Metabolism of the plasticizer and phthalate substitute diisononyl- cyclohexane-1,2-dicarboxylate (DINCH®) in humans after single oral doses

Archives of Toxicology

Volumn 87, Issue 5, 2013, Pages 799-806

  Koch, Holger M ^a   Schütze, André ^a   Pälmke, Claudia ^a   Angerer, Jürgen ^a   Brüning, Thomas ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

DINCH; Excretion fractions; Human biomonitoring; Human metabolism; Phthalate substitute; Urinary metabolites

Indexed keywords

BIOLOGICAL MARKER; CARBOXYLIC ACID DERIVATIVE; CYCLOHEXANE 1,2 DICARBOXYLIC ACID; DICARBOXYLIC ACID DERIVATIVE; DIISONONYL CYCLOHEXANE 1,2 DICARBOXYLIC ACID; DIISONONYLPHTHALIC ACID; HEXAMOLL DINCH; MONOISONONYLCYCLOHEXANE 1,2 DICARBOXYLATE; PHTHALIC ACID DERIVATIVE; PLASTICIZER; UNCLASSIFIED DRUG; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE; DICARBOXYLIC ACID; DIISONONYL 1,2 CYCLOHEXANEDICARBOXYLIC ACID; DIISONONYL 1,2-CYCLOHEXANEDICARBOXYLIC ACID;

ADULT; ARTICLE; BODY WEIGHT; CHEMICAL ANALYSIS; CONTROLLED STUDY; CYCLOADDITION; DRUG ELIMINATION; DRUG EXCRETION; DRUG EXPOSURE; DRUG HALF LIFE; DRUG METABOLISM; DRUG URINE LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; MALE; MASS SPECTROMETRY; METABOLITE; NORMAL HUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; TANDEM MASS SPECTROMETRY; URINALYSIS; URINARY EXCRETION; URINE; YOUNG ADULT; HALF LIFE TIME; ORAL DRUG ADMINISTRATION; OXIDATION REDUCTION REACTION;

ADMINISTRATION, ORAL; ADULT; BIOLOGICAL MARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOHEXANECARBOXYLIC ACIDS; DICARBOXYLIC ACIDS; HALF-LIFE; HUMANS; MALE; OXIDATION-REDUCTION; PLASTICIZERS; TANDEM MASS SPECTROMETRY;

EID: 84885847251     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0990-4     Document Type: Article

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