-
1
-
-
85028248444
-
Autonomia e responsabilidade da pessoa
-
in Actas do IV SeminA&Acute; rio do Conselho Nacional de É tica para as Ciências da Vida (eds Lisboa: Conselho Nacional de É tica para as Ciências da Vida
-
Patrão Neves MC. Autonomia e responsabilidade da pessoa; in Actas do IV SeminA&Acute; rio do Conselho Nacional de É tica para as Ciências da Vida (eds) Poderes e limites da genÉtica. Lisboa: Conselho Nacional de É tica para as Ciências da Vida, 1997; pp 3-8.
-
(1997)
Poderes e Limites da GenÉtica
, pp. 3-8
-
-
Patrão Neves, M.C.1
-
3
-
-
79952654904
-
A method to estimate the costs of lives in ethical board review of biomedical research
-
Whitney SN, Schneider CE. A method to estimate the costs of lives in ethical board review of biomedical research. J Int Med. 2011; 269: 392-406.
-
(2011)
J Int Med
, vol.269
, pp. 392-406
-
-
Whitney, S.N.1
Schneider, C.E.2
-
4
-
-
16644362619
-
The rebirth of bioethics: Extending the original formulations of van Rensselaer Potter
-
Whitehouse P. The rebirth of bioethics: extending the original formulations of van Rensselaer Potter. Am J Bioeth. 2003; 3: 26-31.
-
(2003)
Am J Bioeth
, vol.3
, pp. 26-31
-
-
Whitehouse, P.1
-
5
-
-
84859731650
-
Bioethics critically reconsidered: Living after foundations
-
Tristram Engelhardt Jr H. Bioethics critically reconsidered: living after foundations. Theor Med Bioeth. 2012; 33: 97-105.
-
(2012)
Theor Med Bioeth
, vol.33
, pp. 97-105
-
-
Tristram Engelhardt, H.1
-
6
-
-
85028275301
-
BioÉ tica: Avassaladora, porquê?
-
Archer L. BioÉ tica: avassaladora, porquê?. BrotÉria. 1996; 142: 449-472.
-
(1996)
BrotÉria
, vol.142
, pp. 449-472
-
-
Archer, L.1
-
8
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science. 1998; 282: 1145-1147.
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
-
9
-
-
0032506231
-
Derivation of pluripotent stem cells from cultured human primordial cells
-
Shamblott MJ, Axelman J, Wang S, et al. Derivation of pluripotent stem cells from cultured human primordial cells. Proc Natl Acad Sci USA. 1998; 95: 13726-13731.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13726-13731
-
-
Shamblott, M.J.1
Axelman, J.2
Wang, S.3
-
10
-
-
85028268597
-
-
European Group on Ethics in Science and New Technologies (EGE). Opinion no 15
-
European Group on Ethics in Science and New Technologies (EGE). Opinion no 15 Regarding Ethical Aspects of Human Stem Cell Research and UseBrussels, 2000 in. http://ec.europa.eu/european-group-ethics/docs/avis15-en.pdf
-
(2000)
Regarding Ethical Aspects of Human Stem Cell Research and UseBrussels
-
-
-
12
-
-
0033961920
-
Human embryonic stem cell and embryonic germ line
-
Thomson JA, Odorico JS. Human embryonic stem cell and embryonic germ line. Trends Biotech. 2000; 18: 53-57.
-
(2000)
Trends Biotech
, vol.18
, pp. 53-57
-
-
Thomson, J.A.1
Odorico, J.S.2
-
14
-
-
67649573353
-
-
National Institutes of Health (NIH): Stem Cells: Scientific Progress and Future Research Directions. Maryland
-
National Institutes of Health (NIH): Stem Cells: Scientific Progress and Future Research Directions. Maryland: Department of Health and Human Services, 2001 in. http://stemcells.nih.gov/info/2001report/2001report.htm
-
(2001)
Department of Health and Human Services
-
-
-
15
-
-
79957525813
-
Human procreation in unchartered territory: New twists in ethical discussions
-
Ramalho-Santos J. Human procreation in unchartered territory: new twists in ethical discussions. Hum Reprod. 2011; 26: 1284-1287.
