Expression of SAP5 and SAP9 in Candida albicans biofilms: Comparison of bloodstream isolates with isolates from other sources

Medical Mycology

Volumn 51, Issue 8, 2013, Pages 892-896

  Joo, Min Young ^a   Shin, Jong Hee ^a   Jang, Hee Chang ^a   Song, Eun Song ^a   Kee, Seung Jung ^a   Shin, Myung Geun ^a   Suh, Soon Pal ^a   Ryang, Dong Wook ^a  

^a Chonnam National University Medical School   (South Korea)

Author keywords

Biofilm; Bloodstream infections; Candida albicans; SAP genes

Indexed keywords

ARTICLE; BIOFILM; BLOODSTREAM INFECTION; CANDIDA ALBICANS; CANDIDIASIS; FUNGAL GENE; FUNGUS GROWTH; FUNGUS ISOLATION; GENE EXPRESSION; HUMAN; IN VITRO STUDY; NONHUMAN; PLANKTON; SAP5 GENE; SAP9 GENE;

CANDIDA ALBICANS;

ASPARTIC ACID ENDOPEPTIDASES; BIOFILMS; CANDIDA ALBICANS; CANDIDIASIS; FUNGAL PROTEINS; GENE EXPRESSION PROFILING; HUMANS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VIRULENCE FACTORS;

EID: 84885913914     PISSN: 13693786     EISSN: 14602709     Source Type: Journal    
DOI: 10.3109/13693786.2013.824623     Document Type: Article

References (16)

1. Naglik JR, Challacombe SJ, Hube B . C andida albicans secreted aspartyl proteinases in virulence and pathogenesis . Microbiol Mol Biol Rev 2003 ; 67: 400-428
2. Ramage G, Martinez JP, Lopez-Ribot JL . C andida biofilms on implanted biomaterials: A clinically signifi cant problem . FEMS Yeast Res 2006 ; 6: 979-986
3. Crump JA, Collignon PJ . Intravascular catheter-associated infections. Eur J Clin Microbiol Infect Dis 2000 ; 19: 1-8
4. Naglik JR, Moyes D, Markwana J, e t al . Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis . Microbiology 2008 ; 154: 3266-3280
5. Mendes A, Mores AU, Carvalho AP, e t al . Candida albicans biofilms produce more secreted aspartyl protease than the planktonic cells . Biol Pharm Bull 2007 ; 30: 1813-1815
6. Ramage G, Coco B, Sherry L, et al . In vitro C andida albicans biofi lm induced proteinase activity and SAP8 expression correlates with in vivo denture stomatitis severity . Mycopathologia 2012 ; 174: 11-19
7. Ricicov á M, Kuchar í kov á S, Tournu H, et al . Candida albicans biofi lm formation in a new in vivo rat model . Microbiology 2010 ; 156: 909-919
8. Chaffi n WL . Candida albicans cell wall proteins. M icrobiol Mol Biol Rev 2008 ; 72: 495-544
9. Schild L, Heyken A, de Groot PW, et al . Proteolytic cleavage of covalently linked cell wall proteins by Candida albicans Sap9 and Sap10 . Eukaryot Cell 2011 ; 10: 98-109
10. Nailis H, Kucharikova S, Ricicova M, et al . Real-time PCR expression profi ling of genes encoding potential virulence factors in Candida albicans biofilms: Identification of modeldependent and -independent gene expression . BMC Microbiol 2010; 10: 114
11. Song JW, Shin JH, Kee SJ, e t al . Expression of CgCDR1, CgCDR2, and CgERG11 in Candida glabrata biofilms formed by bloodstream isolates Med Mycol 2009 ; 47: 545-548
12. Chandra J, Mukherjee PK, Ghannoum MA . I n vitro growth and analysis of Candida biofilms . Nat Protoc 2008 ; 3: 1909-1924
13. Mores AU, Souza RD, Cavalca L, e t al . Enhancement of secretory aspartyl protease production in biofilms of Candida albicans exposed to subinhibitory concentrations of fl uconazole. Mycoses 2011; 54: 195- 201
14. Borg-von Zepelin M, Beggah S, Boggian K, e t al . The expression of the secreted aspartyl proteinases Sap4 to Sap6 from Candida albicans in murine macrophages . Mol Microbiol 1998 ; 28: 543-554
15. Albrecht A, Felk A, Pichova I, et al . Glycosylphosphatidylinositolanchored proteases of Candida albicans target proteins necessary for both cellular processes and host-pathogen interactions . J Biol Chem 2006 ; 281: 688-694
16. Schild L, Heyken A, de Groot PW, e t al . C ovalently linked cell wall proteins of Candida albicans nd heir role in fitness and virulence. Eukaryot Cell 2011 ; 10: 98-109