Development and validation of automated SPE-LC-MS/MS method for determination of indapamide in human whole blood and its application to real study samples

Biomedical Chromatography

Volumn 27, Issue 11, 2013, Pages 1540-1546

  Nakov, N ^a   Mladenovska, K ^a   Labacevski, N ^b   Dimovski, A ^a   Petkovska, R ^a   Dimitrovska, A ^a   Kavrakovski, Z ^a  

^a SS Cyril and Methodius University Faculty of Pharmacy   (Macedonia)

^b SS CYRIL AND METHODIUS UNIVERSITY   (Macedonia)

Author keywords

Human whole blood; Indapamide; LC MS MS; Pharmacokinetics

Indexed keywords

BLOOD; ELECTROSPRAY IONIZATION; EXTRACTION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PARTICLE SIZE; PHASE SEPARATION;

HUMAN WHOLE BLOOD; INDAPAMIDE; ITS APPLICATIONS; LC-MS-MS; LC.MS/MS; LIQUID CHROMATOGRAPHY ELECTROSPRAY; SIMPLE LIQUIDS; SPE-LC-MS; STUDY SAMPLES; WHOLE BLOOD;

PHARMACOKINETICS;

INDAPAMIDE; ZOLPIDEM TARTRATE;

ADULT; ANALYTICAL EQUIPMENT; ARTICLE; AUTOMATION; BLOOD SAMPLING; DRUG BLOOD LEVEL; DRUG DETERMINATION; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETER; MASS SPECTROMETRY; NORMAL HUMAN; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; SINGLE DRUG DOSE; SOLID PHASE EXTRACTION; SUSTAINED RELEASE FORMULATION; TABLET FORMULATION; TANDEM MASS SPECTROMETRY; VALIDATION STUDY;

HUMAN WHOLE BLOOD; INDAPAMIDE; LC-MS/MS; PHARMACOKINETICS;

ADULT; ANTIHYPERTENSIVE AGENTS; CHROMATOGRAPHY, LIQUID; HUMANS; INDAPAMIDE; LIMIT OF DETECTION; MALE; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 84885936904     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.2957     Document Type: Article

References (13)

1. Dollery C. Therapeutic Drugs, 2nd edition. Churchill Livingstone: Edinburgh, 1999.
2. Eeckhaut AV, Lanckmans K, Sarre S, Smolders I and Michotte Y. Validation of bioanalytical LC-MS/MS assays: Evaluation of matrix effects. Journal of Chromatography B 2009; 877: 2198-2207.
3. European Medicines Agency. Guideline on Validation of Bioanalytical Methods. Committee for Medical Products for Human Use, 2011. Available from: http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2011/08/WC500109686.pdf
4. Hang TJ, Zhao W, Liu J, Song M, Xie Y, Zhang Z, Shen J and Zhang Y. A selective HPLC method for the determination of indapamide in human whole blood: application to a bioequivalence study in Chinese volunteers. Journal of Pharmaceutical and Biomedical Analysis 2006; 40(1): 202-205.
5. Jain DS, Subbaiah G, Sanyal M, Pande UC and Shrivastav P. Liquid chromatography-tandem mass spectrometry validated method for estimation of indapamide in human whole blood. Journal of Chromatography B 2006; 834: 149-154.
6. MHRA. Public Assessment Report. Indapres XL prolonged-release tablets 1.5 mg. UK/H/1052/001/DC. decentralised procedure, 2008. Available from: http://www.mhra.gov.uk/home/groups/pla/documents/websiteresources/con017782.pdf (accessed 11 June 2013).
7. Miller RB, Dadgar D and Lalande M. High performance liquid chromatographic method for the determination of indapamide in human whole blood. Journal of Chromatography 1993; 614(2): 293-298.
8. Robinson DM and Wellington K. Indapamide sustained release - a review of its use in the treatment of hypertension. Drugs 2006; 66(2): 257-271.
9. Schiavi P, Jochemsen R and Guez D. Pharmacokinetics of sustained and immediate release formulations of indapamide after single and repeated oral administration in healthy volunteers. Fundamental & Clinical Pharmacology 2000; 14(2): 139-146.
10. Tang J, Li J, Sun J, Yin J and He Z. Rapid and sensitive determination of indapamide in human blood by liquid chromatography with electrospray ionization mass spectrometric detection: application to a bioequivalence study. Pharmazie 2005; 60(11): 819-822.
11. Taylor PJ. Matrix effects: the Achilles heel of quantitative high-performance liquid chromatography-electrospray-tandem mass spectrometry. Clinical Biochemistry 2005; 38: 328-334.
12. Zendelovska D, Stafilov T and Stefova M. Optimization of solid-phase extraction method for determination of indapamide in biological fluids using high performance liquid chromatography. Journal of Chromatography B 2003; 788(1): 199-206.
13. Zhao L, Gu S, Xu R, Cui X, Gan F and Chen H. Comparison of liquid chromatography-ultraviolet and chromatography-tandem mass spectrometry for the determination of indapamide in human whole blood and their applications in bioequivalence studies. Arzneimittel-Forschung 2010; 60(7): 432-439.