-
(2011)
Hum Reprod
, vol.26
, pp. 1284-1287
-
-
Ramalho-Santos, J.1
-
16
-
-
50849106701
-
Sources of stem cells for regenerative medicine
-
Hipp J, Atala A. Sources of stem cells for regenerative medicine. Stem Cell Rev. 2008; 4: 3-11.
-
(2008)
Stem Cell Rev
, vol.4
, pp. 3-11
-
-
Hipp, J.1
Atala, A.2
-
17
-
-
0345537461
-
Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells
-
Broxmeyer H, Douglas GH, Hangoc G, et al. Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells. Proc Natl Acad Sci USA. 1989; 86: 3828-3832.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 3828-3832
-
-
Broxmeyer, H.1
Douglas, G.H.2
Hangoc, G.3
-
18
-
-
70350463831
-
Cord blood for tissue regeneration
-
Buchheiser A, Liedtke S, Leendert H, Looijenga J, Kogler G. Cord blood for tissue regeneration. J Cell Biochem. 2009; 108: 762-768.
-
(2009)
J Cell Biochem
, vol.108
, pp. 762-768
-
-
Buchheiser, A.1
Liedtke, S.2
Leendert, H.3
Looijenga, J.4
Kogler, G.5
-
20
-
-
84882535527
-
-
President Council on Bioethics: White Paper: Alternative Sources of Pluripotent Stem Cells
-
President Council on Bioethics: White Paper: Alternative Sources of Pluripotent Stem Cells. The President's Council on Bioethics, 2005 in. http://bioethics.georgetown.edu/.pcbe/reports/white-paper/.
-
(2005)
The President's Council on Bioethics
-
-
-
21
-
-
0033593654
-
Turning brain into blood: A hematopoietic fate adopted by adult neural stem cells in vivo
-
Bjornson CR, Rietze RL, Reynolds BA, Magli MC, Vescovi AL. Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo. Science. 1999; 283: 534-537.
-
(1999)
Science
, vol.283
, pp. 534-537
-
-
Bjornson, C.R.1
Rietze, R.L.2
Reynolds, B.A.3
Magli, M.C.4
Vescovi, A.L.5
-
22
-
-
1542328965
-
Plasticity of adult stem cells
-
Wagers A, Irving J, Weissman L. Plasticity of adult stem cells. Cell. 2004; 116: 639-648.
-
(2004)
Cell
, vol.116
, pp. 639-648
-
-
Wagers, A.1
Irving, J.2
Weissman, L.3
-
23
-
-
43049161115
-
Self-renewal and differentiation capacity of young and aged stem cells
-
Roobrouck VD, Ulloa-Montoya F, Verfaillie CM. Self-renewal and differentiation capacity of young and aged stem cells. Exp Cell Res. 2008; 314: 1937-1944.
-
(2008)
Exp Cell Res
, vol.314
, pp. 1937-1944
-
-
Roobrouck, V.D.1
Ulloa-Montoya, F.2
Verfaillie, C.M.3
-
24
-
-
56749160139
-
Generation of pluripotent stem cells from adult human testis
-
Conrad S, Renninger M, Hennenlotter J, et al. Generation of pluripotent stem cells from adult human testis. Nature. 2008; 456: 344-349.
-
(2008)
Nature
, vol.456
, pp. 344-349
-
-
Conrad, S.1
Renninger, M.2
Hennenlotter, J.3
-
25
-
-
59849129677
-
Isolation and characterization of pluripotent human spermatogonial stem cell-derived cells
-
Kossack N, Meneses J, Shefi S, et al. Isolation and characterization of pluripotent human spermatogonial stem cell-derived cells. Stem Cells. 2009; 27: 138-149.
