review and thematic synthesis of qualitative studies. BMJ. 2010;340:c112.
22. Pellegrino ED. Medical ethics in an era of bioethics: resetting the medical profession's compass. Theor Med Bioeth. 2012;33:21-4.
23. Kaufman SR. and a time to die. How American Hospitals Shape the End of Life. Chicago: The University of Chicago Press; 2005.
24. Caplan AL. Little hope for medical futility. Mayo Clin Proc. 2012;87:1040-1.
25. [No authors listed]. Medical futility in end-of-life care: report of the Council on Ethical and Judicial Affairs. JAMA. 1999;281:937-41.
26. Cooper BA, Branley P, Bulfone L, et al. A randomized, controlled trial of early versus late initiation of dialysis. N Engl J Med. 2010;363:609-19.
27. Winkelmayer WC, Liu J, Chertow GM, Tamura MK. Predialysis nephrology care of older patients approaching end-stage renal disease. Arch Intern Med. 2011;171:1371-8.
28. Keith DS, Nichols GA, Gullion CM, Brown JB, Smith DH. Longitudinal follow-up and outcomes among a population with chronic kidney disease in a large managed care organization. Arch Intern Med. 2004;164:659-63.
29. Fenton SS, Schaubel DE, Desmeules M, et al. Hemodialysis versus peritoneal dialysis: a comparison of adjusted mortality rates. Am J Kidney Dis. 1997;30:334-42.
30. Mitka M. Developed countries lag in use of cheaper and easier peritoneal dialysis. JAMA. 2012;307:2360-1.
31. Theofilou P. Quality of life in patients undergoing hemodialysis or peritoneal dialysis treatment. J Clin Med Res. 2011;3:132-8.
32. Cohen LM, Moss AH, Weisbord SD, Germain MJ. Renal palliative care. J Palliat Med. 2006;9:977-92.
33. Barakzoy AS, Moss AH. Efficacy of the world health organization analgesic ladder to treat pain in end-stage renal disease. J Am Soc Nephrol. 2006;17:3198-203.
34. Hurst SA, Hull SC, DuVal G, Danis M. How physicians face ethical difficulties: a qualitative analysis. J Med Ethics. 2005;31:7-14.
35. Gronlund CE, Dahlqvist V, Soderberg AI. Feeling trapped and being torn: physicians' narratives about ethical dilemmas in hemodialysis care that evoke a troubled conscience. BMC Med Ethics. 2011;12:8.
36. Abadir PM, Finucane TE, McNabney MK. When doctors and daughters disagree: twenty-two days and two blinks of an eye. J Am Geriatr Soc. 2011;n/a-n/a.
37. Abadir PM, Finucane TE, McNabney MK. When doctors and daughters disagree: twenty-two days and two blinks of an eye. J Am Geriatr Soc. 2011;59:2337-40.
38. Berns JS. A Survey-Based Evaluation of Self-Perceived Competency after Nephrology Fellowship Training. Clin J Am Soc Nephrol. 2010;5:490-6.
39. Davison SN, Jhangri GS, Holley JL, Moss AH. Nephrologists' reported preparedness for end-of-life decision-making. Clin J Am Soc Nephrol. 2006;1:1256-62.
40. Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56:M146-56.
41. Couchoud C. Dialysis: Can we predict death in patients on dialysis? Nat Rev Nephrol. 2010;6:388-9.
42. Kaufman SR. Making longevity in an aging society: linking Medicare policy and the new ethical field. Perspect Biol Med. 2010;53:407-24.
43. Fuchs VR. The growing demand for medical care. N Engl J Med. 1968;279:190-5.
44. Koenig B, ed. The Technological Imperitives in Medical Practice. Boston: Kluwer; 1988.
45. O'Connor NR, Kumar P. Conservative management of end-stage renal disease without dialysis: a systematic review. J Palliat Med. 2012;15:228-35.
46. Chandna SM, Da Silva-Gane M, Marshall C, Warwicker P, Greenwood RN, Farrington K. Survival of elderly patients with stage 5 CKD: comparison of conservative management and renal replacement therapy. Nephrol Dial Transplant. 2011;26:1608-14.
47. Gorodetskaya I, Zenios S, McCulloch CE, et al. Health-related quality of life and estimates of utility in chronic kidney disease. Kidney Int. 2005;68:2801-8.
48. Yong DS, Kwok AO, Wong DM, Suen MH, Chen WT, Tse DM. Symptom burden and quality of life in end-stage renal disease: a study of 179 patients on dialysis and palliative care. Palliat Med. 2009;23:111-9.
49. Visser A, Dijkstra GJ, Kuiper D, et al. Accepting or declining dialysis: considerations taken into account by elderly patients with end-stage renal disease. J Nephrol. 2009;22:794-9.
