Synthesis and antimycobacterial activity of isoniazid derivatives from renewable fatty acids

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 22, 2013, Pages 6910-6914

  Rodrigues, Marieli O ^a   Cantos, Jéssica B ^a   D'Oca, Caroline R Montes ^b   Soares, Karina L ^a   Coelho, Tatiane S ^a   Piovesan, Luciana A ^a   Russowsky, Dennis ^b   Da Silva, Pedro A ^a   D'Oca, Marcelo G Montes ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Antimycobacterial activity; Fatty acids; INH derivatives; Mycobacterium tuberculosis

Indexed keywords

6,9 N' OCTADECA 6,9 DIENOYLISONICOTINOHYDRAZIDE; 9,12,15 N' OCTADECA 9,12,15 TRIENOYLISONICOTINOHYDRAZIDE; ANTIMYCOBACTERIAL AGENT; FATTY ACID; ISONIAZID; ISONIAZID DERIVATIVE; N' (12 HYDROXYOCTADEC 9 ENOYL)ISONICOTINOHYDRAZIDE; N' HEXADECAISONICOTINOHYDRAZIDE; N' OCTADECA 9 ENOYLISONICOTINOHYDRAZIDE; N' OCTADECAISONICOTINOHYDRAZIDE; RIFAMPICIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; LIPOPHILICITY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHYSICAL CHEMISTRY; STRUCTURE ACTIVITY RELATION;

MYCOBACTERIUM TUBERCULOSIS;

ANTIMYCOBACTERIAL ACTIVITY; FATTY ACIDS; INH-DERIVATIVES; MYCOBACTERIUM TUBERCULOSIS;

ANTITUBERCULAR AGENTS; DRUG RESISTANCE, BACTERIAL; FATTY ACIDS; ISONIAZID; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; RIFAMPIN;

EID: 84885841218     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.09.034     Document Type: Article

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