-
(2009)
Stem Cells
, vol.27
, pp. 138-149
-
-
Kossack, N.1
Meneses, J.2
Shefi, S.3
-
26
-
-
84856489247
-
Can adult neural stem cells create new brains?. Plasticity in the adult mammalian neurogenic niches: Realities and expectations in the era of regenerative biology
-
Kazanis I. Can adult neural stem cells create new brains?. Plasticity in the adult mammalian neurogenic niches: realities and expectations in the era of regenerative biology. Neuroscientist. 2012; 18: 15-27.
-
(2012)
Neuroscientist
, vol.18
, pp. 15-27
-
-
Kazanis, I.1
-
27
-
-
0037019337
-
Pluripotency of mesenchymal stem cells derived from adult marrow
-
Jiang Y, Jahagirdar BN, Reinhardt RL, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature. 2002; 418: 41-49.
-
(2002)
Nature
, vol.418
, pp. 41-49
-
-
Jiang, Y.1
Jahagirdar, B.N.2
Reinhardt, R.L.3
-
28
-
-
34547697325
-
Breakdown of the potentiality principle and its impact on global stem cell research
-
Testa G, Borghese L, Steinbeck JA, Brostle O. Breakdown of the potentiality principle and its impact on global stem cell research. Cell Stem Cell. 2007; 1: 153-156.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 153-156
-
-
Testa, G.1
Borghese, L.2
Steinbeck, J.A.3
Brostle, O.4
-
29
-
-
33746920868
-
Nonviable human pre-implantation embryos as a source of stem cells for research and potential therapy
-
Alikani M, MunnÉ S. Nonviable human pre-implantation embryos as a source of stem cells for research and potential therapy. Stem Cell Rev Rep. 2005; 1: 337-343.
-
(2005)
Stem Cell Rev Rep
, vol.1
, pp. 337-343
-
-
Alikani, M.1
MunnÉ, S.2
-
30
-
-
30544449468
-
Generation of nuclear transfer-derived pluripotent ES cells from cloned Cdx2-deficient blastocysts
-
Meissner A, Jaenisch R. Generation of nuclear transfer-derived pluripotent ES cells from cloned Cdx2-deficient blastocysts. Nature, 439: 212-215.
-
Nature
, vol.439
, pp. 212-215
-
-
Meissner, A.1
Jaenisch, R.2
-
31
-
-
77952090803
-
Derivation of new human embryonic stem cell lines from preimplantation genetic screening and diagnosis-Analyzed embryos
-
Taei A, Gourabi H, Seifinejad A, et al. Derivation of new human embryonic stem cell lines from preimplantation genetic screening and diagnosis-Analyzed embryos. In Vitro Cell Dev Biol Anim. 2010; 46: 395-402.
-
(2010)
Vitro Cell Dev Biol Anim
, vol.46
, pp. 395-402
-
-
Taei, A.1
Gourabi, H.2
Seifinejad, A.3
-
32
-
-
70350050399
-
Human parthenogenetic embryonic stem cells: One potential resource for cell therapy
-
Hao J, Zhu W, Sheng C, Yu Y, Zhou Q. Human parthenogenetic embryonic stem cells: one potential resource for cell therapy. Sci China C Life Sci. 2009; 52: 599-602.
-
(2009)
Sci China C Life Sci
, vol.52
, pp. 599-602
-
-
Hao, J.1
Zhu, W.2
Sheng, C.3
Yu, Y.4
Zhou, Q.5
-
33
-
-
0035221762
-
Human embryonic stem cell research: Ethical and legal issues
-
Robertson JA. Human embryonic stem cell research: ethical and legal issues. Nat Rev Genet. 2001; 2: 74-78.