50. Haberle TH, Shinkunas LA, Erekson ZD, Kaldjian LC. Goals of care among hospitalized patients: a validation study. Am J Hosp Palliat Care. 2011;28:335-41.
51. Kaufman SR. Making longevity in an aging society: linking ethical sensibility and Medicare spending. Med Anthropol. 2009;28:317-25.
52. Hauksdottir A, Steineck G, Furst CJ, Valdimarsdottir U. Long-term harm of low preparedness for a wife's death from cancer-a population-based study of widowers 4-5 years after the loss. Am J Epidemiol. 2010;172:389-96.
53. Valdimarsdottir U, Helgason AR, Furst CJ, Adolfsson J, Steineck G. Awareness of husband's impending death from cancer and long-term anxiety in widowhood: a nationwide follow-up. Palliat Med. 2004;18:432-43.
54. Wendler D, Rid A. Systematic review: the effect on surrogates of making treatment decisions for others. Ann Intern Med. 2011;154:336-46.
55. Pellegrino ED. Decisions to withdraw life-sustaining treatment: a moral algorithm. JAMA. 2000;283:1065-7.
56. Murtagh FE, Addington-Hall JM, Higginson IJ. End-stage renal disease: a new trajectory of functional decline in the last year of life. J Am Geriatr Soc. 2011;59:304-8.
57. Murray AM, Arko C, Chen SC, Gilbertson DT, Moss AH. Use of hospice in the United States dialysis population. Clin J Am Soc Nephrol. 2006;1:1248-55.
58. U. S. Renal Data System. USRDS 1994 Annual Data Report. Bethesda: The National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases; 1994.
59. U. S. Renal Data System. USRDS 2008 Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States. Bethesda: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases; 2008.
60. Wong CF, McCarthy M, Howse ML, Williams PS. Factors affecting survival in advanced chronic kidney disease patients who choose not to receive dialysis. Ren Fail. 2007;29:653-9.
61. Gomes B, Higginson IJ, Calanzani N, et al. Preferences for place of death if faced with advanced cancer: a population survey in England, Flanders, Germany, Italy, the Netherlands, Portugal and Spain. Ann Oncol. 2012;23:2006-15.
62. A controlled trial to improve care for seriously ill hospitalized patients. The study to understand prognoses and preferences for outcomes and risks of treatments (SUPPORT). The SUPPORT Principal Investigators. JAMA. 1995;274:1591-8.
63. Rakowski DA, Caillard S, Agodoa LY, Abbott KC. Dementia as a predictor of mortality in dialysis patients. Clin J Am Soc Nephrol. 2006;1:1000-5.
64. Beauchamp T, Childress J. Principles of Biomedical Ethics. 5th ed. New York: Oxford University Press; 2001.
65. Earle CC, Landrum MB, Souza JM, Neville BA, Weeks JC, Ayanian JZ. Aggressiveness of cancer care near the end of life: is it a quality-of-care issue? J Clin Oncol. 2008;26:3860-6.
66. Sharma G, Freeman J, Zhang D, Goodwin JS. Trends in end-of-life ICU use among older adults with advanced lung cancer. Chest. 2008;133:72-8.
67. Kilner JF. Age as a basis for allocating lifesaving medical resources: an ethical analysis. J Health Polit Policy Law. 1988;13:405-23.
68. Butler RN. Declaration of the rights of older persons. Gerontologist. 2002;42:152-3.
69. Pelligrino ED. Rationing health care: the ethics of medical gatekeeping. J Contemp Health Law Policy. 1986;2:23-45.
70. Rubin R. Dialysis treatment in USA: high costs, high death rates. USA Today [serial on the Internet]. 2009 August 15, 2012: Available from: http://www.usatoday.com/news/health/2009-08-23-dialysis-N.htm.
71. Schlesinger M, Cleary PD, Blumenthal D. The ownership of health facilities and clinical decisionmaking. The case of the ESRD industry. Med Care. 1989;27:244-58.
72. Desai AA, Bolus R, Nissenson A, et al. Is there "cherry picking" in the ESRD Program? Perceptions from a Dialysis Provider Survey. Clin J Am Soc Nephrol. 2009;4:772-7.
73. Sabin JA, Rivara FP, Greenwald AG. Physician implicit attitudes and stereotypes about race and quality of medical care. Med Care. 2008;46:678-85.
74. Kee F, Patterson CC, Wilson EA, McConnell JM, Wheeler SM, Watson JD. Stewardship or clinical freedom? variations in dialysis decision making. Nephrol Dial Transplant. 2000;15:1647-57.
75. Sulmasy DP. Physicians, cost control, and ethics. Ann Intern Med. 1992;116:920-6.