-
(2001)
Nat Rev Genet
, vol.2
, pp. 74-78
-
-
Robertson, J.A.1
-
34
-
-
0036296354
-
Stem cells, embryos and cloning - Unraveling the ethics of knotty debate
-
Bruce DM. Stem cells, embryos and cloning - unraveling the ethics of knotty debate. J Mol Biol. 2002; 319: 917-925.
-
(2002)
J Mol Biol
, vol.319
, pp. 917-925
-
-
Bruce, D.M.1
-
36
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006; 126: 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
37
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007; 131: 861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
-
38
-
-
60649084367
-
Induced pluripotent stem cells: Current progress and potential for regenerative medicine
-
Amabile G, Meissner A. Induced pluripotent stem cells: current progress and potential for regenerative medicine. Trends Mol Med. 2009; 15: 59-68.
-
(2009)
Trends Mol Med
, vol.15
, pp. 59-68
-
-
Amabile, G.1
Meissner, A.2
-
39
-
-
77955948581
-
Complicity in stem cell research: The case of induced pluripotent stem cells
-
Devolder K. Complicity in stem cell research: the case of induced pluripotent stem cells. Hum Reprod. 2010; 25: 2175-2180.
-
(2010)
Hum Reprod
, vol.25
, pp. 2175-2180
-
-
Devolder, K.1
-
40
-
-
77955449906
-
Epigenetic memory in induced pluripotent stem cells
-
Kim K, Doi A, Wen B, et al. Epigenetic memory in induced pluripotent stem cells. Nature. 2010; 467: 285-290.
-
(2010)
Nature
, vol.467
, pp. 285-290
-
-
Kim, K.1
Doi, A.2
Wen, B.3
-
41
-
-
79551677421
-
Reference maps of human ES and iPS cell variation enable high-Throughput characterization of puripotent cell lines
-
Bock C, Kiskinis E, Verstappen G, et al. Reference maps of human ES and iPS cell variation enable high-Throughput characterization of puripotent cell lines. Cell. 2011; 144: 439-452.
-
(2011)
Cell
, vol.144
, pp. 439-452
-
-
Bock, C.1
Kiskinis, E.2
Verstappen, G.3
-
42
-
-
79952258224
-
Somatic coding mutations in human induced pluripotent stem cells
-
Gore A, Li Z, Fung H-L, Young JE, et al. Somatic coding mutations in human induced pluripotent stem cells. Nature. 2011; 471: 63-67.
-
(2011)
Nature
, vol.471
, pp. 63-67
-
-
Gore, A.1
Li, Z.2
Fung, H.-L.3
Young, J.E.4
-
43
-
-
79952126043
-
Copy number variation and selection during reprogramming to pluripotency
-
Hussein SM, Batada NN, Vuoristo S, et al. Copy number variation and selection during reprogramming to pluripotency. Nature. 2011; 471: 58-62.
-
(2011)
Nature
, vol.471
, pp. 58-62
-
-
Hussein, S.M.1
Batada, N.N.2
Vuoristo, S.3
-
44
-
-
79952264847
-
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent cells
-
Lister R, Pelizzola M, Kida YS, et al. Hotspots of aberrant epigenomic reprogramming in human induced pluripotent cells. Nature. 2011; 471: 68-73.
-
(2011)
Nature
, vol.471
, pp. 68-73
-
-
Lister, R.1
Pelizzola, M.2
Kida, Y.S.3
-
45
-
-
34249977050
-
Simple switch turns cells embryonic
-
Cyranoski D, Ledford H. Simple switch turns cells embryonic. Nature. 2007; 447: 618-619.
-
(2007)
Nature
, vol.447
, pp. 618-619
-
-
Cyranoski, D.1
Ledford, H.2
-
46
-
-
0034231475
-
Going to the roots of the stem cell debate
-
Mieth D. Going to the roots of the stem cell debate. EMBO Rep. 2000; 1: 4-6.
-
(2000)
EMBO Rep
, vol.1
, pp. 4-6
-
-
Mieth, D.1
|